Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic Alzheimer's Disease
2020/39/B/NZ7/00974
Keywords
Descriptors
- NZ7_014: Farmacja, farmakoterapia, farmakologia
- NZ3_005: Neurobiologia molekularna
- NZ7_012: Prewencja chorób człowieka
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Instytut Farmakologii PAN
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 5
Call
OPUS 20 – announced on 2020-09-15
- Amount awarded
- 1 451 800 PLN
- Project start date
- 2021-07-27
- Project end date
- 2025-07-26
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Project completed
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (1)
-
Posttreatment with PaPE-1 Protects from Aβ-Induced Neurodegeneration Through Inhibiting the Expression of Alzheimer's Disease-Related Genes and Apoptosis Process That Involves Enhanced DNA Methylation of Specific Genes
- Authors:
- Pietrzak-Wawrzyńska BA, Wnuk A, Przepiórska-Drońska K, Łach A, Kajta M
- Academic press:
- Mol Neurobiol (year: 2023, volume: praca dostępna, ale bez podania nr tomu, pages: praca dostępna, ale bez podania nr stron), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s12035-023-03819-5 – link to the publication