Projects funded by the NCN
Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis of tissue-specific interaction and activation of Th17 lymphocytes.
2019/35/N/NZ7/01618
Keywords:
RORgamma ligand immunomodulation CDK inhibitor adoptive cell transfer
Descriptors:
- NZ7_15: Toxicology
- NZ7_12: Prevention of human diseases
- NZ2_6: Immunogenetics
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Instytut Biologii Medycznej Polskiej Akademii Nauk
woj.
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 18 - announced on 2019-09-16
Amount awarded: 139 920 PLN
Project start date (Y-m-d): 2020-07-02
Project end date (Y-m-d): 2024-07-01
Project duration:: 48 months (the same as in the proposal)
Project status: Project completed
Project description
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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (1)
- Anti-hepatocellular carcinoma activity of the cyclin-dependent kinase inhibitor AT7519Authors:Kaja Karaś, Iwona Karwaciak, Katarzyna Chałaśkiewicz, Anna Sałkowska, Joanna Pastwińska, Rafał A. Bachorz, Marcin RatajewskiAcademic press:Biomedicine & Pharmacotherapy (rok: 2023, tom: 164, strony: 115002), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.biopha.2023.115002 - link to the publication