Search results

1. Regulacja procesu deoksyhypuzynacji przez kinazy białkowe

Principal investigator: Paweł Kochanowski

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Call: PRELUDIUM 22, Panel: NZ1

2. The role of SnRK2 kinases in plant response to environmental stresses. The interplay between SnRK2 kinases, PP2C phospha…

Principal investigator: prof. Grażyna Anna Dobrowolska

Instytut Biochemii i Biofizyki PAN

Call: OPUS 2, Panel: NZ3

3. Human exosomes as natural carriers of protein kinase CK2 inhibitors and degraders in targeted anticancer therapy.

Principal investigator: dr hab. Patrycja Joanna Wińska

Politechnika Warszawska

Call: OPUS 28 (LAP), Panel: NZ5

4. How activation of the Mec1/Tel1 kinase (human ATR/ATM) pathway in response to the nuclear genome damage influences the s…

Principal investigator: dr Aneta Edyta Kaniak-Golik

Instytut Biochemii i Biofizyki PAN

Call: OPUS 13, Panel: NZ3

5. New opportunities for use of PERK kinase inhibitors in eIF2alfa factor-dependant signalling pathway in antitumor therapy

Principal investigator: dr Wioletta Julia Rozpędek-Kamińska

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 10, Panel: NZ3

6. Kinases of emerging relevance in cancer - structural characterization.

Principal investigator: dr Grzegorz Dubin

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: SONATA BIS 2, Panel: NZ1

7. The impact of S6K1 and S6K2 kinases on the efficiency of lysosomal degradation of cellular structures

Principal investigator: dr Aleksandra Agata Hać

Uniwersytet Gdański, Wydział Biologii

Call: PRELUDIUM 3, Panel: NZ3

8. Identification of the regulon and interactome of orphan histidine kinase in Streptomyces coelicolor A3(2)

Principal investigator: Mateusz Wenecki

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Call: PRELUDIUM 24, Panel: NZ2

9. Graphene Oxide-Immobilized Adenylate Kinase as a Molecular Mediator of Vascular Homeostasis

Principal investigator: Agata Wikarska

Uniwersytet Mikołaja Kopernika

Call: PRELUDIUM 24, Panel: NZ1

10. Analysis of pharmacokinetic, pharmacodynamic and molecular determinants of intolerance and resistance to the Janus kinas…

Principal investigator: prof. Marta Katarzyna Karaźniewicz-Łada

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: OPUS 27, Panel: NZ7

11. Regulatory role of the N-terminal fragment of diacylglycerol kinase-ε and its contribution to the pro-inflammatory respo…

Principal investigator: Gabriela Traczyk

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: PRELUDIUM 23, Panel: NZ3

12. The role of nuclear kinases in the regulation of Arabidopsis thaliana FEN1 nuclease

Principal investigator: dr hab. Wojciech Kazimierz Strzałka

Uniwersytet Jagielloński

Call: OPUS 27, Panel: NZ3

13. Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu…

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Call: OPUS 26, Panel: NZ7

14. Novel aspects of the mechanisms of vascular toxicity of tyrosine kinase inhibitors: studies on their proinflammatory act…

Principal investigator: dr Tomasz Krzysztof Prajsnar

Uniwersytet Jagielloński, Wydział Biologii

Call: OPUS 26, Panel: NZ5

15. Exploring kinase hyperactivation as an innovative approach for chemo-immunotherapy for B cell acute lymphoblastic leukem…

Principal investigator: dr hab. Małgorzata Firczuk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM BIS 5, Panel: NZ7

16. Investigating the mechanisms of CD20 downregulation triggered by tyrosine kinase inhibitors in Philadelphia chromosome-p…

Principal investigator: Krzysztof Domka

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 22, Panel: NZ5

17. The potassium puzzle: unraveling the connection between the potassium channel and lipid kinases in kidney functioning

Principal investigator: dr hab. Piotr Rajmund Koprowski

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 25, Panel: NZ1

18. Dissecting the regulatory interplay between proteases and protein kinases in acute lymphoblastic leukemia using mass cyt…

