Search results

51. 3D hybrid organ-on-chip (hOCP) platform for skeletal muscle tissue: a predictive in vitro model and an advanced tool for…

Principal investigator: dr Marco Costantini

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: POLONEZ 3, Panel: NZ1

52. Mitochondrial translocation of the DNA repair protein APE1

Principal investigator: dr Carlo Vascotto

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: POLONEZ 3, Panel: NZ1

53. Biomimetic hydrogel based hybrid materials for tissue engineering aiming at bone defects repair

Principal investigator: dr hab. Joanna Małgorzata Lewandowska-Łańcucka

Uniwersytet Jagielloński, Wydział Chemii

Call: SONATA 11, Panel: ST5

54. New ways of early diagnosticts of colorectar cancer using Sirt3 as mitochondrial DNA repair regulator

Principal investigator: prof. Ireneusz Jacek Majsterek

Uniwersytet Medyczny w Łodzi, Międzywydziałowa Katedra Chemii i Biochemii Medycznej

Call: OPUS 10, Panel: NZ5

55. Mechanisms of ribonucleotides incorporation and repair in E.coli cells

Principal investigator: dr Karolina Makieła-Dzbeńska

Instytut Biochemii i Biofizyki PAN

Call: HARMONIA 7, Panel: NZ3

56. DNA repair mechanisms: from coarse-grained to atomistic description

Principal investigator: dr Adam Kazimierz Sieradzan

Uniwersytet Gdański, Wydział Chemii

Call: SONATA 9, Panel: ST4

57. Super-resolution optical imaging of higher order chromatin structures in nuclei of human cells, during DNA replication a…

Principal investigator: prof. Jerzy Dobrucki

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 6, Panel: NZ3

58. The role of homologous recombination DNA repair mediators in the maintenance of centromere integrity.

Principal investigator: dr hab. Dorota Dziadkowiec

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: HARMONIA 5, Panel: NZ1

59. Novel mechanisms of tissue repair: effect of miR-378/miR-378* on blood vessel formation for ischemic muscles regeneratio…

Principal investigator: prof. Józef Dulak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 4, Panel: NZ1

60. Identification of triple negative breast cancer with inactive DNA damage repair pathway by homologous recombination base…

Principal investigator: dr Paweł Wenancjusz Domagała

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

Call: SONATA 3, Panel: NZ5

61. Studies on the new generation of scaffolds from modified nano- and microfibril collagen with embedded stem cells in aspe…

Principal investigator: dr hab. Krystyna Pietrucha

Politechnika Łódzka, Wydział Technologii Materiałowych i Wzornictwa Tekstyliów

Call: OPUS 2, Panel: ST8

62. Effect of heterozygous mutations and radiaton on expression of DNA repair genes- MRE11, RAD50 and NBN in the cells of ac…

Principal investigator: prof. Jerzy Stanisław Nowak

Instytut Genetyki Człowieka PAN

Call: OPUS 1, Panel: NZ5

63. Midkine, a multifunctional cytokine, in inflammatory bowel diseases (Crohn's disease and ulcerative colitis) - role in p…

Principal investigator: dr Małgorzata Krzystek-Korpacka

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski

Call: SONATA 1, Panel: NZ5

64. Maintaining the stability of the mitochondrial genome in cells of the model organism Saccharomyces cerevisiae: a multi-n…

Principal investigator: dr Aneta Edyta Kaniak-Golik

Instytut Biochemii i Biofizyki PAN

Call: OPUS 4, Panel: NZ3

65. Is ADP-ribosylation involved in the response to DNA double-strand breaks? An investigation employing the CRISPR-Cas9 sys…

Principal investigator: Weronika Justyna Pawluś

Uniwersytet Jagielloński

Call: PRELUDIUM 24, Panel: NZ3

66. Role of stem cell- derived extracellular vesicles in regulation of autophagy and mitochondrial homeostasis in cardiac ce…

Principal investigator: prof. Ewa Katarzyna Zuba-Surma

Uniwersytet Jagielloński

Call: OPUS 28, Panel: NZ4

67. SUMOylation control over spatiotemporal response to replication stress in eukaryotic cells

Principal investigator: dr Karol Krzysztof Kramarz

Uniwersytet Wrocławski

Call: OPUS 28, Panel: NZ2

68. NIR-active Multi-layer Coatings for Titanium Alloys to Disinfect Superbugs

Principal investigator: dr hab. Vignesh Kumaravel

Politechnika Łódzka

Call: OPUS 28 (LAP), Panel: ST11

69. Quad-TNT: Quadruplex-Targeted Photo-Therapy for Triple-Negative Tumors

Principal investigator: dr Marco Deiana

Politechnika Wrocławska

Call: SONATA BIS 14, Panel: NZ5

70. Predictive Potential of Circulating MicroRNA Biomarkers in Patients with High Familial or Genetic Risk of Cancer

Principal investigator: prof. Wojciech Fendler

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: OPUS 25, Panel: NZ5

71. Novel factors involved in cell cycle control after DNA damage.

Principal investigator: dr Michał Zbigniew Malewicz

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Call: OPUS 21, Panel: NZ1

72. The NORAD-stress granule axis and its role in the hyperthermia-induced radio-/chemosensitization of cancer cells.

Principal investigator: dr Jakub Andrzej Kochan

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: SONATA 16, Panel: NZ3

73. Assessment of the possibility of using vitamin D3 in the prevention and treatment of pulmonary fibrosis in the course of…

Principal investigator: dr hab. Marta Kinga Lemieszek

Instytut Medycyny Wsi im. Witolda Chodźki

Call: SONATA BIS 10, Panel: NZ7

74. Photodamage and self-healing of primordial forms of DNA and RNA.

Principal investigator: dr Rafał Kazimierz Szabla

Politechnika Wrocławska

Call: OPUS 19, Panel: ST4

75. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Principal investigator: prof. Tomasz Adam Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 19, Panel: NZ7

