Projects funded by the NCN
The role of LSD1 in the epigenetic regulation of transcription activity of NF-kappaB-dependent pro-inflammatory genes in endothelial cells.
2016/23/N/NZ3/02435
Keywords:
Lysine-specyfic demethylase 1 NF-kappaB inflammatory response endothelium
Descriptors:
- NZ3_1: Cell biology
- NZ1_1: Molecular biology
- NZ1_2: Biochemistry
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska
woj. łódzkie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 12 - announced on 2016-09-15
Amount awarded: 99 600 PLN
Project start date (Y-m-d): 2017-10-04
Project end date (Y-m-d): 2020-10-03
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- Articles in post-conference publications (1)
- The Role of Lysine-Specific Demethylase 1 (LSD1) in Shaping the Endothelial Inflammatory ResponseAuthors:Martyna Wojtala, Dorota Rybaczek, Ewelina Wielgus, Marta Sobalska-Kwapi , Dominik Strapagiel , Aneta BalcerczykAcademic press:Cellular Physiology & Biochemistry (rok: 2021, tom: 55, strony: 569-589), Wydawca: Cell Physiol Biochem Press GmbH&Co. KG, DuesseldorfStatus:PublishedDOI:10.33594/000000436 - link to the publication
- Silencing Lysine-Specific Histone Demethylase 1 (LSD1) Causes Increased HP1-Positive Chromatin, Stimulation of DNA Repair Processes, and Dysregulation of Proliferation by Chk1 Phosphorylation in Human Endothelial CellAuthors:Wojtala M, Dąbek A, Rybaczek D, Śliwińska A, Świderska E, Słapek K, El-Osta A, Balcerczyk AAcademic press:Cells (rok: 2019, tom: 8(10), strony: 1212), Wydawca: MDPIStatus:PublishedDOI:10.3390/cells8101212 - link to the publication
- LSD1 activity promotes LPS-induced inflammation of microvascular endothelial cellsAuthors:Martyna Wojtala, Dorota Rybaczek, Marta Sobalska-Kwapis, Aneta BalcerczykConference:The 9th Prof. Krzysztof W. Szewczyk Intercollegiate Biotechnology Symposium SYMBIOZA (rok: 2021, ), Wydawca: Warszawskie Towarzystwo Biotechnologiczne ,,Symbioza''Data:konferencja 21-23 majaStatus:Published