Principal investigator: dr hab. Marcin Łukasz Poręba

Politechnika Wrocławska

Call: OPUS 24, Panel: NZ5

19. Effects of tyrosine kinase inhibitors on Syk pathway in eNOS-based platelet subpopulations and on endothelial barrier in…

Principal investigator: dr hab. Aneta Iwona Radziwon-Balicka

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: POLONEZ BIS 3, Panel: NZ7

20. Role of RelA(p65) and cRel phosphorylations and their kinases in the biology of Diffuse-large B-cell lymphoma and Hodgki…

Principal investigator: dr Maciej Stefan Szydłowski

Instytut Hematologii i Transfuzjologii

Call: OPUS 22, Panel: NZ5

21. Investigating the role of the focal adhesion kinase and its related signaling pathways in glucocorticoid- and stress-ind…

Principal investigator: Michał Józef Wilczkowski

Instytut Farmakologii PAN

Call: PRELUDIUM 20, Panel: NZ4

22. Iron chelators as tyrosine kinase inhibitors - a new strategy for the treatment of glioblastoma multiforme

Principal investigator: dr hab. Anna Dominika Mrozek-Wilczkiewicz

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Call: PRELUDIUM BIS 2, Panel: NZ5

23. Towards innovative strategy for treatment of Alzheimer's Disease via dual inhibition of receptor 5-HT6 and kinase CDK5.

Principal investigator: Sylwia Sudoł-Tałaj

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 19, Panel: NZ7

24. The proangiogenic functions of PIM kinases in plasma cell myeloma

Principal investigator: Filip Aleksander Garbicz

Instytut Hematologii i Transfuzjologii

Call: ETIUDA 8, Panel: NZ5

25. Determination of the role of present in extracelluar space integrin-linked kinase (ILK) in adhesion, migration/invasion …

Principal investigator: dr hab. Antonina Joanna Mazur

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: PRELUDIUM BIS 1, Panel: NZ3

26. Comprehensive bioinformatic analysis of known and novel human microbiome kinases and pseudokinases.

Principal investigator: dr Marcin Tomasz Gradowski

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Call: PRELUDIUM 18, Panel: NZ2

27. Comparative evaluation of effects of tyrosine kinase inhibitors (TKIs) on endothelial function in vivo in mice

Principal investigator: Brygida Elżbieta Marczyk

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Call: PRELUDIUM 17, Panel: NZ5

28. The role of PIM kinases in the vascular niche of multiple myeloma

Principal investigator: Filip Aleksander Garbicz

Instytut Hematologii i Transfuzjologii

Call: PRELUDIUM 16, Panel: NZ5

29. Regulation of carnitine transporters secretory pathway by AKT - a kinase hyperactivated in cancer cells

Principal investigator: prof. Katarzyna Anna Nałęcz

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 16, Panel: NZ3

30. Modeling phosphorylation by human thymidine kinase 1. A crucial step in the rational design of thymidine-analogue radios…

Principal investigator: dr Samanta Kinga Romanowska

Uniwersytet Gdański, Wydział Chemii

Call: PRELUDIUM 15, Panel: ST4

31. The role of diacylglycerol kinase epsilon, an enzyme of the phosphatidylinositol cycle, in the regulation of LPS-induced…

Principal investigator: prof. Katarzyna Kwiatkowska

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 15, Panel: NZ3

32. SnRK2 protein kinases as integrators of environmental signals in the regulation of the senescence in plants

Principal investigator: dr Anna Marta Kulik

Instytut Biochemii i Biofizyki PAN

Call: OPUS 14, Panel: NZ3

33. Role of PIM kinases in the biology of classical Hodgkin lymphoma tumor-associated macrophages

Principal investigator: dr Maciej Stefan Szydłowski

Instytut Hematologii i Transfuzjologii

Call: SONATA 13, Panel: NZ5

34. Role of a protein kinase-like effector HopBF1 in virulence of bacterial pathogens.

Principal investigator: dr hab. Magdalena Krzymowska

Instytut Biochemii i Biofizyki PAN

Call: OPUS 13, Panel: NZ1

35. Design of new small molecular regulators (inhibitors, activators) of the catalytic activity of adenylate kinases. Molecu…

