Zmiana języka

Projects search

Development of EPR oximetry methodology for evaluation of endothelial action of drugs

2012/05/D/NZ7/02518

Keywords

Descriptors

  • NZ7_14: Farmacja, farmakoterapia, farmakologia

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Patrycja Kaczara

Number of co-investigators in the project: 1

Call

SONATA 3 – announced on 2012-03-15

Amount awarded
391 482 PLN
Project start date
2013-02-11
Project end date
2016-06-10
Project duration
40 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (4)

  1. Comparative endothelial profiling of doxorubicin and daunorubicin in cultured endothelial cells.

    Authors:
    Wojcik T, Buczek E, Majzner K, Kolodziejczyk A, Miszczyk J, Kaczara P, Kwiatek W, Baranska M, Szymonski M, Chlopicki S.
    Academic press:
    Toxicology in Vitro (year: 2015, volume: 29, pages: 512-521), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tiv.2014.12.009 – link to the publication

  2. Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: A role for mitoBK Ca channels

    Authors:
    Kaczara P, Motterlini R, Rosen GM, Augustynek B, Bednarczyk P, Szewczyk A, Foresti R, Chłopicki S
    Academic press:
    Biochimica et Biophysica Acta - Bioenergetics (year: 2015, volume: 1847, pages: 1297-1309), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbabio.2015.07.004 – link to the publication

  3. CORM‐401 induces calcium signalling, NO increase and activation of pentose phosphate pathway in endothelial cells

    Authors:
    Kaczara P, Proniewski B, Lovejoy C, Kus K, Motterlini R, Abramov AY, Chlopicki S
    Academic press:
    The FEBS Journal (year: 2018, volume: 285, pages: 1346-1358), Publisher: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
    Status:
    Published
    DOI:
    10.1111/febs.14411 – link to the publication

  4. Carbon monoxide shifts energetic metabolism from glycolysis to oxidative phosphorylation in endothelial cells

    Authors:
    Kaczara P, Motterlini R, Kus K, Zakrzewska A, Abramov AY, Chlopicki S
    Academic press:
    FEBS Letters (year: 2016, volume: 590, pages: 3469-3480), Publisher: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
    Status:
    Published
    DOI:
    10.1002/1873-3468.12434 – link to the publication

Articles in post-conference publications (6)

  1. Carbon monoxide regulates endothelial cells bioenergetics

    Authors:
    Kaczara P, Motterlini R, Zakrzewska A, Abramov AY, Chłopicki S
    Conference:
    19th European Bioenergetics Conference (EBEC) (year: 2016, pages: 59), Publisher: EBEC
    Date:
    conference 2 - 7 lipca 2016
    Status:
    Published

  2. EPR oximetry in estimating physiological state of aorta – ex vivo and in vitro study

    Authors:
    Kaczara P, Panz T, Chłopicki S
    Conference:
    IX International Workshop on EPR (ESR) In Biology and Medicine (year: 2013, pages: 120), Publisher: IX International Workshop on EPR (ESR) In Biology and Medicine
    Date:
    conference 7-10 października 2013
    Status:
    Published

  3. Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: a role for mitoBKCa channels

    Authors:
    Kaczara P, Motterlini R, Rosen GM, Augustynek B, Bednarczyk P, Szewczyk A, Foresti R, Chłopicki S
    Conference:
    VI Seminarium JCET, 23rd Kraków Conference on Endothelium (year: 2015, pages: 31), Publisher: JCET
    Date:
    conference 11-14 czerwca 2015
    Status:
    Published

  4. Effects of carbon monoxide released by CORM-401 on oxidative phosphorylation and glycolysis in endothelial cells

    Authors:
    Kaczara P, Foresti R, Motterlini R, Chłopicki S
    Conference:
    5th World Congress on Targeting Mitochondria (year: 2014, pages: 125), Publisher: World Mitochondria Society
    Date:
    conference 29 - 31 października 2014
    Status:
    Published

  5. Carbon monoxide regulates endothelial cells bioenergetics

    Authors:
    Kaczara P, Motterlini R, Zakrzewska A, Abramov AY, Chłopicki S
    Conference:
    VII Seminarium JCET, 24rd Kraków Conference on Endothelium (year: 2016, pages: 19), Publisher: JCET
    Date:
    conference 19-21 czerwcz 2016
    Status:
    Published

  6. Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: a role for mitoBKCa channels

    Authors:
    Kaczara P, Motterlini R, Rosen GM, Augustynek B, Bednarczyk P, Szewczyk A, Foresti R, Chłopicki S
    Conference:
    Metabolism in Cancer and Stromal Cells (year: 2015, pages: 86), Publisher: VIB Conference Series
    Date:
    conference 8 - 10 września 2015
    Status:
    Published

« New search

Graphic design and implementation: Jakub Piotrowski