Projects funded by the NCN

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156 projects found matching your search criteria :

  1. The molecular basis of stress-induced anxiety and affective disorders

    Call: OPUS 2 , Panel: NZ2

    Principal investigator: dr Michał Korostyński

    Instytut Farmakologii PAN

  2. Dioscuri Center for Structural Dynamics of Receptors

    Call: DIOSCURI 4 , Panel: NZ1

    Principal investigator: Przemysław Nogły

    Uniwersytet Jagielloński

  3. Antibacterial molecules based on bacteriophage proteins and constant antibody fragments with therapeutic potential for t...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Karolina Aleksandra Filik-Matyjaszczyk

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  4. Application of bioconjugation strategy to the synthesis of anticancer Trojan horses

    Call: OPUS 28 , Panel: ST5

    Principal investigator: dr hab. Michał Piotr Antoszczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  5. 2-in-1: Octafluoroazobenzenes as ON/OFF photoswitches and anion-binding sites in macrocyclic lithium halides receptors

    Call: PRELUDIUM 23 , Panel: ST5

    Principal investigator: Jakub Narodowiec

    Instytut Chemii Organicznej Polska Akademia Nauk

  6. Cellular effects in the tumor microenvironment and the potential for targeted delivery of molecules associated with the ...

    Call: OPUS 27 , Panel: NZ4

    Principal investigator: prof. Magdalena Maria Staniszewska

    Katolicki Uniwersytet Lubelski Jana Pawła II

  7. Macro-to-Micro: Fabrication of synthetic receptor based microsensors for certain protein sensing

    Call: OPUS 27 , Panel: ST11

    Principal investigator: dr hab. Piyush Sindhu Sharma

    Instytut Chemii Fizycznej Polskiej Akademii Nauk

  8. Targeting Proteinopathies: Understanding and Mitigating the Effects of Pathogenic Mutations in Cullin-RING Ubiquitin Lig...

    Call: OPUS 27 , Panel: NZ3

    Principal investigator: dr hab. Wojciech Mieczysław Pokrzywa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  9. Molecular mechanisms underlying the liver injury induced by ulipristal acetate treatment

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Aleksandra Natalia Łupińska

    Instytut Rozrodu Zwierząt i Badań Żywności PAN

  10. Zn2+-dependent competition between CD4 and CD8α coreceprtor for Lck tyrosine kinase

    Call: SONATA 19 , Panel: NZ1

    Principal investigator: dr Anna Marta Kocyła

    Uniwersytet Wrocławski, Wydział Biotechnologii

  11. Deciphering the importance of the intracellular FGFR1 module for cell fate

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  12. Retro-inverso modification of zinc(II)–GLP-1 receptor agonist complexes – from bioinorganic chemistry to animal studies...

    Call: OPUS 26 , Panel: ST5

    Principal investigator: dr hab. Magdalena Alina Rowińska-Żyrek

    Uniwersytet Wrocławski, Wydział Chemii

  13. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński, Collegium Medicum

  14. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Danuta Dudzik

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  15. Proteolytic processing of adhesion G-protein coupled receptors through proteases

    Call: WEAVE-UNISONO , Panel: NZ1

    Principal investigator: dr Renata Katarzyna Mężyk-Kopeć

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  16. Study on novel sensing layers for determination of quorum sensing signal molecules

    Call: SONATA BIS 13 , Panel: ST5

    Principal investigator: dr hab. Kamila Sadowska

    Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza PAN

  17. Crownphyrins - hybrids of crown ethers and porphyrins, constituting macrocyclic platforms for the construction of two- a...

    Call: PRELUDIUM BIS 5 , Panel: ST4

    Principal investigator: dr hab. Bartosz Jakub Szyszko

    Uniwersytet Wrocławski, Wydział Chemii

  18. Novel receptor materials for the construction of a bioelectronic nose for the rapid and efficient detection of lung canc...

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  19. Molecular geometry – pre- and post-synthetically modified shape-persistent macrocycles of great chiroptical response, fo...

    Call: OPUS 25 , Panel: ST5

    Principal investigator: prof. Marcin Grzegorz Kwit

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  20. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr...

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii PAN

  21. Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Sławomir Hubert Filipek

    Uniwersytet Warszawski, Wydział Chemii

  22. Psychedelic-induced molecular changes in the brain

    Call: SONATINA 7 , Panel: NZ2

    Principal investigator: dr Dominik Łukasz Cysewski

    Uniwersytet Medyczny w Białymstoku

  23. Function, organization, dynamics, and evolution of hyperbranched receptor-binding protein systems in Klebsiella jumbo ph...

    Call: OPUS 24 (LAP) , Panel: NZ1

    Principal investigator: prof. Zuzanna Drulis-Kawa

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  24. In vitro and in vivo investigations of the radiometals influence on the ability of CCK2R receptors imaging by the radiol...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Renata Radosława Mikołajczak

    Narodowe Centrum Badań Jądrowych

  25. Molecular implications of gut microbiota disorders in the context of the immune system functioning in patients with prim...

