Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of the lysosomes in insulin-dependent regulation of AMP-ativated protein kinase expression and activity in podocytes. Influence on filtration barrier permeability.

2018/29/N/NZ4/02212

Keywords:

podocyte insulin lysosome lysosomal complex axin AMPK

Descriptors:

  • NZ1_1: Molecular biology
  • NZ3_1: Cell biology
  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Patrycja Rachubik 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 139 500 PLN

Project start date (Y-m-d): 2019-01-24

Project end date (Y-m-d): 2023-01-23

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Inkubator CO2 (25 500 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Involvement of Axin1 and AMPK in the regulation of insulin-stimulated glucose uptake and lysosome activity in cultured rat podocytes
    Authors:
    Rachubik Patrycja, Rogacka Dorota, Audzeyenka Irena, Wysocka Magdalena, Typiak Marlena, Piwkowska Agnieszka
    Academic press:
    Journal of Cellular Physiology , Wydawca: Wiley
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Role of lysosomes in insulin signaling and glucose uptake in cultured rat podocytes
    Authors:
    Rachubik Patrycja, Rogacka Dorota, Audzeyenka Irena, Typiak Marlena, Wysocka Magdalena, Szrejder Maria, Lesner Adam, Piwkowska Agnieszka
    Academic press:
    Biochemical and Biophysical Research Communications (rok: 2023, tom: 679, strony: 145-159), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.bbrc.2023.09.012. - link to the publication
  1. The role of Axin1 in the insulin-dependentregulation of glucose uptake in cultured rat podocytes
    Authors:
    Patrycja Rachubik, Dorota Rogacka, Irena Audzeyenka, Agnieszka Piwkowska
    Conference:
    5th Congress of Polish Biosciences BIO2023 "Different faces of biosciences" (rok: 2023, ), Wydawca: Acta Biochimica Polonica
    Data:
    konferencja 13-16.09
    Status:
    Published
    DOI:
    link to the publication

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