Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Search results

254 projects found matching your search criteria :

  1. Study of ligand binding and activation processes of formyl, opioid and cannabinoid G-protein-coupled receptors

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Sławomir Hubert Filipek

    Uniwersytet Warszawski, Wydział Chemii

  2. Psychedelic-induced molecular changes in the brain

    Call: SONATINA 7 , Panel: NZ2

    Principal investigator: dr Dominik Łukasz Cysewski

    Uniwersytet Medyczny w Białymstoku

  3. Development of novel anti-cancer immunotherapy against mesothelioma comprising of oncolytic adenovirus vectors armed wit...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Łukasz Kuryk

    Narodowy Instytut Zdrowia Publicznego PZH - Państwowy Instytut Badawczy

  4. Palladium-catalyzed cascades for the rapid and enantioselective construction of polycyclic scaffolds of alkaloids and ps...

    Call: OPUS 24 , Panel: ST4

    Principal investigator: dr hab. Rafał Antoni Loska

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  5. Effect of lignans on biomass and toxigenic profile of Fusarium graminearum.

    Call: OPUS 2 , Panel: NZ9

    Principal investigator: dr hab. Tomasz Kulik

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Kształtowania Środowiska i Rolnictwa

  6. Thermodynamic contribution of halogen bonds in protein-ligand systems. Design, synthesis, and thermodynamic studies of m...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: dr Sławomir Jan Kasperowicz

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  7. Metallocarbaporphyrinoids as ligands in monomeric and oligomeric complexes. Synthesis, interactions, and catalysis.

    Call: OPUS 23 , Panel: ST4

    Principal investigator: prof. Piotr Jan Chmielewski

    Uniwersytet Wrocławski, Wydział Chemii

  8. The role of simultaneous and individual modulation of μ-opioid, sigma-1 and histamine H3 receptors as a new therapeutic ...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  9. Crystallographic analysis of RNA-ligand complexes. Towards rational design oflead compounds for development of therapies...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Ludmiła Kiliszek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  10. Allosteric and allosteric-orthosteric bitopic ligands of histamine receptor H4 as a way to increase selectivity and bias...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sławomir Hubert Filipek

    Uniwersytet Warszawski, Wydział Chemii

  11. Metallosupramolecular architectures based on flexidentate pyridyl-β-diketonate ligands - synthesis, properties and catal...

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Gracjan Piotr Kurpik

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  12. Novel tricyclic glycomimetics as DC-SIGN receptor ligands.

    Call: OPUS 22 , Panel: ST4

    Principal investigator: dr Mykhaylo Potopnyk

    Instytut Chemii Organicznej Polskiej Akademii Nauk

  13. Development of the knowledge on the role of GPR18 ligands as a microglia-targeted strategy in the regulation of neuroinf...

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Ewelina Barbara Honkisz-Orzechowska

    Uniwersytet Jagielloński, Collegium Medicum

  14. Targeting cell surface proteoglycans with high affinity multimeric ligands and their cytotoxic conjugates – towards prec...

    Call: OPUS 22 , Panel: NZ1

    Principal investigator: dr hab. Łukasz Opaliński

    Uniwersytet Wrocławski, Wydział Biotechnologii

  15. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Katarzyna Justyna Kieć-Kononowicz

    Uniwersytet Jagielloński, Collegium Medicum

  16. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: prof. Kinga Aleksandra Sałat

    Uniwersytet Jagielloński, Collegium Medicum

  17. Reversible modulation of G-quadruplex functions using photoresponsive ligands - in vitro and cellular studies

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Marta Maria Dudek

    Politechnika Wrocławska

  18. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

    Uniwersytet Jagielloński, Collegium Medicum

  19. True Bioisosteres - Structural and Thermodynamic Classification of Molecular Fragments for Ligand Design

    Call: SONATA BIS 11 , Panel: ST4

    Principal investigator: dr Maura Dagmara Malińska

    Uniwersytet Warszawski, Wydział Chemii

  20. Deciphering the molecular mechanism of activity switch of the ubiquitin ligase CHIP

    Call: PRELUDIUM 20 , Panel: NZ1

    Principal investigator: Pankaj Thapa

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  21. Combating addiction by targeting α3β4*-nicotinic acetylcholine receptors

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Ákos Nemecz

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

  22. Impact of hydrological regimes on the quantitive and qualitative optical properties of dissolved organic matter in West ...

    Call: OPUS 21 , Panel: ST10

    Principal investigator: dr Monika Dorota Zabłocka

    Instytut Oceanologii Polskiej Akademii Nauk

  23. Survey of Chinese Communist Party provincial-level committees: a quantitative approach

    Call: PRELUDIUM 20 , Panel: HS5

    Principal investigator: Adrian Krystian Brona

    Uniwersytet Jagielloński, Wydział Studiów Międzynarodowych i Politycznych

  24. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  25. Living on the edge: evolutionary adaptation of substrate-recruiting subunits of the cullin-RING ubiquitin ligase complex...

