Projects funded by the NCN


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201 projects found matching your search criteria :

  1. Regulation of mTOR kinase signaling pathway by ESCRT-II complex in dendritogenesis.

    Call: PRELUDIUM 4 , Panel: NZ3

    Principal investigator: Marcelina Pieprzyk

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  2. The impact of S6K1 and S6K2 kinases on the efficiency of lysosomal degradation of cellular structures

    Call: PRELUDIUM 3 , Panel: NZ3

    Principal investigator: dr Aleksandra Agata Hać

    Uniwersytet Gdański, Wydział Biologii

  3. The role of Parkin in exogenous Alpha-synuclein-induced cell death. Implications for pathogenesis of Parkinson's disease...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr hab. Agata Adamczyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  4. Assembly analysis of MAPKKK18 protein complexes: characterisation of MAPKKK18-dependent ABA signalling pathway

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Agnieszka Ludwików

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  5. Expression of pyruvate kinase in ovarian cancers.

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Christopher Kamil Kobierzycki

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski

  6. Modification of glomerular filtration barrier permeability by the insulin, oxidative stress and protein kinase G type I ...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  7. Contribution of calcium-dependent protein kinases (CDPKs) to signalling pathways of abiotic and biotic stresses in potat...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr Lidia Polkowska-Kowalczyk

    Instytut Biochemii i Biofizyki PAN

  8. Mechanisms underlaying the signaling function of PKC beta I and beta II in mitochondria after cerebral ischemia

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: prof. Barbara Małgorzata Zabłocka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  9. The role of the FAM69 protein family in the nervous system.Analysis of a novel family with potential protein kinase func...

    Call: OPUS 3 , Panel: NZ3

    Principal investigator: dr hab. Krzysztof Piotr Pawłowski

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Rolnictwa i Biologii

  10. The role of sirtuins and AMPK protein kinase in insulin resistance of podocytes

    Call: OPUS 3 , Panel: NZ5

    Principal investigator: dr Dorota Rogacka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  11. Czy hiperaktywacja kinazy mTOR prowadzi do zaburzeń różnicowania komórek nerwowych?

    Call: FUGA 1 , Panel: NZ3

    Principal investigator: dr Bartosz Michał Tarkowski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  12. An attempt to elucidate the role of clusterin and lipid rafts in Alzheimer's disease etiology.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Arkadiusz Bernard Orzechowski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  13. PIM kinases as rational therapeutic targets in lymphoid malignancies.

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  14. The role of SnRK2 kinases in plant response to environmental stresses. The interplay between SnRK2 kinases, PP2C phospha...

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: prof. Grażyna Anna Dobrowolska

    Instytut Biochemii i Biofizyki PAN

  15. Phosphorylation-Dependent Regulation of IRS2 by DYRK1A: Implications for Diabetes Therapy

    Call: PRELUDIUM 24 , Panel: NZ1

    Principal investigator: Alicja Bis

    Uniwersytet Jagielloński

  16. Identification of the regulon and interactome of orphan histidine kinase in Streptomyces coelicolor A3(2)

    Call: PRELUDIUM 24 , Panel: NZ2

    Principal investigator: Mateusz Wenecki

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  17. Graphene Oxide-Immobilized Adenylate Kinase as a Molecular Mediator of Vascular Homeostasis

    Call: PRELUDIUM 24 , Panel: NZ1

    Principal investigator: Agata Wikarska

    Uniwersytet Mikołaja Kopernika

  18. Analysis of pharmacokinetic, pharmacodynamic and molecular determinants of intolerance and resistance to the Janus kinas...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Marta Katarzyna Karaźniewicz-Łada

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  19. Investigation of histidine phosphorylation in thymidylate synthase and searching for causative protein kinase

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: dr hab. Joanna Cieśla

    Politechnika Warszawska

  20. Mechanisms of Antidepressant Action of Psilocybin: The Role of 5-HT2B-5-HT1A Receptor Dimerization and GSK-3β Activation...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Agata Faron-Górecka

    Instytut Farmakologii PAN

  21. Regulatory role of the N-terminal fragment of diacylglycerol kinase-ε and its contribution to the pro-inflammatory respo...

    Call: PRELUDIUM 23 , Panel: NZ3

    Principal investigator: Gabriela Traczyk

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  22. Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o...

