Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The role of urokinase-type plasminogen activator receptor in the process of endothelial microparticle formation and internalization in hyperglycemic conditions.

2014/15/N/NZ5/01606

Keywords:

canonical signaling Wnt pathways angiogenesis hyperglycemia endothelium uPAR

Descriptors:

  • NZ3_2: Cell physiology
  • NZ5_3: Pathogenesis of human diseases
  • NZ3_7: Signal transduction

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Martyna Durak-Kozica 

Number of co-investigators in the project: 2

Call: PRELUDIUM 8 - announced on 2014-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2015-09-22

Project end date (Y-m-d): 2018-09-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Role of the Wnt signalling pathway in the development of endothelial disorders in response to hyperglycaemia
    Authors:
    Martyna Durak-Kozica, Elżbieta Paszek, Ewa Stępień,
    Academic press:
    Expert Reviews in Molecular Medicine (rok: 2019, tom: 21, strony: 45303), Wydawca: Cambridge University Press
    Status:
    Published
    DOI:
    10.1017/erm.2019.8 - link to the publication
  2. 3D visualization of extracellular vesicles uptake by endothelial cells
    Authors:
    Martyna Durak-Kozica, Zbigniew Baster, Karol Kubat, Ewa Stępień
    Academic press:
    Cellular & Molecular Biology Letters (rok: 2018, tom: 23, strony: 45300), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s11658-018-0123-z - link to the publication
  3. Targeting uPAR in diabetic vascular pathologies
    Authors:
    Martyna Durak-Kozica, Francisco J. Enguita , Ewa Stępień
    Academic press:
    Postępy Higieny i Medycyny Doświadczalnej (rok: 2019, tom: 73, strony: 803-808), Wydawca: International Index Copernicus
    Status:
    Published
    DOI:
    10.5604/01.3001.0013.6909 - link to the publication
  1. Role of uPAR and hyperglycaemia in formation and internalization of endothelial-derived extracellular vesicles.
    Authors:
    Martyna Durak-Kozica, Magdalena Surman, Zbigniew Baster, Anna Drożdż, Małgorzata Przybyło, Ewa Stępień
    Conference:
    4th International Conference of Cell Biology (rok: 2018, ), Wydawca: 4th International Conference of Cell Biology
    Data:
    konferencja 11-12.05.2018
    Status:
    Published
  2. Charakterystyka i właściwości fibrynolityczne mikropęcherzyków pochodzących z śródbłonka otrzymywanych w warunkach hiperglikemii.
    Authors:
    Martyna Durak-Kozica, Andrzej Wróbel, Mark Platt, Rush Maugi, Magdalena Surman, Małgorzata Przybyło, Zbigniew Baster, Zenon Rajfur, Ewa Stępień
    Conference:
    XXXIV Sympozjum Sekcji Kardiologii Eksperymentalnej Polskiego Towarzystwa Kardiologicznego (rok: 2019, ), Wydawca: Folia Medica Cracoviensia
    Data:
    konferencja 28-30.11.2019
    Status:
    Published