Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Searching for the molecular mechanisms of the therapeutic use of histamine signal and histamine receptors H1R, H2R and H4R in the inflammatory bowel disease.

2012/04/M/NZ6/00355

Keywords:

inflammatory bowel disease histamine receptors T helper and regulatory lymphocytes

Descriptors:

  • NZ6_2: Clinical immunology
  • NZ5_7: Human disease treatment
  • NZ5_5: Diagnostics in human diseases

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Lekarski

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marek Jutel 

Number of co-investigators in the project: 7

Call: HARMONIA 2 - announced on 2011-12-15

Amount awarded: 809 900 PLN

Project start date (Y-m-d): 2012-10-08

Project end date (Y-m-d): 2016-03-07

Project duration:: 41 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (8)
  1. Biology of the microbiome: interactions with the host immune response
    Authors:
    Sylwia Smolinska, David Groeger, Liam O'Mahony
    Academic press:
    Gastroenterology Clinics of North America (rok: 2017, tom: vol. 45 no. 1, strony: 19-35), Wydawca: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.gtc.2016.09.004 - link to the publication
  2. Histamine-secreting microbes are increased in the gut of adult asthma patients
    Authors:
    Weronika Barcik, Benoit Pugin, Patrick Westermann, Noelia Rodriguez Perez, Ruth Ferstl, Sylwia Smolinska, Marek Jutel, Edith Hessel, David Michalowich, Cezmi A. Akdis, Remo Frei, Liam O'Mahony
    Academic press:
    The Journal of Allergy and Clinical Immunology (rok: 2016, tom: vol. 138 no. 5, strony: 1491-1494, 1494.el-1494.e7), Wydawca: Elsevier Inc.
    Status:
    Published
    DOI:
    10.1016/j.jaci.2016.05.049 - link to the publication
  3. Altered Fatty Acid Metabolism and Reduced Stearoyl-Coenzyme A Desaturase Activity in Asthma
    Authors:
    N. Rodriguez-Perez, E. Schiavi, R. Frei, R. Ferstl, P. Wawrzyniak, S. Smolinska, M. Sokolowska, N. Sevi, M. Kohler, D. Michalovich, K. Simpson, E.M. Hessel, M. Jutel, M.M. Martin-Fontecha, O. Palomares, C.A. Akdis, L. O'Mahony
    Academic press:
    Allergy (rok: 2017, tom: -, strony: -), Wydawca: Published by John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/all.13180 - link to the publication
  4. Intestinal Dendritic Cells
    Authors:
    Schiavi E., Smolinska S., O'Mahony L.
    Academic press:
    Current Opinion in Gastroenterology (rok: 2015, tom: vol. 31 no. 2, strony: 98-103), Wydawca: Wolters Kluwer Health, Inc.
    Status:
    Published
    DOI:
    10.1097/MOG.0000000000000155. - link to the publication
  5. Exposure to non-microbial N-Glycolylneuraminic acid confers protection against allergic airway-inflammation
    Authors:
    Remo Frei, Ruth Ferstl, Caroline Roduit, Mario Ziegler, Elisa Schiavi, Weronika Barcik, Noelia Rodriguez-Perez, Oliver F. Wirz, Marcin Wawrzyniak, Benoit Pugin, Dirk Nehrbass, Marek Jutel, Sylwia Smolinska, Patrycja Konieczna, Christian Bieli, Susanne Loeliger, Marco Waser, Göran Pershagen, Josef Riedler, Martin Depner, Bianca Schaub, Jon Genuneit, Harald Renz, Juha Pekkanen, Anne M. Karvonen, Jean-Charles Dalphin, Marianne van Hage, Gert Doekes, Mübeccel Akdis, Charlotte Braun-Fahrländer, Cezmi A. Akdis, Erika von Mutius, Liam O'Mahony, Roger P. Lauener, and the teams of the PARSIFAL21 and PASTURE/EFRAIM22 study
    Academic press:
    Journal of Allergy and Clinical Immunology (rok: 2017, ), Wydawca: Elsevier Inc.
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  6. Histamine and gut mucosal immune regulation
    Authors:
    S. Smolinska, M. Jutel, R. Crameri, L. O'Mahony
    Academic press:
    Allergy: European Journal of Allergy & Clinical Immunology (rok: 2014, tom: vol. 69 no. 3, strony: 273–281), Wydawca: Published by John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/all.12330 - link to the publication
  7. Allergen Immunotherapy: past, present and future
    Authors:
    Jutel M., Kosowska A., Smolinska S.
    Academic press:
    Allergy, Asthma & Immunology Research (rok: 2016, tom: vol. 8 no. 3, strony: 191-197), Wydawca: Korean Academy of Asthma, Allergy and Clinical Immunology; Korean Academy of Pediatric Allergy and Respiratory Disease
    Status:
    Published
    DOI:
    10.4168/aair.2016.8.3.191. - link to the publication
  8. Histamine Receptor 2 is Required to Suppress Innate Immune Responses to Bacterial Ligands in Patients with Inflammatory Bowel Disease
    Authors:
    Sylwia Smolinska, David Groeger, Noelia Rodriguez Perez, Elisa Schiavi, Ruth Ferstl, Remo Frei, Patrycja Konieczna, Cezmi A. Akdis, Marek Jutel, Liam O'Mahony
    Academic press:
    Inflammatory Bowel Diseases (rok: 2016, tom: vol. 22 no. 7, strony: 1575-1586), Wydawca: Wolters Kluwer Health, Inc.
    Status:
    Published
    DOI:
    10.1097/MIB.0000000000000825 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy