Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The Molecular Function of Alpha-Dystrobrevin-1 at the Postsynaptic Machinery of the Neuromuscular Junction

2013/09/B/NZ3/03524

Keywords:

neuromuscular junction dystrobrevin dystroglycan complex acetylcholine receptors AChR

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ3_6: Cell neurobiology
  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Tomasz Prószyński 

Number of co-investigators in the project: 6

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 893 400 PLN

Project start date (Y-m-d): 2014-03-03

Project end date (Y-m-d): 2017-03-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Komputer - stacja graficzna (10 000 PLN)
  2. System oświetlenia fluorescencyjnego do mikroskopu (29 000 PLN)
  3. Oświetlacz UV z systemem (aparatem) do robienia zdjęć (15 000 PLN)
  4. Inkubator z wytrząsaniem do hodowli bakterii (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (7)
  1. Dystrobrevin recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction
    Authors:
    Jacinthe Gingras, Marta Gawor, Krzysztof M. Bernadzki, R. Mark Grady, Peter Hallock, David J. Glass, Joshua R. Sanes, Tomasz J. Proszynski
    Academic press:
    JOURNAL OF CELL SCIENCE (rok: 2016, tom: 129, strony: 898-911), Wydawca: The Company of Biologists Ltd
    Status:
    Published
    DOI:
    10.1242/jcs.181180 - link to the publication
  2. Liprin-α-1 is a novel component of the murine neuromuscular junction and is involved in the organization of the postsynaptic machinery
    Authors:
    Krzysztof M. Bernadzki, Marta Gawor, Marcin Pęziński, Paula Mazurek, Paweł Niewiadomski, Jolanta Rędowicz, and Tomasz J. Prószyński
    Academic press:
    Scientific Reports (rok: 2017, tom: 7, strony: 45303), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-017-09590-7 - link to the publication
  3. Podosomes in muscle cells and their role in the remodeling of neuromuscular postsynaptic machinery
    Authors:
    Bernadzki KM, Rojek KO, Prószyński TJ.
    Academic press:
    European Journal of Cell Biology (rok: 2014, tom: 93, strony: 478-4485), Wydawca: Elsever
    Status:
    Published
    DOI:
    10.1016/j.ejcb.2014.06.002 - link to the publication
  1. Novel alpha-Dystrobrevin interactors regulate neuromuscular junction postsynaptic machinery
    Authors:
    Marta Gawor, Jacinthe Gingras, Krzysztof Bernadzki, R., Paweł Niewiadomski, Mark Grady, Peter Hallock, David J. Glass, Joshua R. Sanes and Tomasz J. Prószy
    Conference:
    12th International Congress of PNS (rok: 2015, ), Wydawca: Acta Neurobiologiae Axperimentalis
    Data:
    konferencja 6-8 wrzesień 2015
    Status:
    Published
    DOI:
    link to the publication
  2. Spatial distribution of neuromuscular junction components. Pretzels are more complex than we have anticipated
    Authors:
    Marta Gawor, Paweł Niewiadomski, Krzysztof Bernadzki, Tomasz Prószyński
    Conference:
    FENS 2016 (rok: 2016, ), Wydawca: FENS
    Data:
    konferencja 2-6 lipca 2016
    Status:
    Published
    DOI:
    link to the publication
  3. Liprin-α-1 is a novel component of the neuromuscular junction and involved in the organization of the postysynaptic machinery
    Authors:
    Krzysztof M. Bernadzki, Marta Gawor, Marcin Pęziński, Paula Mazurek, Paweł Niewiadomski, Jolanta Rędowicz, and Tomasz J. Prószyński
    Conference:
    PTBUN 2017 (rok: 2017, ), Wydawca: PTBUN
    Data:
    konferencja 28-31 sierpnia 2017
    Status:
    Published
    DOI:
    link to the publication
  4. More Than A Pretzel: Spatial Distribution Of The Neuromuscular Junction Components
    Authors:
    Marta Gawor, PhD, Paweł Niewiadomski, PhD, Patrycja Daszczuk, MSc, Krzysztof Bernadzki, MSc, Tomasz J. Prószyński, PhD
    Conference:
    Conference Name: 13th International Conference on Myasthenia Gravis and Related Disorders (rok: 2017, ), Wydawca: New York Academy of Sciences
    Data:
    konferencja 12-17 maja 2017
    Status:
    Published
  5. Spatial distribution of neuromuscular junction components. Pretzels are more complex than we have anticipated
    Authors:
    Prószyński T.J.,
    Conference:
    Molecular and Cell Biology of the Neuromuscular System (rok: 2016, ), Wydawca: University of Basel
    Data:
    konferencja 18-23 października 2016
    Status:
    Published
  6. Spatial distribution of neuromuscular junction components. Pretzels are more complex than we have anticipated
    Authors:
    Tomasz Prószyński
    Conference:
    2016 Spring Padua Muscle Days (rok: 2016, ), Wydawca: European Journal of Translational Myology
    Data:
    konferencja 13-16 kwietnia 2016
    Status:
    Published
  7. Jak powstają precle? Badania nad molekularną maszynerią sterującą rozwojem synaps.
    Authors:
    Tomasz J. Prószyński, Paweł Niewiadomski
    Conference:
    Symbioza (rok: 2015, ), Wydawca: Uniwersytet Warszawski
    Data:
    konferencja 29-30 maja
    Status:
    Published
    DOI:
    link to the publication

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