Search results

51. The study of synergistic inhibition of tumor cell proliferation by CK2 casein kinase inhibitors and inhibitors of thymid…

Principal investigator: prof. Maria Wanda Bretner

Politechnika Warszawska, Wydział Chemiczny

Call: OPUS 7, Panel: NZ7

52. Understanding the mechanism of action for small molecule kinase inhibitors in alleviating myotonic dystrophy type 1 (DM1…

Principal investigator: dr hab. Marzena Wojciechowska

Instytut Chemii Bioorganicznej PAN

Call: OPUS 7, Panel: NZ5

53. Binding interactions of activators in the bacterial adenylate kinases

Principal investigator: Agnieszka Ludwiczak

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: PRELUDIUM 7, Panel: ST4

54. Lyn tyrosine kinase as regulator of lipopolysaccharide-triggered TLR4 pro-inflammatory signaling

Principal investigator: dr Kinga Borzęcka-Solarz

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 7, Panel: NZ3

55. Involvement of SnRK2 kinases in regulation of redox status in plant response to environmental stress

Principal investigator: dr Katarzyna Patrycja Szymańska

Instytut Biochemii i Biofizyki PAN

Call: PRELUDIUM 6, Panel: NZ1

56. Inhibition of p21-Activated Kinase (PAK) as a new molecular target in the treatment of chronic myeloid leukemia (CML)

Principal investigator: dr hab. Sylwia Flis

Narodowy Instytut Leków

Call: OPUS 6, Panel: NZ7

57. Hydration effects in protein kinases

Principal investigator: dr Piotr Mikołaj Setny

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: SONATA 6, Panel: ST4

58. Inhibitors of ER stress dependant PERK kinase as a novel approach for Alzheimer's therapy

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski

Call: HARMONIA 5, Panel: NZ1

59. Mechanism regulating vitamin D analog cooperation with cytostatics and tyrosine kinase inhibitors in non-small cell lung…

Principal investigator: dr Ewa Agnieszka Maj

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 5, Panel: NZ4

60. Expression of pyruvate kinase in ovarian cancers.

Principal investigator: Christopher Kamil Kobierzycki

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski

Call: PRELUDIUM 3, Panel: NZ4

61. Modification of glomerular filtration barrier permeability by the insulin, oxidative stress and protein kinase G type I …

Principal investigator: dr hab. Agnieszka Piwkowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 3, Panel: NZ4

62. Contribution of calcium-dependent protein kinases (CDPKs) to signalling pathways of abiotic and biotic stresses in potat…

Principal investigator: dr Lidia Polkowska-Kowalczyk

Instytut Biochemii i Biofizyki PAN

Call: OPUS 3, Panel: NZ3

63. The role of the FAM69 protein family in the nervous system.Analysis of a novel family with potential protein kinase func…

Principal investigator: dr hab. Krzysztof Piotr Pawłowski

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Rolnictwa i Biologii

Call: OPUS 3, Panel: NZ3

64. PIM kinases as rational therapeutic targets in lymphoid malignancies.

Principal investigator: dr hab. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Call: OPUS 2, Panel: NZ4

65. Investigation of histidine phosphorylation in thymidylate synthase and searching for causative protein kinase

Principal investigator: dr hab. Joanna Cieśla

Politechnika Warszawska

Call: OPUS 2, Panel: NZ1

66. Study of casein kinase CK2 inhibition mechanisms

Principal investigator: prof. Maria Wanda Bretner

Politechnika Warszawska, Wydział Chemiczny

Call: OPUS 1, Panel: ST5

67. Analysis of immune responses of rats after vaccination with cDNA encoding Fasciola hepatica phosphoglycerate kinase and …

Principal investigator: dr Agnieszka Wesołowska

Instytut Parazytologii im. Witolda Stefańskiego PAN

Call: PRELUDIUM 1, Panel: NZ6

68. Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole…

Principal investigator: dr Artur Świerczek

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 19, Panel: NZ7

69. Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

Principal investigator: dr Anna Marta Kocyła

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: SONATA 19, Panel: NZ1

70. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect…

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 26, Panel: NZ7

71. Molecular mechanisms of DNA damage triggered by PIM kinases inhibition and its consequences for activation of innate imm…

Principal investigator: prof. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Call: OPUS 25, Panel: NZ5

72. The SnRK2 kinases as key proteins in seeds biology- unraveling new molecular mechanisms determining seed germination abi…

Principal investigator: dr Anna Marta Kulik

Instytut Biochemii i Biofizyki PAN

Call: OPUS 23, Panel: NZ3

73. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis …

Principal investigator: Kaja Urszula Karaś

Instytut Biologii Medycznej PAN

Call: PRELUDIUM 18, Panel: NZ7

74. Role of heteromultimerization of MRCK kinases in physiological and pathological processes.

Principal investigator: Brygida Karolina Baran

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: PRELUDIUM 18, Panel: NZ3

75. The use of olaparib and ATR / CHK1 kinase inhibitors as a targeted anti-cancer therapy based on synthetic lethality

Principal investigator: dr hab. Aneta Katarzyna Rogalska

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: SONATA BIS 9, Panel: NZ7

76. Multitarget approach to break the vicious circle of tau pathology and neuroinflammation in Alzheimer's disease: developm…

