Projects funded by the NCN

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261 projects found matching your search criteria :

  1. Bionanoparticles with a molecular targeting device as a weapon for breast cancer

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sylwia Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  2. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Kiliszek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  3. Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sławomir Filipek

    Uniwersytet Warszawski, Wydział Chemii

  4. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Przepiórska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  5. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Magdalena Białoń

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  6. The application of artificial intelligence to the discovery of new natural drugs with mechanisms aimed at lowering free ...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Maciej Spiegel

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny

  7. PFAS exposure and premature ovarian insufficiency: molecular mechanism.

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Anna Ptak

    Uniwersytet Jagielloński, Wydział Biologii

  8. Enhancement of antidepressant therapy by combined administration of hyperforin and ketamine: behavioral and molecular st...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Bartłomiej Pochwat

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  9. Understanding the molecular and ecological interactions between viruses and eriophyoid mites

    Call: POLONEZ BIS 1 , Panel: NZ9

    Principal investigator: dr Tobiasz Druciarek

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie

  10. Brain GABAB receptors as determinants of obesity phenotypes: evaluation of adolescent female and male rats

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: prof. Małgorzata Filip

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  11. Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Papaj

    Politechnika Śląska, Centrum Biotechnologii

  12. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  13. New post-treatment strategy against stroke and perinatal asphyxia – a novel approach based on a selective activation of ...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Agnieszka Wnuk

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  14. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  15. Photoswitchable and chimeric molecules for spatially restricted and endoplasmic reticulum-specific blockade of PD-L1 pro...

    Call: SONATA BIS 11 , Panel: NZ7

    Principal investigator: dr Łukasz Skalniak

    Uniwersytet Jagielloński, Wydział Chemii

  16. New graphene-based approach targeting the prion-like propagation of α-synuclein in Parkinson's disease.

    Call: SONATA BIS 11 , Panel: NZ7

    Principal investigator: dr hab. Małgorzata Kujawska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  17. Identification of breast cancer cells death and senescence mechanisms induction resulting from telomerase silencing with...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Błażej Rubiś

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  18. The role of miR-27b-5p in Head and Neck Squamous Cell Carcinoma.

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Joanna Kozłowska

    Wielkopolskie Centrum Onkologii im. Marii Skłodowskiej-Curie

  19. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  20. New antimycotic polycations - synthesis, chemical characterization, toxicity and antifungal spectrum

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Kamil Kamiński

    Uniwersytet Jagielloński, Wydział Chemii

  21. Analysis of miRNA in extracellular vesicles from respiratory tract associated with asthma pathomechanism in pediatric po...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Dominika Ambrożej

    Warszawski Uniwersytet Medyczny

  22. In search for molecular targets to overcome doxorubicin resistance in triple-negative breast cancer with the use of inno...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Anna Pogorzelska

    Narodowy Instytut Leków

  23. Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodege...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  24. Correlations between supramolecular structure, molecular dynamics, physico-chemical stability, and solubility in neat Ac...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Karolina Jurkiewicz

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  25. Selective activation of non-nuclear Estrogen Receptor signaling with PaPE-1 as a novel therapeutic approach for sporadic...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  26. Molecular mechanism of the protective effect of swimming training on skeletal muscle atrophy and the course of amyotroph...

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: prof. Wiesław Ziółkowski

    Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

  27. Enzymes of the L-methionine biosynthetic pathway as novel moleculartargets for antifungal chemotherapy

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Iwona Gabriel

    Politechnika Gdańska, Wydział Chemiczny

  28. The study on the molecular mechanisms of cytotoxic activity of new compounds ZOT5-1-Me and ZOT5-1-Et in an experimental ...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Paulina Tokarz

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  29. Epidemiology and rapid spread of antimicrobial resistance amongAcinetobacter spp. strains in hospital units - analysis u...

    Call: PRELUDIUM BIS 2 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Chmielarczyk

    Uniwersytet Jagielloński, Collegium Medicum

  30. Genomic profiling of circulating biomarkers and matched primary tumors from breast cancer patients

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr Aleksandra Markiewicz

    Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  31. Molecular profiling of novel antipsychotic drug candidates

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Jan Rodriguez Parkitna

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  32. Development of an in vitro model for the evaluation of phototoxicity of drugs with different affinity to melanin using a...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Jakub Rok

    Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Farmaceutycznych w Sosnowcu

  33. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Przemysław Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  34. Early Detection and surveillance of Esophageal cancer with the Cytosponge™ and Nucleic acid biomarkers (the EDEN study)...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: Władysław Januszewicz

    Centrum Medyczne Kształcenia Podyplomowego

  35. Searching for the molecular bases of mephedrone-induced biphasic response to social interactions in rats

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Olga Wronikowska

    Uniwersytet Medyczny w Lublinie, Wydział Lekarsko-Dentystyczny

  36. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the ...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr Natalia Małek-Chudzik

    Politechnika Wrocławska

  37. Assessment of exosomal circRNA expression profile in children with cystic fibrosis

    Call: PRELUDIUM 19 , Panel: NZ5

    Principal investigator: Zuzanna Stachowiak

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  38. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  39. New steroid sulfatase inhibitors based on 1,2,4-oxadiazole sulfamate derivatives

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Karol Biernacki

    Politechnika Gdańska, Wydział Chemiczny

  40. Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Kinga Gawlińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  41. Allergic inflammation in particular types of work-related asthma in the context of exposure to low and high molecular we...

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: Agnieszka Lipińska-Ojrzanowska

    Instytut Medycyny Pracy im. prof. dr. med. Jerzego Nofera

  42. Identification of molecular mechanism of Escherichia coli response to antimicrobial blue light inactivation by genome-wi...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: dr Aleksandra Rapacka-Zdończyk

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  43. Individual biological response of breast cancer tumours to proton irradiation in correlation with molecular and microenv...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Julian Malicki

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  44. Investigation of molecular mechanisms of rapid antidepressant action of NLX-101, a biased agonist of the 5-HT1A receptor...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  45. Seeking for CB1 and CB2 receptor ligands among drugs, drug metabolites, and phytochemical compounds

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Adam Stasiulewicz

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  46. The influence of EGFRvIII structure and its cellular distribution heterogeneity on designing new therapeutic and diagnos...

    Call: OPUS 18 , Panel: NZ3

    Principal investigator: prof. Piotr Rieske

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  47. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kuter

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  48. DHA/EPA and changes of peripheral blood cell epigenetics as well as the level of endothelial and pancreatic beta cell sp...

    Call: MAESTRO 1 , Panel: NZ2

    Principal investigator: prof. Aldona Dembińska-Kieć

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydzial Lekarski

  49. Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Goszczyński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  50. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Kaja Karaś

    Instytut Biologii Medycznej Polskiej Akademii Nauk

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