Search results

1. Search for early molecular mechanisms and markers of preclinical stage of sporadic form of Alzheimer's disease (SAD) in …

Principal investigator: dr Anna Mietelska-Porowska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: SONATA 8, Panel: NZ4

2. Western diet as a potent risk factor of Alzheimer's disease progression: influence of a long-term Western diet feeding o…

Principal investigator: Angelika Elżbieta Więckowska-Gacek

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 15, Panel: NZ7

3. Autophagy stimulation by genistein to cure Alzheimer disease: mechanisms and effects investigated using genetic (cellula…

Principal investigator: prof. Grzegorz Władysław Węgrzyn

Uniwersytet Gdański

Call: OPUS 27, Panel: NZ2

4. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif…

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 28, Panel: NZ7

5. Biased inverse agonists of 5-HT6 receptor and dual 5-HT6/MAO-B inhibitors - in search for new therapeutic approaches for…

Principal investigator: prof. Paweł Maria Zajdel

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 11, Panel: NZ7

6. Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu…

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 24, Panel: NZ7

7. The first antibody-drug conjugates for Alzheimer's disease therapy

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska

Call: SONATA BIS 14, Panel: NZ5

8. ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

Principal investigator: dr hab. Anna Ludwika Haduch

Instytut Farmakologii PAN

Call: M-ERA.NET 3 Call 2023, Panel: NZ5

9. Potential neuroprotective properties of modulators of sphingosine-1-phosphate (S1P) receptors (fingolimod and siponimod)…

Principal investigator: Iga Wieczorek

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 20, Panel: NZ5

10. Looking for the same pathological factors in ischemic brain and Alzheimer's disease;Genes

Principal investigator: prof. Ryszard Pluta

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 5, Panel: NZ7

11. Defining (sex and age) cell-specific epigenetic mechanisms underlying EnvironmentalEnrichment/Exercise as non-pharmacolo…

Principal investigator: dr hab. Bartosz Zbigniew Wilczyński

Uniwersytet Warszawski

Call: JPND Call 2022, Panel: NZ2

12. Deciphering the Chemoproteomics and Chemotranscriptomics of Anti-Alzheimer Drugs for Novel Druggable Target Identificati…

Principal investigator: prof. Krzysztof Sobczak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: JPND Call 2023, Panel: NZ5

13. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

Principal investigator: Karolina Barbara Przepiórska-Drońska

Instytut Farmakologii PAN

Call: PRELUDIUM 21, Panel: NZ7

14. Effects of activation of cholinergic, noradrenergic, and serotonergic systems on respiratory impairment in Alzheimer's d…

Principal investigator: prof. Katarzyna Kaczyńska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 23, Panel: NZ7

15. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

Principal investigator: prof. Kinga Aleksandra Sałat

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 22 (LAP), Panel: NZ7

16. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic…

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 20, Panel: NZ7

17. MicroRNAs in blood as biomarkers for Alzheimer's disease: molecular signature for personalized therapy

Principal investigator: prof. Urszula Wojda

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 15, Panel: NZ7

18. Functional, epigenetic and genetic aspects of base excision repair pathway in Alzheimer's disease

Principal investigator: dr hab. Tomasz Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 3, Panel: NZ7

19. Study of the regenerative potential of Stem Cells from Human Exfoliated Deciduous teeth (SHED) in Alzheimer's disease

Principal investigator: dr Leila Elyasi

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: POLONEZ BIS 3, Panel: NZ3

20. Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D…

Principal investigator: Kinga Maria Czarnota-Łydka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 21, Panel: NZ7

21. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer…

Principal investigator: Anna Marta Pasieka

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

22. Towards innovative strategy for treatment of Alzheimer's Disease via dual inhibition of receptor 5-HT6 and kinase CDK5.

Principal investigator: Sylwia Sudoł-Tałaj

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

23. Novel role of peroxisome proliferator-activated receptor α in the regulationof amyloid β peptide metabolism and mitochon…

Principal investigator: dr Sylwia Żulińska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 18, Panel: NZ4

24. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm…

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA BIS 9, Panel: NZ7

25. Role of Pon1 in Alzheimer Disease.

Principal investigator: prof. Hieronim Jakubowski

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Bioinżynierii

Call: OPUS 15, Panel: NZ4

26. Anilide derivatives of long-chain cyclic amines as multifunctional serotonin receptors ligands and phosphodiesterase 7 i…

Principal investigator: dr Agnieszka Wioleta Jankowska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 13, Panel: NZ7

27. Synthesis and biological evaluation of novel, drug-like multifunctional ligands, as potential anti-Alzheimer's agents ta…

