Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Label-free imaging of subcelluar structures of endotelium using Confocal Raman Spectroscopy supported by FT-IR Spectroscopy, AFM and Fluorescence Microscopy

2013/09/N/ST4/00943

Keywords:

confocal Raman microspectroscopy 3D imaging fluorescence AFM lipid droplets endothelium

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_13: Solid-state chemistry, surface physicochemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Majzner 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 149 500 PLN

Project start date (Y-m-d): 2014-04-03

Project end date (Y-m-d): 2017-04-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Detektor CCD (35 000 PLN)
  2. Specjalistyczne oprogramowanie komputerowe (5 850 PLN)
  3. Komputer z 2 monitorami (5 078 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Raman microscopy as a novel tool to detect endothelial dysfunction
    Authors:
    M. Baranska, A. Kaczor, K. Malek, A. Jaworska, K. Majzner, E. Staniszewska-Slezak, M.Z. Pacia, G. Zajac, J. Dybas, E. Wiercigroch
    Academic press:
    Pharmacological Reports (rok: 2015, tom: 67, strony: 736-743), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharep.2015.03.015 - link to the publication
  2. Lipid droplets formation in human endothelial cells in response to polyunsaturated fatty acids and 1-methyl-nicotinamide (MNA); confocal Raman imaging and fluorescence microscopy studies
    Authors:
    K. Majzner, S. Chlopicki, M. Baranska
    Academic press:
    Journal of Biophotonics (rok: 2016, tom: 141, strony: 396-405), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/jbio.201500134 - link to the publication
  3. Uptake of fatty acids by a single endothelial cell investigated by Raman spectroscopy supported by AFM
    Authors:
    Katarzyna Majzner, Szymon Tott, Ludovic Roussille, Volker Deckert, Stefan Chlopicki, Malgorzata Baranska
    Academic press:
    Analyst (rok: 2018, tom: 4, strony: 970-980), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C7AN01043E - link to the publication

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