Projects funded by the NCN

In the search of specific oxylipin fingerprint reflecting the development of endothelial dysfunction with the use of non...

Call: SONATA 17 , Panel: NZ5

Principal investigator: dr Agnieszka Kij

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The assessment of the susceptibility of the lung endothelium to infections with respiratory viruses and its involvement ...

Call: OPUS 22 , Panel: NZ5

Principal investigator: dr hab. Maciej Chałubiński

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Keap1-dependent proteopathy as a unifying mechanism of vascular dysfunction

Call: OPUS 22 , Panel: NZ4

Principal investigator: dr hab. Anna Grochot-Przęczek

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Role of endothelial cells in development of post-inflammatory dilated cardiomyopathy

Call: PRELUDIUM BIS 3 , Panel: NZ5

Principal investigator: dr hab. Przemysław Błyszczuk

Uniwersytet Jagielloński, Collegium Medicum

Multimodal approach for a comprehensive assessment of (dys)functional endothelial phenotype in isolated blood vessels

Call: SONATA 17 , Panel: ST4

Principal investigator: dr Marta Pacia

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Metabolic reprogramming in age-dependent endothelial dysfunction and vascular stiffness; novel mechanism of 'inflamm-age...

Call: MAESTRO 13 , Panel: NZ4

Principal investigator: prof. Stefan Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

How mutations in the dystrophin-encoding gene affect calcium homeostasis, energy metabolism and selected functions of va...

Call: OPUS 21 , Panel: NZ5

Principal investigator: prof. Krzysztof Zabłocki

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

PDMS-based specially designed microfluidic channel lined with primary endothelial cells: a novel tool for experimental p...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Stefano Rocchetti

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Assessment of the endothelial adherens junctions, neuronal damage and the fetal blood-brain barrier integrity in respons...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Natalia Misan

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The role of rhinovirus in the limitation of infection of the human lung endothelium with low pathogenic coronavirus in t...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Mateusz Gawrysiak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Breast cancer metastasis-induced endothelial-mesenchymal transition alongside ageing; implications for therapy

Call: OPUS 21 , Panel: NZ5

Principal investigator: dr Marta Smęda

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Early and late consequences of stem cell compartment damage due to SARS-CoV-2 infection

Call: OPUS 21 , Panel: NZ6

Principal investigator: prof. Magdalena Kucia

Warszawski Uniwersytet Medyczny

The role of lactate dehydrogenase A in development of endothelial dysfunction in murine model of heart failure

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: Agnieszka Karaś

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Enhancement of heart repair after myocardial infarction by means of genetically improved cardiomyocytes and endothelial ...

Call: SHENG 2 , Panel: NZ3

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński

Importance of fatty acids and their transporters for placenta development in the pig

Call: OPUS 20 , Panel: NZ9

Principal investigator: prof. Agnieszka Blitek

Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

Identify molecules and mechanisms by which all-trans retinoic acid-induced browning of perivascular adipose tissue regul...

Call: SONATA 16 , Panel: NZ5

Principal investigator: dr Małgorzata Kalisz

Centrum Medyczne Kształcenia Podyplomowego

LDL-mimetic liposomal contrast agent for MRI-based detection of increased endothelial permeability in the early phase of...

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr Anna Bar

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Vascular endothelium-supporting materials: Understanding the structural and physicochemical requirements

Call: OPUS 20 (LAP) , Panel: ST5

Principal investigator: prof. Tomasz Ciach

Politechnika Warszawska

Microenvironment in differentiation and maturation of human pancreatic endocrine cells

Call: OPUS 20 , Panel: NZ3

Principal investigator: dr hab. Małgorzata Borowiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Molecular background of microvascular complications in HNF1A-MODY patients: induced pluripotent stem cells as disease mo...

Call: SONATA BIS 10 , Panel: NZ3

Principal investigator: dr Neli Kachamakova-Trojanowska

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Spectroscopic and microscopic techniques in nano-probing, modeling and recognition of interactions between erythrocytes ...

Call: SONATA BIS 10 , Panel: ST4

Principal investigator: dr hab. Katarzyna Marzec

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Novel strategies for pharmacological modulation of platelet-derived microparticles - effects on endothelium

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Agnieszka Pełesz

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The proangiogenic functions of PIM kinases in plasma cell myeloma

Call: ETIUDA 8 , Panel: NZ5

Principal investigator: Filip Garbicz

Instytut Hematologii i Transfuzjologii

Which patients with rheumatoid arthritis or axial spondyloarthritis without classical cardiovascular risk factors have m...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Jarosław Nowakowski

Uniwersytet Jagielloński, Collegium Medicum

Gamma-glutamylcysteine ligase participation in the antioxidant mechanism of action of sulodexide on vascular endothelial...

Call: PRELUDIUM 18 , Panel: NZ7

Principal investigator: Klaudia Bontor

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

In search of spectroscopic markers of autophagy based on pharmacologically induced phospholipidosis in endothelial cells

Call: PRELUDIUM 18 , Panel: ST4

Principal investigator: Ewelina Bik

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The effect of anoxia/reoxygenation on the bioenergetic properties of mitochondria isolated from endothelial cells cultur...

Call: PRELUDIUM 18 , Panel: NZ1

Principal investigator: Karolina Dominiak

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Function and phenotype of liver sinusoidal endothelial cells (LSECs) and their role in liver dysfunction development in ...