    Call: OPUS 27 , Panel: NZ5

    Principal investigator: dr Katarzyna Anna Malarz

    Politechnika Śląska

  23. CacyBP/SIP as a novel phosphatase in signaling pathways related to cell proliferation and differentiation

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Anna Filipek

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  24. Animal Adaptations: Film Adaptations of Literary Animal Characters, from the Silent Screen to Hollywood's Golden Age

    Call: OPUS 27 , Panel: HS2

    Principal investigator: dr hab. Justyna Ewa Włodarczyk

    Uniwersytet Warszawski

  25. Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Artur Świerczek

    Uniwersytet Jagielloński, Collegium Medicum

  26. Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

    Call: SONATA 19 , Panel: NZ1

    Principal investigator: dr Anna Marta Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  27. Deciphering the importance of the intracellular FGFR1 module for cell fate

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  28. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński, Collegium Medicum

  29. Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Magdalena Wujak

    Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  30. Regulation of clathrin-dependent endocytosis by mTOR kinase in neuronal development

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: prof. Jacek Ryszard Jaworski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  31. Novel aspects of the mechanisms of vascular toxicity of tyrosine kinase inhibitors: studies on their proinflammatory act...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr Tomasz Krzysztof Prajsnar

    Uniwersytet Jagielloński, Wydział Biologii

  32. Fundamental laws of nature and their roles in metaphysics

    Call: SONATA 19 , Panel: HS1

    Principal investigator: dr Joanna Luc

    Uniwersytet Jagielloński, Wydział Filozoficzny

  33. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem...

    Call: PRELUDIUM BIS 5 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Firczuk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  34. Molecular mechanisms of DNA damage triggered by PIM kinases inhibition and its consequences for activation of innate imm...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  35. Investigating the mechanisms of CD20 downregulation triggered by tyrosine kinase inhibitors in Philadelphia chromosome-p...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Krzysztof Domka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  36. Regulacja procesu deoksyhypuzynacji przez kinazy białkowe

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Paweł Kochanowski

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  37. Search for novel IKK-β inhibitors in the context of diseases with neuroinflammatory origin – structure-based drug design...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Emilia Aleksandra Sługocka

    Uniwersytet Jagielloński, Collegium Medicum

  38. INVADOPODIA IN AXL-DRIVEN CANCER INVASION AND DRUG RESISTANCE

    Call: OPUS 25 , Panel: NZ3

    Principal investigator: dr Daria Paulina Zdżalik-Bielecka

    Uniwersytet Warszawski, Wydział Biologii

  39. Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

    Call: PRELUDIUM 22 , Panel: NZ7

    Principal investigator: Marika Anna Frańczak

    Gdański Uniwersytet Medyczny, Wydział Lekarski

  40. The potassium puzzle: unraveling the connection between the potassium channel and lipid kinases in kidney functioning

    Call: OPUS 25 , Panel: NZ1

    Principal investigator: dr hab. Piotr Rajmund Koprowski

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  41. The effect of PKC epsilon modification on autophagy in cancer cells.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Maria Jolenta Rybczyńska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  42. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt...

    Call: OPUS 24 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  43. Effects of tyrosine kinase inhibitors on Syk pathway in eNOS-based platelet subpopulations and on endothelial barrier in...

    Call: POLONEZ BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Aneta Iwona Radziwon-Balicka

    Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

  44. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis...

    Call: OPUS 24 (LAP) , Panel: NZ7

    Principal investigator: dr hab. Anna Karolina Więckowska

    Uniwersytet Jagielloński, Collegium Medicum

  45. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: dr Sławomir Jan Kasperowicz

    Instytut Biochemii i Biofizyki PAN

  46. Smart tissue engineering to change the paradigm of diabetes treatment

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  47. Unraveling mechanisms and physiological outcome of lipid-evoked regulation of proteostasis in the intestine.

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: dr hab. Grzegorz Piotr Sumara

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  48. The SnRK2 kinases as key proteins in seeds biology- unraveling new molecular mechanisms determining seed germination abi...

    Call: OPUS 23 , Panel: NZ3

    Principal investigator: dr Anna Marta Kulik

    Instytut Biochemii i Biofizyki PAN

  49. Analysis of molecular background of clear cell renal cell carcinoma and role of MCPIP1 in tomorigenesis

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Jolanta Jura

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  50. Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Maciej Stefan Szydłowski

    Instytut Hematologii i Transfuzjologii