Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Studies on the new generation of scaffolds from modified nano- and microfibril collagen with embedded stem cells in aspect of repairing central nervous system

2011/03/B/ST8/05867

Keywords:

collagen scaffolds electrospinning stem cells CNS

Descriptors:

  • ST8_8: Mechanics of solids
  • NZ1_8: Tissue engineering

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Politechnika Łódzka, Wydział Technologii Materiałowych i Wzornictwa Tekstyliów

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Krystyna Pietrucha 

Number of co-investigators in the project: 9

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 899 500 PLN

Project start date (Y-m-d): 2012-08-29

Project end date (Y-m-d): 2016-04-28

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zamrażarka niskotemperaturowa (20 000 PLN)
  2. Liofilizator LABCONCO wraz z wyposażeniem i pompą próżniową (80 000 PLN)

Information in the final report

  • Publication in academic press/journals (13)
  • Articles in post-conference publications (7)
  1. Building up and characterization of multi-component collagen-based scaffolds
    Authors:
    K. Pietrucha
    Academic press:
    IFMBE Proceedings (rok: 2014, tom: 41, strony: 1626-1629), Wydawca: Springer International Publishing Switzerland, L.M. Roa Romero (ed.)
    Status:
    Published
    DOI:
    10.1007/978-3-319-00846-2_401 - link to the publication
  2. Neuronal and glial progenitors obtained from human iPS cells on 3D modified collagen scaffolds-the tool for the neurodevelopmental and neurotoxicity studies
    Authors:
    Zychowicz M., Pietrucha K., Podobinska M., Augustyniak J., Winiarska H., Buzanska L.
    Academic press:
    Folia Neuropathologica (rok: 2014, tom: 52, strony: 371-372), Wydawca: Official Journal of Mossakowski Medical Research Centre Polish Academy of Sciences and Polish Association of Neuropathologists
    Status:
    Published
  3. Physicochemical properties of 3D collagen-CS scaffolds for potential use in neural tissue engineering
    Authors:
    Krystyna Pietrucha
    Academic press:
    International Journal of Biological Macromolecules (rok: 2015, tom: 80, strony: 732-739), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijbiomac.2015.07.005 - link to the publication
  4. A new method of determination of collagen conjugated with keratin
    Authors:
    M. Safandowska, K. Pietrucha,
    Academic press:
    AUTEX Research Journal (rok: 2013, tom: 13, strony: 37-39), Wydawca: AUTEX Association of Universities for Textiles
    Status:
    Published
    DOI:
    10.2478/V10304-012-0024-6 - link to the publication
  5. Collagenous scaffolds supplemented with hyaluronic acid and chondroitin sulfate used for wound fibroblast and embryonic nerve cell culture
    Authors:
    Jacek Drobnik, Krystyna Pietrucha, Lucyna Piera, Jacek Szymanski, Alicja Szczepanowska
    Academic press:
    Advances in Clinical and Experimental Medicine (rok: 2017, tom: 26, strony: 223-230), Wydawca: Wroclaw Medical University
    Status:
    Published
    DOI:
    10.17219/acem/62835 - link to the publication
  6. Development of collagen cross-linked with dialdehyde cellulose as a potential 3D scaffold for neural tissue engineering
    Authors:
    Krystyna Pietrucha
    Academic press:
    IFMBE Proceedings (rok: 2015, tom: 45, strony: 349-352), Wydawca: Springer International Publishing Switzerland
    Status:
    Published
    DOI:
    10.1007/978-3-319-11128-5_87 - link to the publication
  7. Functional properties of different collagen scaffolds to create a biomimetic niche for neurally committed human induced pluripotent stem cells (iPSC)
    Authors:
    Krystyna Pietrucha, Marzena Zychowicz, Martyna Podobinska, Leonora Buzanska
    Academic press:
    Folia Neuropathologica (rok: 2017, tom: 55, strony: 110-123), Wydawca: Official Journal of Mossakowski Medical Research Centre Polish Academy of Sciences and Polish Association of Neuropathologists
    Status:
    Published
  8. Pore structure and dielectric behaviour of the 3D collagen-DAC scaffolds designed for nerve tissue repair
    Authors:
    Krystyna Pietrucha, Ewa Marzec, Marcin Kudzin
    Academic press:
    International Journal of Biological Macromolecules (rok: 2016, tom: 92, strony: 1298-1306), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijbiomac.2016.08.029 - link to the publication
