Projects funded by the NCN
Functional selectivity of novel histamine H4 receptor ligands
2016/23/N/NZ7/01906
Keywords:
biased ligands histamine H4 receptor functional selectivity beta-arrestin-2
Descriptors:
- NZ7_14: Pharmacy, pharmacotherapy, pharmacology
Panel:
NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution :
Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 12 - announced on 2016-09-15
Amount awarded: 99 940 PLN
Project start date (Y-m-d): 2017-10-12
Project end date (Y-m-d): 2021-10-11
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Pipeta elektroniczna wielokanałowa (5 500 PLN)
Information in the final report
- Publication in academic press/journals (1)
- Articles in post-conference publications (4)
- Trisubstituted 1,3,5-Triazines as Histamine H4 Receptor Antagonists with Promising Activity In VivoAuthors:Agnieszka Olejarz-Maciej, Szczepan Mogilski, Tadeusz Karcz, Tobias Werner, Katarzyna Kamińska, Jarosław Kupczyk, Ewelina Honkisz-Orzechowska, Gniewomir Latacz, Holger Stark, Katarzyna Kieć-Kononowicz and Dorota ŁażewskaAcademic press:Molecules (rok: 2023, tom: 28, strony: 4199), Wydawca: MDPIStatus:PublishedDOI:10.3390/molecules28104199 - link to the publication
- Biased activity of novel aryl-1,3,5-triazine derivatives (w "Book of Abstracts").Authors:Agnieszka Olejarz-Maciej, Katarzyna Kamińska, Małgorzata Więcek, Dorota Łażewska, Tadeusz Karcz, Timo Litmann, Armin Buschauer, Katarzyna Kieć-KononowiczConference:VIII Meeting of the Paul Ehrlich Euro-PhD Network (rok: 2018, ), Wydawca: nie dotyczyData:konferencja 12-14.07.2018Status:Published
- Searching for biased histamine H4R ligands in the group of novel aryl-1,3,5-triazine derivatives. (Poster abstract 23 w "Program Abstracts List of Participants")Authors:Agnieszka Olejarz-Maciej, Katarzyna Kamińska, Małgorzata Więcek, Dorota Łażewska, Tadeusz Karcz, Timo Litmann, Armin Buschauer, Katarzyna Kieć-KononowiczConference:9th Summer School Medicinal Chemistry (rok: 2018, ), Wydawca: nie dotyczyData:konferencja 19-21.09.2018Status:Published
- The European Histamine Research Society 48th Annual Meeting, May 15–18th, 2019 Kraków, Poland; Tekst opublikowany w: Inflammation Research 68, 1–49 (2019). https://doi.org/10.1007/s00011-019-01266-4 (Tytuł streszczenia: B-ARRESTIN RECRUITMENT BY HISTAMINE H4 RECEPTOR LIGANDS FROM THE GROUP OF NOVEL ARYL-1,3,5-TRIAZINE DERIVATIVES na stronie 39)Authors:Agnieszka Olejarz-Maciej, Katarzyna Kamińska, Małgorzata Więcek, Dorota Łażewska, Tadeusz Karcz, Timo Littmann, Armin Buschauer, Katarzyna Kieć-KononowiczConference:The European Histamine Research Society 48th Annual Meeting (rok: 2019, ), Wydawca: Springer NatureData:konferencja 2019-05-15 do 2019-05-18Status:Published
- β-arrestin recruitment by histamine H4R ligands from the group of analogues of JNJ7777120Authors:Agnieszka Olejarz-Maciej, Małgorzata Więcek, Maria Kaleta, Tadeusz Karcz, Jadwiga Handzlik, Katarzyna Kieć-KononowiczConference:X Konwersatorium Chemii Medycznej (rok: 2021, ), Wydawca: nie dotyczyData:konferencja 3-5 września 2021Status:Published