Projects funded by the NCN


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192 projects found matching your search criteria :

  1. The impact of S6K1 and S6K2 kinases on the efficiency of lysosomal degradation of cellular structures

    Call: PRELUDIUM 3 , Panel: NZ3

    Principal investigator: dr Aleksandra Hać

    Uniwersytet Gdański, Wydział Biologii

  2. The role of Parkin in exogenous Alpha-synuclein-induced cell death. Implications for pathogenesis of Parkinson's disease...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr hab. Agata Adamczyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  3. Assembly analysis of MAPKKK18 protein complexes: characterisation of MAPKKK18-dependent ABA signalling pathway

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Agnieszka Ludwików

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  4. Expression of pyruvate kinase in ovarian cancers.

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Christopher Kobierzycki

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

  5. Modification of glomerular filtration barrier permeability by the insulin, oxidative stress and protein kinase G type I ...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  6. Contribution of calcium-dependent protein kinases (CDPKs) to signalling pathways of abiotic and biotic stresses in potat...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Lidia Polkowska-Kowalczyk

    Instytut Biochemii i Biofizyki PAN

  7. Mechanisms underlaying the signaling function of PKC beta I and beta II in mitochondria after cerebral ischemia

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: prof. Barbara Zabłocka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  8. The role of the FAM69 protein family in the nervous system.Analysis of a novel family with potential protein kinase func...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr hab. Krzysztof Pawłowski

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Rolnictwa i Biologii

  9. The role of sirtuins and AMPK protein kinase in insulin resistance of podocytes

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr Dorota Rogacka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  10. Czy hiperaktywacja kinazy mTOR prowadzi do zaburzeń różnicowania komórek nerwowych?

    Call: FUGA 1 , Panel: NZ3

    Principal investigator: dr Bartosz Tarkowski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  11. An attempt to elucidate the role of clusterin and lipid rafts in Alzheimer's disease etiology.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Arkadiusz Orzechowski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  12. PIM kinases as rational therapeutic targets in lymphoid malignancies.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  13. The role of SnRK2 kinases in plant response to environmental stresses. The interplay between SnRK2 kinases, PP2C phospha...

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: prof. Grażyna Dobrowolska

    Instytut Biochemii i Biofizyki PAN

  14. Investigation of histidine phosphorylation in thymidylate synthase and searching for causative protein kinase

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: dr hab. Joanna Cieśla

    POLITECHNIKA WARSZAWSKA

  15. CacyBP/SIP as a novel phosphatase in signaling pathways related to cell proliferation and differentiation

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Anna Filipek

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  16. Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Artur Świerczek

    Uniwersytet Jagielloński, Collegium Medicum

  17. Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

    Call: SONATA 19 , Panel: NZ1

    Principal investigator: dr Anna Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  18. Deciphering the importance of the intracellular FGFR1 module for cell fate

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: dr hab. Małgorzata Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  19. Regulation of clathrin-dependent endocytosis by mTOR kinase in neuronal development

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: prof. Jacek Jaworski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  20. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński, Collegium Medicum

  21. Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Magdalena Wujak

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  22. Novel aspects of the mechanisms of vascular toxicity of tyrosine kinase inhibitors: studies on their proinflammatory act...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr Tomasz Prajsnar

    Uniwersytet Jagielloński, Wydział Biologii

  23. Fundamental laws of nature and their roles in metaphysics

    Call: SONATA 19 , Panel: HS1

    Principal investigator: dr Joanna Luc

    Uniwersytet Jagielloński, Wydział Filozoficzny

  24. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  25. Molecular mechanisms of DNA damage triggered by PIM kinases inhibition and its consequences for activation of innate imm...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  26. Investigating the mechanisms of CD20 downregulation triggered by tyrosine kinase inhibitors in Philadelphia chromosome-p...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Krzysztof Domka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  27. Regulacja procesu deoksyhypuzynacji przez kinazy białkowe

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Paweł Kochanowski

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  28. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  29. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marika Frańczak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  30. The potassium puzzle: unraveling the connection between the potassium channel and lipid kinases in kidney functioning

    Call: OPUS 25 , Panel: NZ1

    Principal investigator: dr hab. Piotr Koprowski

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  31. The effect of PKC epsilon modification on autophagy in cancer cells.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Maria Rybczyńska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  32. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  33. Effects of tyrosine kinase inhibitors on Syk pathway in eNOS-based platelet subpopulations and on endothelial barrier in...

    Call: POLONEZ BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Aneta Radziwon-Balicka

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  34. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

    Call: OPUS 24 (LAP) , Panel: NZ7

    Principal investigator: dr hab. Anna Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  35. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Sławomir Kasperowicz

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  36. Smart tissue engineering to change the paradigm of diabetes treatment

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  37. Unraveling mechanisms and physiological outcome of lipid-evoked regulation of proteostasis in the intestine.

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: dr hab. Grzegorz Sumara

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  38. The SnRK2 kinases as key proteins in seeds biology- unraveling new molecular mechanisms determining seed germination abi...

    Call: OPUS 23 , Panel: NZ3

    Principal investigator: dr Anna Kulik

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  39. Jasmonic acid biosynthesis enviromental regulation through mitogen-activated protein kinases in Arabidopsis thaliana.

    Call: SONATA 1 , Panel: NZ3

    Principal investigator: dr Łukasz Gałgański

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  40. Analysis of molecular background of clear cell renal cell carcinoma and role of MCPIP1 in tomorigenesis

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Jolanta Jura

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  41. Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Maciej Szydłowski

    Instytut Hematologii i Transfuzjologii

  42. Novel broad-spectrum central nervous system active substances: optimization of their multi-target profile

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kaczor

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  43. Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Ireneusz Majsterek

    Uniwersytet Medyczny w Łodzi

  44. New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Anna Florczak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  45. Cinemagoing in German-occupied Poland: Cinema programming and film preferences of multi-ethnic urban audiences during Wo...

    Call: OPUS 22 , Panel: HS2

    Principal investigator: dr hab. Andrzej Dębski

    Uniwersytet Wrocławski, Centrum Studiów Niemieckich i Europejskich im. Willy Brandta

  46. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: prof. Kinga Sałat

    Uniwersytet Jagielloński, Collegium Medicum

  47. Investigation of the MLK4 biology in breast cancer and search for new therapeutic strategies using innovative PROTAC com...

    Call: SONATA BIS 11 , Panel: NZ5

    Principal investigator: dr Anna Marusiak

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  48. RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Mikołaj Czajkowski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  49. Expression, regulation and function of super-enhancer non-coding RNAs in Diffuse Large B-Cell Lymphoma (DLBCL)

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Sonia Dębek

    Instytut Hematologii i Transfuzjologii

  50. Poetics of queer cinema

    Call: OPUS 2 , Panel: HS2

    Principal investigator: dr hab. Małgorzata Radkiewicz

    Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej