Projects funded by the NCN
The molecular mechanism of Hecate-FSHbeta conjugate action on tumor cells expressing follicle stimulating hormone receptor (FSHR)
2012/05/B/NZ5/01867
Keywords:
FSH FSHR Hecate cancer ovary testis prostate
Descriptors:
- NZ5_7: Human disease treatment
- NZ5_3: Pathogenesis of human diseases
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Instytut Rozrodu Zwierząt i Badań Żywności PAN
woj. warmińsko-mazurskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 8
Call: OPUS 3 - announced on 2012-03-15
Amount awarded: 760 500 PLN
Project start date (Y-m-d): 2013-03-06
Project end date (Y-m-d): 2016-03-05
Project duration:: 36 months (the same as in the proposal)
Project status: Project settled
Information in the final report
- Publication in academic press/journals (3)
- Transgenic mice expressing inhibin a-subunit promoter (inha)/Simian Virus 40 T-antigen (Tag) transgene as a model for the therapy of granulosa cell-derived ovarian cancerAuthors:Marcin Chrusciel, Milena Doroszko, Joanna Stelmaszewska, Xiangdong Li, Adam J. Ziecik, Herjan J.T. Coelingh-Bennink, Ilpo Huhtaniemi, Nafis A. RahmanAcademic press:Reproductive Biology (rok: 2014, tom: 14, strony: 25-31), Wydawca: ElsevierStatus:PublishedDOI:10.1016/j.repbio.2013.11.005. - link to the publication
- Revisiting the expression and function of follicle-stimulation hormone receptor in human umbilical vein endothelial cells.Authors:Stelmaszewska, Joanna; Chruściel, Marcin; Doroszko, Milena; Akerfelt, Malin; Ponikwicka-Tyszko, Donata; Nees, Matthias; Frentsch, Marco; Li, Xiangdong; Kero, Jukka; Huhtaniemi, Ilpo; Wołczyński, Sławomir; Rahman, Nafis A.Academic press:Scientific Reports (rok: 2016, tom: 16(6):37095, strony: 45303), Wydawca: Nature ResearchStatus:PublishedDOI:10.1038/srep37095 - link to the publication
- Functional expression of FSH receptor in endometriotic lesions.Authors:Ponikwicka-Tyszko, Donata; Chruściel, Marcin; Stelmaszewska, Joanna; Bernaczyk, Piotr; Sztachelska, Maria; Sidorkiewicz, Iwona; Doroszko, Milena; Tomaszewski, Jakub; Tapanainen, Juha S.; Huhtaniemi, Ilpo; Wołczyński, Sławomir; Rahman, NafisAcademic press:Journal of Clinical Endocrinology & Metabolism (rok: 2016, tom: 101(7), strony: 2905-2914), Wydawca: Oxford AcademicStatus:PublishedDOI:10.1210/jc.2016-1014 - link to the publication