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA BIS 9, Panel: NZ7

77. Deciphering molecular mechanism of CDK8 kinase inhibitors action in acute myeloid leukemia

Principal investigator: dr hab. Michał Marek Mikula

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Call: SONATA BIS 8, Panel: NZ2

78. Role of histone H3 serine 10 (H3S10) kinases in deregulation of transcription in diffuse large B-cell lymphoma

Principal investigator: prof. Przemysław Juszczyński

Instytut Hematologii i Transfuzjologii

Call: OPUS 15, Panel: NZ5

79. Role of the lysosomes in insulin-dependent regulation of AMP-ativated protein kinase expression and activity in podocyte…

Principal investigator: Patrycja Rachubik

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 15, Panel: NZ4

80. The role of glycogen synthase kinase 3 (GSK-3) in activation p53 and the TREM2 signaling pathway

Principal investigator: dr Barbara Małgorzata Łasut-Szyszka

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Call: PRELUDIUM 14, Panel: NZ5

81. Regulation of alternative Dclk1 kinase gene isoforms by psychotropic drugs

Principal investigator: Magdalena Agata Zygmunt

Instytut Farmakologii PAN

Call: PRELUDIUM 12, Panel: NZ3

82. Use of novel small molecule inhibitors of PERK kinase dependent UPR pathway for the colorectal cancer treatment

Principal investigator: prof. Adam Janusz Dziki

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 12, Panel: NZ5

83. Impact of palmitoylation on the Zn(II)-dependent interaction between CD4 coreceptor and Lck tyrosine kinase.

Principal investigator: Anna Marta Kocyła

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: PRELUDIUM 11, Panel: NZ1

84. mTOR kinase impact on cellular functions of selected molecular motors

Principal investigator: prof. Jacek Ryszard Jaworski

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 11, Panel: NZ3

85. Use of novel small molecule inhibitors of PERK kinase dependent UPR pathway for the primary open-angle glaucoma treatmen…

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 11, Panel: NZ5

86. Synthesis of new glutamate receptors antagonists and extensive investigation of their effect on tumor cells in the prese…

Principal investigator: prof. Maria Wanda Bretner

Politechnika Warszawska, Wydział Chemiczny

Call: OPUS 9, Panel: ST5

87. New MOF compounds as degradable nanocontainers of tyrosine kinases inhibitors in novel anti-cancer therapy

Principal investigator: prof. Artur Piotr Terzyk

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: OPUS 9, Panel: ST5

88. Studies on the influence of selected inhibitors of kinases involved in signaling pathways in tumor cells on NK cell cyto…

Principal investigator: Marta Siernicka

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Call: PRELUDIUM 7, Panel: NZ6

89. Molecular mechanisms of cell death evoked by a monoclonal antibody binding to GD2 ganglioside expressed on human neurobl…

Principal investigator: prof. Hanna Barbara Rokita

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 4, Panel: NZ1

90. Regulation of mTOR kinase signaling pathway by ESCRT-II complex in dendritogenesis.

Principal investigator: Marcelina Pieprzyk

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: PRELUDIUM 4, Panel: NZ3

91. The role of sirtuins and AMPK protein kinase in insulin resistance of podocytes

Principal investigator: dr Dorota Rogacka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: OPUS 3, Panel: NZ5

92. Regulation of clathrin-dependent endocytosis by mTOR kinase in neuronal development

Principal investigator: prof. Jacek Ryszard Jaworski

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 2, Panel: NZ3

93. Defining the mechanism of GSK3 dependent regulation of mTOR kinase activity in neurons in physiology and pathology.

Principal investigator: Małgorzata Barbara Urbańska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: PRELUDIUM 1, Panel: NZ3

94. Wall associated kinases in wheat and barley - the novel group of genes involved in resistance against pathogens

Principal investigator: prof. Wacław Marian Orczyk

Instytut Hodowli i Aklimatyzacji Roślin - Państwowy Instytut Badawczy

Call: OPUS 1, Panel: NZ9

95. Genomewide extracellular signal-regulated kinase (ERK) pathway components interaction with human genome

Principal investigator: dr Michał Mikula

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Call: SONATA 1, Panel: NZ2

96. Normal021falsefalsefalseMicrosoftInternetExplorer4/* Style Definitions */table.MsoNormalTable{mso-style-name:Standardowy…

Principal investigator: dr Maciej Suski

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: PRELUDIUM 1, Panel: NZ2

97. MAP kinase signaling pathway in response to replication stress and DNA damage in root meristem cells of Vicia faba

Principal investigator: Konrad Szczepan Winnicki

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska; Katedra Cytofizjologii

Call: PRELUDIUM 1, Panel: NZ3

98. Jasmonic acid biosynthesis enviromental regulation through mitogen-activated protein kinases in Arabidopsis thaliana.

Principal investigator: dr Łukasz Gałgański

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: SONATA 1, Panel: NZ3

99. Unraveling mechanisms and physiological outcome of lipid-evoked regulation of proteostasis in the intestine.

Principal investigator: dr hab. Grzegorz Piotr Sumara

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 23, Panel: NZ4

100. A double whammy for the NF-κB signalling pathway: development of TAK1 and IKKβ degraders against inflammation-driven dis…

Principal investigator: dr hab. Anna Karolina Więckowska

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 24 (LAP), Panel: NZ7

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