Principal investigator: dr Anna Kozakiewicz-Piekarz

Uniwersytet Mikołaja Kopernika, Wydział Chemii

Call: OPUS 13, Panel: ST4

36. Anaplastic Lymphoma Kinase (ALK) Overexpression as a Prognostic and Predictive Factor in Serous Ovarian Carcinoma

Principal investigator: Adam Stanisław Gorczyński

Gdański Uniwersytet Medyczny, Wydział Lekarski

Call: PRELUDIUM 13, Panel: NZ4

37. Protein kinase B signalling pathway in glioblastoma cells transfected with sequence encoding liver-type glutaminase (GAB…

Principal investigator: Ewelina Julia Majewska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 12, Panel: NZ5

38. Insights into biological activity and mechanism of action of novel styrylquinazoline derivatives as tyrosine kinase inhi…

Principal investigator: Katarzyna Anna Malarz

UNIWERSYTET ŚLĄSKI, Wydział Matematyki, Fizyki i Chemii

Call: PRELUDIUM 12, Panel: NZ7

39. The role of SnRK2 kinases in regulation of pre-mRNA alternative splicing and miRNA biogenesis in plants response to sali…

Principal investigator: dr hab. Grażyna Anna Dobrowolska

Instytut Biochemii i Biofizyki PAN

Call: OPUS 12, Panel: NZ3

40. Molecular identification of signalling pathways activated by receptor kinase CRK5 during senescence and stress response …

Principal investigator: dr Paweł Burdiak

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Call: SONATA 12, Panel: NZ1

41. Evaluation of the impact of sphingosine kinase type 1 and 2 activity on the pharmacological mobilization of hematopoieti…

Principal investigator: Mateusz Stanisław Adamiak

Warszawski Uniwersytet Medyczny, II Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim oraz Oddziałem Fizjoterapii

Call: PRELUDIUM 12, Panel: NZ4

42. Sphingosine kinase 1 as a modulator of vascular function - mechanisms and therapeutical opportunities

Principal investigator: dr hab. Mateusz Siedliński

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: SONATA BIS 6, Panel: NZ4

43. Analysis of the effectiveness of anticancer activity of tyrosine kinase inhibitors combined with nanoparticles in in vit…

Principal investigator: dr Natalia Piergies

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego PAN

Call: SONATA 11, Panel: ST4

44. Significance of PIM-1 kinase mutations in progression of chronic lymphocytic leukemia

Principal investigator: dr Bartosz Puła

Instytut Hematologii i Transfuzjologii

Call: SONATA 11, Panel: NZ5

45. Mitochondrial nucleoside diphosphate kinase (NDPK) as a regulator of mitochondrial proton leak catalyzed by purine nucle…

Principal investigator: dr hab. Andrzej Marek Woyda-Płoszczyca

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: SONATA 10, Panel: NZ3

46. Understanding the mechanism of ubiquitin-mediated proteolysis of the MAPKKK18 kinase

Principal investigator: Małgorzata Tajdel-Zielińska

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 9, Panel: NZ3

47. The role of WAKs (Wall-Associated Kinases) in perception of pectin-related signal of Zn level in apoplast

Principal investigator: Aleksandra Anna Weremczuk

Uniwersytet Warszawski, Wydział Biologii

Call: PRELUDIUM 9, Panel: NZ3

48. Biological function of the evolutionarily conserved kinase SELO, common to most living organisms - study in bacterial an…

Principal investigator: dr hab. Krzysztof Piotr Pawłowski

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Rolnictwa i Biologii

Call: OPUS 8, Panel: NZ1

49. The functional meaning of the protein kinase C beta (PKC beta) translocation due to cerebral ischemia. Solving the puzzl…

Principal investigator: dr Małgorzata Beręsewicz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 8, Panel: NZ3

50. Role of protein kinase G type I alpha in the regulation of filtration barrier in glomerular dysfunction.

Principal investigator: dr hab. Agnieszka Piwkowska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA BIS 4, Panel: NZ4

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