Principal investigator: Dawid Marcin Panek

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 11, Panel: NZ7

28. Neuroprotective role of the GPR39 receptor in the central nervous system. Its relationship to Alzheimer Disease.

Principal investigator: dr hab. Katarzyna Młyniec

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 10, Panel: NZ7

29. Determination of physicochemical and biochemical propertiess of natural pyridine and piperidine alkaloids and their simp…

Principal investigator: dr Damian Andrzej Szczesny

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Call: PRELUDIUM 4, Panel: NZ7

30. A new concept of inhibiting the progression of Alzheimer's disease based on the modification of the blood-brain barrier …

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Call: OPUS 28, Panel: NZ4

31. Effect of phosphorylation of Aβ peptides on the redox activity oftheir copper complexes and aggregation in the context o…

Principal investigator: dr Nina Ewa Wezynfeld

Politechnika Warszawska, Wydział Chemiczny

Call: SONATA 19, Panel: ST4

32. Bleomycin hydrolase, homocysteine metabolism, epigenetic regulation of mTOR signalling, autophagy, and Alzheimer's disea…

Principal investigator: dr hab. Joanna Perła-Kaján

Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

Call: OPUS 22, Panel: NZ4

33. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical…

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Call: OPUS 22, Panel: NZ4

34. Spectroelectrochemistry of Alzheimer's disease - a study of a new potential therapeutic molecule

Principal investigator: dr Magdalena Zofia Wiloch-Szyborska

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: SONATINA 5, Panel: ST4

35. Alzheimer's disease as a co-morbidity of chronic periodontitis with Porphyromonas gingivalis as a causative link between…

Principal investigator: prof. Jan Stanisław Potempa

Uniwersytet Jagielloński

Call: JPND2019, Panel: NZ1

36. Executive attention, genetic risk of Alzheimer's disease and cingulate cortex: an EEG and fMRI study

Principal investigator: Patrycja Joanna Dzianok

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 16, Panel: HS6

37. The role of BET family proteins in microglia-dependent neurodegeneration; relevance to Alzheimer's disease

Principal investigator: dr hab. Grzegorz Arkadiusz Czapski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 16, Panel: NZ4

38. Inhibitors of ER stress dependant PERK kinase as a novel approach for Alzheimer's therapy

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski

Call: HARMONIA 5, Panel: NZ1

39. Conjugates of prion protein with dendrimers as inhibitors of Abeta peptide amyloidogenesis and cytotoxicity of potential…

Principal investigator: dr hab. Krzysztof Nieznański

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: HARMONIA 5, Panel: NZ4

40. The influence of dimethyl fumarate on the spatial memory, neurogenesis, neurodegeneration and cerebral imflammation in t…

Principal investigator: dr Irena Maria Majkutewicz

Uniwersytet Gdański, Wydział Biologii

Call: SONATA 5, Panel: NZ4

41. FUNCTIONAL STUDIES OF RARE GENETIC VARIANTS OF GENES CAUSSALLY CONNECTED WITH ALZHEIMER'S DISEASE IN THE POLISH POPULATI…

Principal investigator: dr Michalina Maria Wężyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 5, Panel: NZ3

42. The role of CDK5 in inflammatory reaction in experimental model of Alzheimer's disease

Principal investigator: dr hab. Grzegorz Arkadiusz Czapski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 2, Panel: NZ3

43. Transgenic mice with elevated basal level of calcium ions in neurons as a model of aged-induced neurodegeneration of spo…

Principal investigator: prof. Jacek Marceli Kuźnicki

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: MAESTRO 1, Panel: NZ3

44. New perspective in Alzheimer's disease therapy - multifunctional histamine H3 receptor ligands?

Principal investigator: dr hab. Dorota Łażewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 12, Panel: NZ7

45. Cortical reinstatement in health and Alzheimer's' disease: a direct approach to testing the hippocampal memory indexing …

Principal investigator: dr Rafał Czajkowski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: CEUS-UNISONO, Panel: NZ4

46. (Micro)RNA and informatics approaches for diagnosis, prognosis and treatment of Alzheimer's disease and Dementia

Principal investigator: dr hab. Agnieszka Fiszer

Instytut Chemii Bioorganicznej PAN

Call: JPND Call 2023, Panel: NZ3

47. Presymptomatic synaptic disorders in Alzheimer's disease

Principal investigator: dr Michalina Maria Wężyk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: JPco-fuND2 Call 2021, Panel: NZ5

48. An attempt to elucidate the role of clusterin and lipid rafts in Alzheimer's disease etiology.

Principal investigator: prof. Arkadiusz Bernard Orzechowski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 2, Panel: NZ7

49. The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe…

Principal investigator: prof. Joanna Benigna Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 5, Panel: NZ3

50. The role of bioactive sphingolipids: ceramide, ceramide-1-phosphate and sphingosine-1-phosphate in regulation of mitocho…

Principal investigator: dr hab. Robert Piotr Strosznajder

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 8, Panel: NZ3

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