Projects funded by the NCN
Studies on the influence of selected inhibitors of kinases involved in signaling pathways in tumor cells on NK cell cytotoxicity
2014/13/N/NZ6/02081
Keywords:
NK cells monoclonal antibodes ADCC cell signaling inhibitors
Descriptors:
- NZ6_8: Other related subjects
- NZ6_2: Clinical immunology
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Warszawski Uniwersytet Medyczny, I Wydział Lekarski
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 7 - announced on 2014-03-17
Amount awarded: 149 968 PLN
Project start date (Y-m-d): 2015-02-18
Project end date (Y-m-d): 2018-02-17
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (2)
- Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors.Authors:Oei Vincent Yi Sheng, Siernicka Marta, Graczyk-Jarzynka Agnieszka, Hoel Hanna Julie, Yang Weiwen, Palacios Daniel, Almåsbak Hilde, Bajor Malgorzata, Clement Dennis, Brandt Ludwig, Önfelt Björn, Goodridge Jodie, Winiarska Magdalena, Zagozdzon Radoslaw, Olweus Johanna, Kyte Jon-Amund, Malmberg Karl-JohanAcademic press:Cancer Immunology Research (rok: 2018, tom: 6(4), strony: 467-480), Wydawca: AACR American Association for Cancer ResearchStatus:PublishedDOI:10.1158/2326-6066.CIR-17-0207 - link to the publication
- Adenanthin, a new inhibitor of thiol-dependent antioxidant enzymes, impairs the effector functions of human natural killer cells.Authors:Siernicka Marta, Winiarska Magdalena, Bajor Małgorzata, Firczuk Małgorzata, Muchowicz Angelika, Bobrowicz Małgorzata, Fauriat Cyril, Gołąb Jakub, Olive Daniel, Zagożdżon RadosławAcademic press:Immunology (rok: 2015, tom: 146(1), strony: 173-183), Wydawca: John Wiley & SonsStatus:PublishedDOI:10.1111/imm.12494 - link to the publication