Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to modulate the enzymatic activity and transcription of nuclear receptors as the elements of their molecular mechanism of action.

2019/33/B/NZ7/02534

Keywords:

antitumor bisacridines UAs drug-DNA interactions ABC proteins transcriptional effect of drugs antitumor drug metabolism nuclear receptors urine and blood metabolites.

Descriptors:

  • NZ1_2: Biochemistry
  • NZ3_1: Cell biology
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Politechnika Gdańska

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Zofia Mazerska 

Number of co-investigators in the project: 10

Call: OPUS 17 - announced on 2019-03-15

Amount awarded: 3 011 720 PLN

Project start date (Y-m-d): 2020-04-02

Project end date (Y-m-d): 2023-04-01

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

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