Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Western diet as a potent risk factor of Alzheimer's disease progression: influence of a long-term Western diet feeding on activation of resident microglia and monocyte-derived macrophages in early stage of Alzheimer's disease development

2018/29/N/NZ7/01724

Keywords:

dieta typu zachodniego choroba Alzheimera stan zapalny mózgu ogólnoustrojowy stan zapalny

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ4_7: Neurophysiology
  • NZ4_11: Metabolism

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Angelika Więckowska-Gacek 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 140 000 PLN

Project start date (Y-m-d): 2019-01-21

Project end date (Y-m-d): 2023-01-20

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Western Diet Induces Impairment of Liver-Brain Axis Accelerating Neuroinflammation and Amyloid Pathology in Alzheimer's Disease
    Authors:
    Angelika Wiȩckowska-Gacek, Anna Mietelska-Porowska, Dominik Chutorański, Małgorzata Wydrych, Jan Długosz, Urszula Wojda
    Academic press:
    Frontiers in Aging Neuroscience (rok: 2021, tom: brak, strony: brak), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fnagi.2021.654509. - link to the publication
  2. Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration
    Authors:
    Angelika Więckowska-Gacek, Anna Mietelska-Porowska, Małgorzata Wydrych, Urszula Wojda
    Academic press:
    Ageing Research Reviews (rok: 2021, tom: 70, strony: 45314), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.arr.2021.101397 - link to the publication
  1. Western diet- from metabolic duisturbances to acceleration of glia activation and development of Alzheimer's disease
    Authors:
    Więckowska A, Mietelska-Porowska A., Wydrych M., Długosz J., Chutorański D., Wojda U.
    Conference:
    14th International Congress of the Polish Neuroscience Society, Katowice, Poland (rok: 2019, ), Wydawca: Acta Neurobiologiae Experimentalis, volume 79, Abstr P1.12
    Data:
    konferencja 43706
    Status:
    Published
  2. WESTERN DIET AS A TRIGGER OF ALZHEIMER'S DISEASE: FROM METABOLIC SYNDROME TO NEURODEGENERATION
    Authors:
    Angelika Więckowska-Gacek, Angelika Więckowska-Gacek, Andrew Want, Dominik Chutorański, Urszula Wojda
    Conference:
    12th Neuronus 2022 Neuroscience Forum (rok: 2022, ), Wydawca: Acta Neurobiologiae Experimentalis, volume 82, Supplement
    Data:
    konferencja 15-17 października 2022
    Status:
    Published
  3. WESTERN DIET – FROM MICROGLIA DYSFUNCTION TO THE ACCELERATION OF ALZHEIMER'S DISEASE PATHOLOGY
    Authors:
    Angelika Więckowska-Gacek, Anna Mietelska‑Porowska, Justyna Domańska, Urszula Wojda
    Conference:
    12th Neuronus 2022 Neuroscience Forum (rok: 2022, ), Wydawca: Acta Neurobiologiae Experimentalis, volume 82, Supplement
    Data:
    konferencja 15-17 października 2022
    Status:
    Published

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