Projects funded by the NCN
How activation of the Mec1/Tel1 kinase (human ATR/ATM) pathway in response to the nuclear genome damage influences the stability of mitochindrial genome: a study on the yeast model of mutations in polymerase POLG.
2017/25/B/NZ3/01811
Keywords:
mitochondrial genome DNA repair mutagenesis ATM kinase ATR kinase mitochondrion
Descriptors:
- NZ1_10:
- NZ1_1:
- NZ3_1:
Panel:
NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution :
Instytut Biochemii i Biofizyki Polskiej Akademii Nauk
woj. mazowieckie
Principal investigator (from the host institution):
Number of co-investigators in the project: 4
Call: OPUS 13 - announced on 2017-03-15
Amount awarded: 818 000 PLN
Project start date (Y-m-d): 2018-01-09
Project end date (Y-m-d): 2023-01-08
Project duration:: 60 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (3)
- Developmental delay with hypotrophy associated with homozygous functionally relevant REV3L variantAuthors:Halas A, Fijak-Moskal J, Kuberska R, Murcia Pienkowski V, Kaniak-Golik A, Pollak A, Poznanski J, Rydzanicz M, Bik-Multanowski M, Sledziewska-Gojska E, Płoski R.Academic press:Journal of Molecular Medicine (rok: 2021, tom: 99(3), strony: 415-423), Wydawca: Berlin : Springer InternationalStatus:PublishedDOI:10.1007/s00109-020-02033-3 - link to the publication
- PCNA and Rnh1 independently participate in the protection of mitochondrial genome against UV-induced mutagenesis in yeast cellsAuthors:Martyna Latoszek, Katarzyna Baginska-Drabiuk, Ewa Sledziewska-Gojska, Aneta Kaniak-GolikAcademic press:Scientific Reports (rok: 2024, tom: 14, strony: 31017), Wydawca: Nature PortfolioStatus:PublishedDOI:10.1038/s41598-024-82104-4 - link to the publication
- The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi ApparatusAuthors:Damian Kolakowski, Weronika Rzepnikowska, Aneta Kaniak-Golik, Teresa Zoladek, Joanna KaminskaAcademic press:International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 12274), Wydawca: Basel, Switzerland : MDPIStatus:PublishedDOI:10.3390/ijms222212274 - link to the publication