Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Analysis of immune responses of rats after vaccination with cDNA encoding Fasciola hepatica phosphoglycerate kinase and subsequent challenge infection with liver fluke's metacercariae.

2011/01/N/NZ6/00892

Keywords:

Fasciola hepatica DNA vaccination phosphoglycerate kinase immune response

Descriptors:

  • NZ6_3: Animal immunology
  • NZ6_6: Parasitology
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Parazytologii im. Witolda Stefańskiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agnieszka Wesołowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 196 800 PLN

Project start date (Y-m-d): 2011-12-12

Project end date (Y-m-d): 2014-04-11

Project duration:: 28 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. komora wentylowana UNIPROTECT do przechowywania zwierząt laboratoryjnych (70 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Lymphocyte responses of rats vaccinated with cDNA encoding a phosphoglycerate kinase of Fasciola hepatica (FhPGK) and F. hepatica infection.
    Authors:
    Agnieszka Wesołowska, Anna Zawistowska-Deniziak, Luke J. Norbury, Przemysław Wilkowski, Kamil Januszkiewicz, Anna M. Pyziel, Wojciech Zygner
    Academic press:
    Parasite Immunology (rok: 2015, tom: nie dotyczy, strony: nie dotyczy), Wydawca: John Wiley & Sons Ltd
    Status:
    Submitted
    DOI:
    nie - link to the publication
  2. Immune responses in rats and sheep induced by a DNA vaccine containing the phosphoglycerate kinase gene of Fasciola hepatica and liver fluke infection.
    Authors:
    Agnieszka Wesołowska, Anna Zawistowska-Deniziak, Luke J. Norbury, Przemysław Wilkowski, Kamil Januszkiewicz, Anna M. Pyziel, Wojciech Zygner, Halina Wędrychowicz
    Academic press:
    Acta Parasitologica (rok: 2015, tom: nie dotyczy, strony: nie dotyczy), Wydawca: DeGruyter
    Status:
    Accepted for publication
    DOI:
    nie - link to the publication
  1. Evaluation of the cellular immune response of male and female rats vaccinated with cDNA encoding a phosphoglycerate kinase of Fasciola hepatica (cDNA-FhPGK).
    Authors:
    Wesolowska A., Zawistowska-Deniziak A., Norbury L.J., Wilkowski P., Januszkiewicz K., Pyziel A., Zygner W., Wędrychowicz H.
    Conference:
    The XXIIIth Congress of the Polish Parasitological Society (rok: 2013, ), Wydawca: Annales of Parasitology
    Data:
    konferencja 4-7 wrzesień 2013
    Status:
    Published
  2. Study of the local immune response in the peritoneal fluid and lymph nodes of rats vaccinated with cDNAencoding a phosphoglycerate kinase of Fasciola hepatica (cDNA-FhPGK).
    Authors:
    Wesolowska A., Zawistowska-Deniziak A., Norbury L.J., Wilkowski P., Januszkiewicz K., Pyziel A., Zygner W., Wędrychowicz H.
    Conference:
    The XXIIIth Congress of the Polish Parasitological Society (rok: 2013, ), Wydawca: Annales of Parasitology
    Data:
    konferencja 4-7 wrzesień 2014
    Status:
    Published

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