Mechanisms of ribonucleotides incorporation and repair in E.coli cells

2015/18/M/NZ3/00402

Keywords

DNA replication

Descriptors

NZ3_1: Biologia komórki

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Instytut Biochemii i Biofizyki PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Karolina Makieła-Dzbeńska

Number of co-investigators in the project: 3

Call

HARMONIA 7 – announced on 2015-06-15

Amount awarded: 549 360 PLN
Project start date: 2016-04-12
Project end date: 2021-04-11
Project duration: 60 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

Replication fidelity in E. coli: Differential leading and lagging strand effects for dnaE antimutator alleles.

Authors:
MAKIEŁA-DZBEŃSKA K., MASŁOWSKA K.H., KUBAŃ W., GAWEŁ D., JONCZYK P., SCHAAPER R.M, FIJAŁKOWSKA I.J.

Academic press:
DNA Repair (year: 2019, volume: 83, pages: 46029), Publisher: Elsevier

Status:
Published

DOI:
10.1016/j.dnarep.2019.102643 – link to the publication
Role of RNase H enzymes in maintaining genome stability in Escherichia coli expressing a steric-gate mutant of pol VICE391.

Authors:
WALSH E., HENRIKUS S.S., VAISMAN A., MAKIEŁA-DZBEŃSKA K., ARMSTRONG T. J., ŁAZOWSKI K., MCDONALD J.P., GOODMAN M.F., van OIJEN A.M., JONCZYK P., FIJAŁKOWSKA I.J., ROBINSON A.R., WOODGATE R.

Academic press:
DNA Repair (year: 2019, volume: 84, pages: 46037), Publisher: Elsevier

Status:
Published

DOI:
10.1016/j.dnarep.2019.102685 – link to the publication
Novel Escherichia coli active site dnaE alleles with altered base and sugar selectivity

Authors:
Vaisman Alexandra, Walsh Erin, Łazowski Krystian, Reijns Martin, McDonald John, Moreno Kristiniana, Quiros Dominic, Schmidt Marlen, Kranz Harald, Yang Wei, Makiela-Dzbenska Karolina, Woodgate Roger

Academic press:
Molecular Microbiology (year: 2021, volume: 116, pages: 909-925), Publisher: Wiley-Blackwell

Status:
Published
The SOS system: a complex and tightly regulated response to DNA damage.

Authors:
MASŁOWSKA K.H., MAKIEŁA-DZBEŃSKA K., FIJAŁKOWSKA I.J.

Academic press:
Environmental and Molecular Mutagenesis (year: 2019, volume: 60, pages: 368-384), Publisher: Wiley Periodicals, Inc. on behalf of Environmental Mu tagen Society

Status:
Published

DOI:
10.1002/em.22267 – link to the publication
Obecność rybonukleotydów w DNA ma antagonistyczne znaczenie dla utrzymania stabilności genetycznej organizmów

Authors:
Łazowski K, Makiela-Dzbenska K.

Academic press:
Postępy Biochemii (year: 2019, volume: 65(2), pages: 143-152), Publisher: Polskie Towarzystwo Biochemiczne

Status:
Published

DOI:
10.18388/pb.2019_247 – link to the publication

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