    Call: OPUS 23 , Panel: NZ6

    Principal investigator: prof. Ewelina Pia Grywalska

    Uniwersytet Medyczny w Lublinie

  26. Proinsulin C-peptide and G protein-coupled receptor 146 (GPR146) – clinical investigation of the impact of their signall...

    Call: PRELUDIUM 21 , Panel: NZ4

    Principal investigator: Aleksandra Ryk

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  27. Highly-internalizing intrinsically fluorescent oligomeric cytotoxic conjugate targeting breast cancer cells overproducin...

    Call: PRELUDIUM 21 , Panel: NZ1

    Principal investigator: dr Natalia Porębska

    Uniwersytet Wrocławski, Wydział Biotechnologii

  28. Use of comparative oncology approach to dissect the PD-1 intrinsic signalling in osteosarcoma. Can dog be the key for ne...

    Call: PRELUDIUM 21 , Panel: NZ1

    Principal investigator: Katarzyna Joanna Dziubek

    Uniwersytet Gdański, Międzynarodowe Centrum Badań nad Szczepionkami Przeciwnowotworowymi

  29. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Magdalena Białoń

    Instytut Farmakologii PAN

  30. Peptide receptor complexes for auxin canalization and regeneration in Arabidopsis.

    Call: OPUS 22 (LAP) , Panel: NZ1

    Principal investigator: dr Ewa Mazur

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  31. Synthesis and applications of sumanene derivatives as innovative, selective and effective molecular receptors of caesium...

    Call: OPUS 22 , Panel: ST4

    Principal investigator: dr Artur Kasprzak

    Politechnika Warszawska, Wydział Chemiczny

  32. Brain GABAB receptors as determinants of obesity phenotypes: evaluation of adolescent female and male rats

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  33. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  34. FGFR2-->JunB axis in progression of ER+ breast cancer - molecular analyses and prognostication

    Call: PRELUDIUM BIS 3 , Panel: NZ3

    Principal investigator: dr hab. Rafał Sebastian Sądej

    Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  35. Molecular mechanisms of 5-HT7R-mediated resilience in stress-related disorders

    Call: OPUS 21 , Panel: NZ4

    Principal investigator: prof. Jakub Mateusz Włodarczyk

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  36. Design of metal-peptide complexes based on amyloid β sequence with a His-2 binding motif as selective receptors in elect...

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Aleksandra Magdalena Tobolska

    Politechnika Warszawska

  37. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  38. Cooperative and collective phenomena in cell membrane adhesion

    Call: SHENG 2 , Panel: NZ1

    Principal investigator: dr hab. Bartosz Jan Różycki

    Instytut Fizyki PAN

  39. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Paweł Aleksander Siedlecki

    Instytut Biochemii i Biofizyki PAN

  40. Self-learning systems in the design of compounds modulating GPCR receptors activation.

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Dorota Latek

    Uniwersytet Warszawski, Wydział Chemii

  41. Parallel quantitative evaluation of targetability, cellular uptake, and intracellular drug release for the establishment...

    Call: OPUS 20 (LAP) , Panel: ST5

    Principal investigator: prof. Adolfo Rivero Müller

    Uniwersytet Medyczny w Lublinie, Wydział Nauk Medycznych

  42. Identification and characterisation of novel anti-bacterial restriction factors

    Call: Polskie Powroty NAWA 2020 , Panel: NZ1

    Principal investigator: dr Michał Piotr Wandel

    Instytut Biochemii i Biofizyki PAN

  43. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Mikołaj Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  44. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: dr Przemysław Patryk Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  45. Molecular mechanism underlying the anti-inflammatory action of CB2 receptor agonists in microglia: participation of the ...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: dr Natalia Eleonora Małek-Chudzik

    Politechnika Wrocławska

  46. FAST interactions in cell death regulation

    Call: PRELUDIUM 19 , Panel: NZ1

    Principal investigator: Daria Martyna Dawidziak

    Uniwersytet Warszawski, Wydział Chemii

  47. Making use of siderophore transport systems to deliver peptide nucleic acids to bacterial cells

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  48. Determination of the mechanisms responsible for the mobility of non-integrin laminin receptor (LamR) isoforms, including...

    Call: PRELUDIUM 19 , Panel: NZ1

    Principal investigator: Ewa Mazurkiewicz

    Uniwersytet Wrocławski, Wydział Biotechnologii

  49. Role of the Intersubunit and Interdomain Interactions in the GABAA Receptor Modulation by Protons.

    Call: ETIUDA 8 , Panel: NZ1

    Principal investigator: Michał Adam Michałowski

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  50. Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor ...

    Call: SONATINA 4 , Panel: NZ1

    Principal investigator: dr Aleksandra Anna Twarda-Cłapa

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

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