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Mechanisms of ribonucleotides incorporation and repair in E.coli cells

2015/18/M/NZ3/00402

Keywords:

DNA replication

Descriptors:

  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Karolina Makieła-Dzbeńska 

Number of co-investigators in the project: 3

Call: HARMONIA 7 - announced on 2015-06-15

Amount awarded: 549 360 PLN

Project start date (Y-m-d): 2016-04-12

Project end date (Y-m-d): 2021-04-11

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Obecność rybonukleotydów w DNA ma antagonistyczne znaczenie dla utrzymania stabilności genetycznej organizmów
    Authors:
    Łazowski K, Makiela-Dzbenska K.
    Academic press:
    Postępy Biochemii (rok: 2019, tom: 65(2), strony: 143-152), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    10.18388/pb.2019_247 - link to the publication
  2. Role of RNase H enzymes in maintaining genome stability in Escherichia coli expressing a steric-gate mutant of pol VICE391.
    Authors:
    WALSH E., HENRIKUS S.S., VAISMAN A., MAKIEŁA-DZBEŃSKA K., ARMSTRONG T. J., ŁAZOWSKI K., MCDONALD J.P., GOODMAN M.F., van OIJEN A.M., JONCZYK P., FIJAŁKOWSKA I.J., ROBINSON A.R., WOODGATE R.
    Academic press:
    DNA Repair (rok: 2019, tom: 84, strony: 45306), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dnarep.2019.102685 - link to the publication
  3. Novel Escherichia coli active site dnaE alleles with altered base and sugar selectivity
    Authors:
    Vaisman Alexandra, Walsh Erin, Łazowski Krystian, Reijns Martin, McDonald John, Moreno Kristiniana, Quiros Dominic, Schmidt Marlen, Kranz Harald, Yang Wei, Makiela-Dzbenska Karolina, Woodgate Roger
    Academic press:
    Molecular Microbiology (rok: 2021, tom: 116, strony: 909-925), Wydawca: Wiley-Blackwell
    Status:
    Published
    DOI:
    brak - link to the publication
  4. Replication fidelity in E. coli: Differential leading and lagging strand effects for dnaE antimutator alleles.
    Authors:
    MAKIEŁA-DZBEŃSKA K., MASŁOWSKA K.H., KUBAŃ W., GAWEŁ D., JONCZYK P., SCHAAPER R.M, FIJAŁKOWSKA I.J.
    Academic press:
    DNA Repair (rok: 2019, tom: 83, strony: 45298), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dnarep.2019.102643 - link to the publication
  5. The SOS system: a complex and tightly regulated response to DNA damage.
    Authors:
    MASŁOWSKA K.H., MAKIEŁA-DZBEŃSKA K., FIJAŁKOWSKA I.J.
    Academic press:
    Environmental and Molecular Mutagenesis (rok: 2019, tom: 60, strony: 368-384), Wydawca: Wiley Periodicals, Inc. on behalf of Environmental Mu tagen Society
    Status:
    Published
    DOI:
    10.1002/em.22267 - link to the publication

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