76. Mechanism of potentiating effect of low-dose fractionated radiation (LDFRT) on paclitaxel and carboplatin in head and ne…

Principal investigator: dr hab. Dorota Słonina

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

Call: PRELUDIUM BIS 1, Panel: NZ3

77. Investigating the role of Arabidopsis thaliana MutLγ endonuclease in meiotic crossover designation

Principal investigator: Nadia Kbiri

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 18, Panel: NZ2

78. Homo consumens, Homo ecologicus - ecological efficiency test of the new directive on certain aspects concerning contract…

Principal investigator: prof. Fryderyk Andrzej Zoll

Uniwersytet Jagielloński, Wydział Prawa i Administracji

Call: MAESTRO 11, Panel: HS5

79. Canonical Liability of Catholic Church Bishops for Sexual Abuse Inflicted on Minors by Clerics under Such Bishops' Respo…

Principal investigator: dr hab. Piotr Majer

Uniwersytet Papieski Jana Pawła II w Krakowie, Wydział Prawa Kanonicznego

Call: OPUS 17, Panel: HS5

80. Analysis of the functions of isoforms of plant FEN1 and their phosphorylation using Arabidopsis thaliana as an experimen…

Principal investigator: dr hab. Wojciech Kazimierz Strzałka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 17, Panel: NZ3

81. Mechanisms of enhanced cytotoxicity of phleomycin by antimony and cadmium using the yeast Saccharomyces cerevisiae as a …

Principal investigator: Ewa Zofia Pilarczyk

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: PRELUDIUM 16, Panel: NZ2

82. Identification and functional characterization of proteins interacting with cohesin complex in yeast Saccharomyces cerev…

Principal investigator: dr Ireneusz Bernard Litwin

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: OPUS 16, Panel: NZ2

83. Identification and functional characterization of long non-coding RNAs involved in the ATM-dependent response to DNA dam…

Principal investigator: dr hab. Agnieszka Dzikiewicz-Krawczyk

Instytut Genetyki Człowieka PAN

Call: OPUS 14, Panel: NZ1

84. Global and local chromatin reorganisation in cellular response to DNA double-strand breaks, investigated with super-reso…

Principal investigator: prof. Jerzy Dobrucki

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 14, Panel: NZ3

85. The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact…

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

Call: OPUS 13, Panel: NZ7

86. How activation of the Mec1/Tel1 kinase (human ATR/ATM) pathway in response to the nuclear genome damage influences the s…

Principal investigator: dr Aneta Edyta Kaniak-Golik

Instytut Biochemii i Biofizyki PAN

Call: OPUS 13, Panel: NZ3

87. The impact of anti-cancer therapies on genetic stability of chondrocytes differentiated from human pluripotent stem cell…

Principal investigator: dr Ewelina Stelcer

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

Call: PRELUDIUM 12, Panel: NZ7

88. Identification of the mechanism of sensitization of human ovarian cancer cells to anticancer drugs by the DNA double str…

Principal investigator: Anna Macieja

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: PRELUDIUM 12, Panel: NZ7

89. Resolving structure and functions of RECQL4 and BLM helicases to understand consequences of deleterious genetic alterati…

Principal investigator: prof. Bożena Kamińska-Kaczmarek

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: HARMONIA 8, Panel: NZ3

90. The application of the yeast model to investigate the genotoxic properties of antimony

Principal investigator: prof. Robert Wysocki

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: OPUS 11, Panel: NZ2

91. Unraveling the molecular basis of DNA damage recognition and processing in human mitochondria

Principal investigator: dr Michal Roman Szymanski

Uniwersytet Rzeszowski, Wydział Medyczny

Call: POLONEZ 2, Panel: NZ1

92. Investigating the ubiquitylation network of Irc20 and Tfb3 ubiquitin ligases needed upon DNA damage

Principal investigator: dr Ewa Katarzyna Błaszczak

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: SONATA 11, Panel: NZ1

93. RecA independent response of tubercle bacilli to DNA damage

Principal investigator: dr hab. Anna Brzostek

Instytut Biologii Medycznej PAN

Call: OPUS 10, Panel: NZ6

94. Genotoxicity of antitumor compound 3-bromopyruvate in the yeast Saccharomyces cerevisiae.

Principal investigator: dr Magdalena Cal

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: SONATA 9, Panel: NZ2

95. Protection of hematopoietic stem cells from premature aging - classical and non-classical role of heme oxygenase 1.

Principal investigator: dr Krzysztof Tomasz Szade

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 6, Panel: NZ3

96. The role of DNA translocase Irc5 in DNA damage response in Saccharomyces cerevisiae

Principal investigator: dr Ireneusz Bernard Litwin

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: SONATA 6, Panel: NZ2

97. Characterizing the functions of plant PCNA1 and PCNA2 proteins using Arabidopsis thaliana as an experimental model

Principal investigator: dr Wojciech Kazimierz Strzałka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: SONATA BIS 3, Panel: NZ1

98. Quantitative analysis of spontaneous single-strand DNA breaks and ensuing replication stress in human cells.

Principal investigator: Magdalena Maria Kordon

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 5, Panel: NZ3

99. Genetic background of aminoglycoside-induced hearing loss - mitochondrial and nuclear genes involvement

Principal investigator: dr Małgorzata Aleksandra Rydzanicz

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: SONATA 5, Panel: NZ5

100. Cellular and molecular mechanisms of the adult neurogenesis dysfunctions in cyclin D2-deficient mice

Principal investigator: dr Artur Czupryn

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Call: OPUS 4, Panel: NZ4

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