Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Study of the influence of the drug physicochemical properties on its endothelial distribution and binding ability to plasma proteins.

2014/13/N/NZ7/00249

Keywords:

physicochemical properties drug distribution plasma protein binding endothelium

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Anna Gonciarz-Dytman 

Number of co-investigators in the project: 3

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 99 990 PLN

Project start date (Y-m-d): 2015-03-20

Project end date (Y-m-d): 2017-12-19

Project duration:: 33 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Mieszadło magnetyczne (1 500 PLN)
  2. Precyzyjny termometr z sondą.
  3. Lampa deuterowa.
  4. Pipeta laboratoryjna.
  5. Elektroda do pomiaru pH w środowisku niewodnym lub częściowo niewodnym (2 500 PLN)
  6. Komputer przenośny, Laptop (4 000 PLN)
  7. Filtry optyczne do detektora UV, DAD (5 280 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  1. Effects of structural modification of the daunosamine moiety of antracycline antibiotics on pKa values determined by capillary zone electrophoresis
    Authors:
    Matyjaszczyk, Karolina; Kolonko, Marta; Gonciarz-Dytman, Anna; Oszczapowicz, Irena; Lukawska, Malgorzata; Chlopicki, Stefan; Walczak, Maria
    Academic press:
    Journal of chromatography b (rok: 2017, tom: 1060, strony: 44-52), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jchromb.2017.04.038 - link to the publication