The role of sirtuins and AMPK protein kinase in insulin resistance of podocytes

2012/05/B/NZ5/01448

Keywords

Descriptors

  • NZ3_2: Fizjologia komórki
  • NZ1_1: Biologia molekularna
  • NZ5_3: Patogeneza chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Dorota Rogacka

Number of co-investigators in the project: 5

Call

OPUS 3 – announced on 2012-03-15

Amount awarded
580 350 PLN
Project start date
2013-02-11
Project end date
2016-02-10
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Licznik scyntylacyjny. Cost: 230 000 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Involvement of the AMPK-PTEN pathway in insulin resistance induced by high glucose in cultured rat podocytes.

    Authors:
    Dorota Rogacka, Agnieszka Piwkowska, Irena Audzeyenka, Stefan Angielski, Maciej Jankowski
    Academic press:
    The International Journal of Biochemistry & Cell Biology (year: 2014, volume: 51, pages: 120-130), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biocel.2014.04.008. – link to the publication
  2. SIRT1-AMPK crosstalk is involved in high glucose-dependent impairment of insulin responsiveness in primary rat podocytes

    Authors:
    Dorota Rogacka, Agnieszka Piwkowska, Irena Audzeyenka, Stefan Angielski, Maciej Jankowski
    Academic press:
    Experimental Cell Research (year: 2016, volume: 349, pages: 328-338), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.yexcr.2016.11.005 – link to the publication

Articles in post-conference publications (1)

  1. The Role of AMPK-SIRT1 Pathway in High Glucose-Induced Insulin Resistance in Rat Cultured Podocytes

    Authors:
    Dorota Rogacka, Agnieszka Piwkowska, Irena Audzeyenka, Stefan Angielski, Maciej Jankowski
    Conference:
    Experimental Biology (year: 2015, pages: 0,0312314814814815), Publisher: The Federation of American Societies for Experimental Biology
    Date:
    conference 28 marca - 1 kwietnia
    Status:
    Published
    DOI:
    link to the publication

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