  9. Processes of gamma radiolysis of soluble collagen in the aspect of the scaffolds preparation
    Authors:
    K. Pietrucha
    Academic press:
    IFMBE Proceedings (rok: 2014, tom: 41, strony: 1622-1625), Wydawca: Springer International Publishing Switzerland, L.M. Roa Romero (ed.)
    Status:
    Published
    DOI:
    10.1007/978-3-319-00846-2_400 - link to the publication
  10. The behavior of embrionic neural cells within the 3D micro-structured collagen-based scaffolds
    Authors:
    Krystyna Pietrucha, Jacek Szymański, Jacek Drobnik
    Academic press:
    IFMBE Proceedings (rok: 2015, tom: 45, strony: 549-552), Wydawca: Springer International Publishing Switzerland, I. Lackovic and D. Vasic (eds.)
    Status:
    Published
    DOI:
    10.1007/978-3-319-11128-5_137 - link to the publication
  11. Comparison of various types of collagenous scaffolds applied for embryonic nerve cell culture
    Authors:
    J. Drobnik, K. Pietrucha, M. Kudzin, K. Mader, J. Szymański, A. Szczepanowska
    Academic press:
    Biologicals (rok: 2017, tom: 46, strony: 74-80), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biologicals.2017.01.001 - link to the publication
  12. Dialdehyde cellulose-crosslinked collagen and its physicochemical properties
    Authors:
    Krystyna Pietrucha, Marta Safandowska
    Academic press:
    Process Biochemistry (rok: 2015, tom: 50, strony: 2105-2111), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.procbio.2015.09.025 - link to the publication
  13. Effect of fish collagen modification on its thermal and rheological properties
    Authors:
    M. Safandowska, K. Pietrucha
    Academic press:
    International Journal of Biological Macromolecules (rok: 2013, tom: 53, strony: 32-37), Wydawca: Elsevier
    Status:
    Published
  1. Dielectric behaviour and morphology of collagen-based scaffolds designed to create hybrid system with stem cells
    Authors:
    K. Pietrucha
    Conference:
    2016 Engii Conferences January Series, Materials &Mathematic Conference (rok: 2016, ), Wydawca: Scientific Research Publishing, Bangkok, Thailand
    Data:
    konferencja January 14-16
    Status:
    Published
  2. Processes of gamma radiolysis of collagen in aspect of the scaffolds preparation
    Authors:
    K. Pietrucha
    Conference:
    XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013 (rok: 2013, ), Wydawca: Laura M. Roa Romero (Ed), Springer
    Data:
    konferencja 47021
    Status:
    Published
  3. Building up characterization of multicomponent collagen-based scaffolds
    Authors:
    K. Pietrucha
    Conference:
    XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013 (rok: 2013, ), Wydawca: Laura M. Roa Romero, Springer
    Data:
    konferencja September 25-28,
    Status:
    Published
  4. Hybrid Scaffolds Of Collagen Modified by Dialdehyde Cellulose with iPS-derived of Neural Precursor Cells
    Authors:
    K. Pietrucha, M. Zychowicz, J. Augustyniak, M. Podobinska, L. Buzanska
    Conference:
    27th Europan Conference on Biomaterials (rok: 2015, ), Wydawca: Polish Society for Biomaterials, Kraków 2015, Poland
    Data:
    konferencja 30th August-3rd September
    Status:
    Published
  5. Some collagen scaffolds in neural tissue engineering
    Authors:
    J. Drobnik, K. Pietrucha
    Conference:
    1-st Matrix Biology Europe (MBE) Conference (rok: 2014, ), Wydawca: NVMB Dutch Society for Matrix Biology
    Data:
    konferencja 21-24 June
    Status:
    Published
  6. The role of oxygen tension in the developmental stage dependent response of HUCB+NSC to MeHgCl treatment
    Authors:
    J. Augustyniak, M. Zychowicz, K. Pietrucha, H. Winiarska, L. Buzanska
    Conference:
    The 18-th International Congress on In Vitro Toxicology ESTIV2014 (rok: 2014, ), Wydawca: Egmond aa Zee, The Netherlands
    Data:
    konferencja June 10-13
    Status:
    Published
  7. Incorporation of the Chondroitin Sulphate Scaffolds to Create a Biomimetic Niche with Neurally Committed Human Induced Pluripotent Stem Cells
    Authors:
    K. Pietrucha, M. Zychowicz, J. Augustynial, M. Podoninska, L. Buzanska
    Conference:
    27th European Conference on Biomaterials (rok: 2015, ), Wydawca: Polish Society for Biomaterials, Kraków 2015, Poland
    Data:
    konferencja 30th August - 3rd September
    Status:
    Published