Projects funded by the NCN
Impact of palmitoylation on the Zn(II)-dependent interaction between CD4 coreceptor and Lck tyrosine kinase.
2016/21/N/NZ1/02775
Keywords:
zinc CD4 Lck palmitoylation lipid rafts T cell receptor
Descriptors:
- NZ1_3: Biophysics
- NZ1_1: Molecular biology
- NZ1_2: Biochemistry
Panel:
NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology
Host institution :
Uniwersytet Wrocławski, Wydział Biotechnologii
woj. dolnośląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 11 - announced on 2016-03-15
Amount awarded: 99 600 PLN
Project start date (Y-m-d): 2017-03-09
Project end date (Y-m-d): 2019-12-08
Project duration:: 33 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Laptop (3 000 PLN)
Information in the final report
- Publication in academic press/journals (2)
- Galvanization of Protein-Protein Interactions in a Dynamic Zinc InteractomeAuthors:Anna Kocyła, Józef Ba Tran, Artur KrężelAcademic press:Trends in Biochemical Sciences (rok: 2021, tom: 46, strony: 64-79), Wydawca: Cell PressStatus:PublishedDOI:10.1016/j.tibs.2020.08.011 - link to the publication
- A combined biochemical and cellular approach reveals Zn2+-dependent hetero- and homodimeric CD4 and Lck assemblies in T cellsAuthors:Anna M. Kocyła, Aleksander Czogalla, Inga Wessels, Lothar Rink, Artur KrężelAcademic press:Structure (rok: 2024, tom: 32, strony: 45303), Wydawca: Cell PressStatus:PublishedDOI:10.1016/j.str.2023.11.013 - link to the publication