Call: PRELUDIUM 18 , Panel: NZ5

Principal investigator: Kamila Wojnar-Lasoń

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

DHA/EPA and changes of peripheral blood cell epigenetics as well as the level of endothelial and pancreatic beta cell sp...

Call: MAESTRO 1 , Panel: NZ2

Principal investigator: prof. Aldona Dembińska-Kieć

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydzial Lekarski

From the structure of fenestrations in live Liver Sinusoidal Endothelial Cells to real-time in vitro pharmacology

Call: SONATA 15 , Panel: NZ3

Principal investigator: dr Bartłomiej Zapotoczny

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

Ecto-enzymes in interactions of vascular endothelium with blood circulating cells in physiology, pathology and therapy; ...

Call: SONATA 15 , Panel: NZ3

Principal investigator: dr Barbara Kutryb-Zając

Gdański Uniwersytet Medyczny, Wydział Lekarski

Comparative evaluation of effects of tyrosine kinase inhibitors (TKIs) on endothelial function in vivo in mice

Call: PRELUDIUM 17 , Panel: NZ5

Principal investigator: Brygida Marczyk

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The assessment of cysteinyl leukotriene receptor antagonist role in inhibition of atherosclerosis, proliferation and its...

Call: OPUS 17 , Panel: NZ5

Principal investigator: dr hab. Paweł Maga

Uniwersytet Jagielloński, Collegium Medicum

The role of molecular composition of endothelial and pancreatic beta-cell extracellular vesicle in diabetic endothelial ...

Call: OPUS 17 , Panel: NZ3

Principal investigator: dr hab. Ewa Stępień

Uniwersytet Jagielloński

Quantitative assessment of vascular endothelial growth factor (VEGF) in serum, follicular fluid (FF) and VEGF mRNA in gr...

Call: OPUS 1 , Panel: NZ5

Principal investigator: prof. Artur Jakimiuk

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Cellular mechanisms and effects in vivo of selective lactate dehydrogenase A inhibitors in experimental models of mesoth...

Call: OPUS 16 , Panel: NZ7

Principal investigator: prof. Ryszard Smoleński

Gdański Uniwersytet Medyczny, Wydział Lekarski

Glycocalyx damage - the first stage of pathomechanism of endothelial dysfunction; measurements using capillary electroph...

Call: PRELUDIUM 16 , Panel: NZ7

Principal investigator: dr Karolina Matyjaszczyk-Gwarda

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Ectosomal alpha-v beta-3 and alpha-v beta-5 as potential proangiogenic factors during melanoma progression

Call: PRELUDIUM 16 , Panel: NZ4

Principal investigator: dr Magdalena Surman

Uniwersytet Jagielloński, Wydział Biologii

Characterization of two novel proteases from the human periodontopathogen Tannerella forsythia

Call: PRELUDIUM 16 , Panel: NZ1

Principal investigator: Irena Waligórska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Endothelial cells in the composition of hematopoietic niche: the versatile choir or specialized soloists?

Call: MAESTRO 10 , Panel: NZ3

Principal investigator: prof. Alicja Józkowicz

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Nutrition, epigenetics and disease - Effects of a ketogenic diet and beta-hydroxybutyrate on crucial epigenetic signatur...

Call: HARMONIA 10 , Panel: NZ3

Principal investigator: dr hab. Aneta Balcerczyk

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Mechanistic links between psoriasis and cardiovascular complications: investigation on inflammation induced alterations ...

Call: SONATA BIS 8 , Panel: NZ5

Principal investigator: dr hab. Monika Biniecka

Uniwersytet Jagielloński

Molecular mechanisms of heart failure in Duchenne and Becker muscular dystrophy

Call: MAESTRO 10 , Panel: NZ3

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Role of angiotensin 1-12 and ACE-independent generation of Angiotensin II in peripheral endothelial dysfunction in heart...

Call: PRELUDIUM 15 , Panel: NZ4

Principal investigator: Tasnim Mohaissen

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

Towards novel mechanisms of endothelial dysfunction in E3L.CETP mice displaying hyperlipidaemia with human-like lipoprot...

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Stefan Chłopicki

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

The assesment of endothelium considering role of endothelial progenitor cells and leukotrienes synthesis in patients wit...

Call: PRELUDIUM 14 , Panel: NZ5

Principal investigator: Agnieszka Wachsmann

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

The role of Mcpip1 RNase in disrupted endothalial homeostasis accompanying nonalcoholic fatty liver disease.

Call: OPUS 14 , Panel: NZ5

Principal investigator: dr Jerzy Kotlinowski

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Development of a hybrid model bioreactor to study the effect of variable glucose concentration on metabolism and oxidati...

Call: OPUS 14 , Panel: ST7

Principal investigator: dr hab. Piotr Ładyżyński

Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza Polskiej Akademii Nauk

Peritoneal dialysis biocompatibility - peritoneal mesothelium - arterial endothelium

Call: OPUS 14 , Panel: NZ4

Principal investigator: prof. Andrzej Bręborowicz

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Raman spectroscopy in in studies on uptake of molecules by liver sinusoidal endothelial cells in vitro

Call: PRELUDIUM 14 , Panel: ST4

Principal investigator: dr Ewelina Matuszyk

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)