Projects funded by the NCN
An attempt to elucidate the role of clusterin and lipid rafts in Alzheimer's disease etiology.
2011/03/B/NZ7/02328
Keywords:
clusterin cholesterol secretases amyloid precursor protein beta amyloid PC12 cells kinases transcription factors
Descriptors:
- NZ7_12:
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN
woj. mazowieckie
Principal investigator (from the host institution):
prof. Arkadiusz Bernard Orzechowski
Number of co-investigators in the project: 5
Call: OPUS 2 - announced on 2011-09-15
Amount awarded: 690 722 PLN
Project start date (Y-m-d): 2012-09-03
Project end date (Y-m-d): 2016-03-02
Project duration:: 42 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Czytnik wielopłytek model INFINITE M1000 firmy TECAN (338 942 PLN)
- Mikrowirówka (minispin) firmy ROTH.
Information in the final report
- Publication in academic press/journals (1)
- Nucleofection of Rat Pheochromocytoma PC-12 Cells with Human Mutated Beta-Amyloid Precursor Protein Gene (APP-sw) Leads to Reduced Viability, Autophagy-Like Process, and Increased Expression and Secretion of Beta AmyloidAuthors:Beata Pająk, Elżbieta Kania, Arkadiusz OrzechowskiAcademic press:Biomed Research International (Journal of Biomedicine and Biotechnology) (rok: 2014, tom: 2015, strony: 10), Wydawca: Hindawi Publishing CorporationStatus:PublishedDOI:10.1155/2015/746092 - link to the publication