    Call: PRELUDIUM 20 , Panel: NZ1

    Principal investigator: Natalia Anna Szulc

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  26. First-in-class dual biased agonists of serotonin 5-HT1A and dopamine D2 receptors – an innovative approach in the search...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Marcin Roman Kołaczkowski

    Uniwersytet Jagielloński, Collegium Medicum

  27. The interactome of Upf1 (Nam7) ubiquitin ligase - deciphering thesubstrates and novel biological functions

    Call: PRELUDIUM 20 , Panel: NZ2

    Principal investigator: Natalia Joanna Łazarewicz

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  28. Wood from pine family (Pinaceae) native to Poland as a potent source of pharmacologically active lignans

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Andrzej Patyra

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  29. Advanced coordination materials designed on the basis of functional silsesquioxanes

    Call: OPUS 21 , Panel: ST5

    Principal investigator: dr hab. Beata Dudziec

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum Zaawansowanych Technologii

  30. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Paweł Aleksander Siedlecki

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  31. AXL receptor signaling in cancer cell growth and drug resistance

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: prof. Marta Elżbieta Miączyńska

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  32. Photodynamics of metal complexes with 2,6-bis(thiazol-2-yl)pyridine derivatives functionalized by aryls and N-donors as ...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Anna Maria Maroń

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  33. Multifunctional character of copper(II) macrocyclic complexes – utilization in atom transfer radical polymerization (ATR...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Adam Paweł Gorczyński

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  34. The new methodology for better understanding of ligand-RNA interactions.

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr Filip Artur Stefaniak

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej w Warszawie

  35. Silsesquioxanes as Multifunctional Ligands in Coordination Chemistry and Nano-Building Blocks for Hybrid Materials

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Łukasz John

    Uniwersytet Wrocławski, Wydział Chemii

  36. New therapies of opioid use disorder

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr Wojciech Barnaba Solecki

    Uniwersytet Jagielloński, Wydział Zarządzania i Komunikacji Społecznej

  37. Anti-cancer strategy based on the induced G-quadruplex formation. Structural and biological properties of ligand-RNA/mRN...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Dorota Gudanis-Sobocińska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  38. Input of the structure of influenza A virus RNA on regulation of virus proliferation. High throughput screening of small...

    Call: OPUS 20 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  39. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Mikołaj Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  40. New 5-HT6 receptor ligands from the group of sulfonamide derivatives of cyclic arylguanidines in the treatment of gliobl...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: dr Przemysław Patryk Zaręba

    Politechnika Krakowska im. Tadeusza Kościuszki, Wydział Inżynierii i Technologii Chemicznej

  41. Investigation into the mechanism of regulation of nicotinic acetylcholine receptors

    Call: POLS , Panel: NZ3

    Principal investigator: dr Ákos Nemecz

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Nauk Biologicznych i Weterynaryjnych

  42. New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Anna Marta Pasieka

    Uniwersytet Jagielloński, Collegium Medicum

  43. Novel approach in the search for asthma and COPD therapies - computer aided design of multi-target-directed ligands bloc...

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Alicja Aleksandra Gawalska

    Uniwersytet Jagielloński, Collegium Medicum

  44. Interconversions of supramolecular architectures based on Schiff base ligands and transition metal ions as potential pro...

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Martyna Szymańska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  45. Structure-function relationship in fibroblast growth factor signaling

    Call: CEUS-UNISONO , Panel: NZ3

    Principal investigator: dr hab. Małgorzata Urszula Zakrzewska

    Uniwersytet Wrocławski

  46. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Andrzej Mikołaj Pilc

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  47. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: Katarzyna Anna Szczepańska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  48. Role of the Intersubunit and Interdomain Interactions in the GABAA Receptor Modulation by Protons.

    Call: ETIUDA 8 , Panel: NZ1

    Principal investigator: Michał Adam Michałowski

    Uniwersytet Wrocławski, Wydział Nauk Biologicznych

  49. Chasing the HARE: elucidation of the binding mechanism of the new and unexplored ligandsof the Hyaluronic Acid Receptor ...

    Call: SONATINA 4 , Panel: NZ1

    Principal investigator: dr Aleksandra Anna Twarda-Cłapa

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  50. Do potential new MRGPRX2 ligands induce mastocytes degranulation in human?

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: dr hab. Grzegorz Porębski

    Uniwersytet Jagielloński, Collegium Medicum