The role of LSD1 in the epigenetic regulation of transcription activity of NF-kappaB-dependent pro-inflammatory genes in endothelial cells.
2016/23/N/NZ3/02435
Keywords
Descriptors
- NZ3_1: Biologia komórki
- NZ1_1: Biologia molekularna
- NZ1_2: Biochemia
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska
Voivodeship: łódzkie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 12 – announced on 2016-09-15
- Amount awarded
- 99 600 PLN
- Project start date
- 2017-10-04
- Project end date
- 2020-10-03
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
The Role of Lysine-Specific Demethylase 1 (LSD1) in Shaping the Endothelial Inflammatory Response
- Authors:
- Martyna Wojtala, Dorota Rybaczek, Ewelina Wielgus, Marta Sobalska-Kwapi , Dominik Strapagiel , Aneta Balcerczyk
- Academic press:
- Cellular Physiology & Biochemistry (year: 2021, volume: 55, pages: 569-589), Publisher: Cell Physiol Biochem Press GmbH&Co. KG, Duesseldorf
- Status:
- Published
- DOI:
- 10.33594/000000436 – link to the publication
-
Silencing Lysine-Specific Histone Demethylase 1 (LSD1) Causes Increased HP1-Positive Chromatin, Stimulation of DNA Repair Processes, and Dysregulation of Proliferation by Chk1 Phosphorylation in Human Endothelial Cell
- Authors:
- Wojtala M, Dąbek A, Rybaczek D, Śliwińska A, Świderska E, Słapek K, El-Osta A, Balcerczyk A
- Academic press:
- Cells (year: 2019, volume: 8(10), pages: 1212), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/cells8101212 – link to the publication
Articles in post-conference publications (1)
-
LSD1 activity promotes LPS-induced inflammation of microvascular endothelial cells
- Authors:
- Martyna Wojtala, Dorota Rybaczek, Marta Sobalska-Kwapis, Aneta Balcerczyk
- Conference:
- The 9th Prof. Krzysztof W. Szewczyk Intercollegiate Biotechnology Symposium SYMBIOZA (year: 2021, pages: 113), Publisher: Warszawskie Towarzystwo Biotechnologiczne ,,Symbioza''
- Date:
- conference 21-23 maja
- Status:
- Published