Functional selectivity of novel histamine H4 receptor ligands
2016/23/N/NZ7/01906
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny
Voivodeship: małopolskie
Principal investigator (from the host institution)
Agnieszka Urszula Olejarz-Maciej
Number of co-investigators in the project: 2
Call
PRELUDIUM 12 – announced on 2016-09-15
- Amount awarded
- 99 940 PLN
- Project start date
- 2017-10-12
- Project end date
- 2021-10-11
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Pipeta elektroniczna wielokanałowa. Cost: 5 500 PLN
Information in the final report
Publication in academic press/journals (1)
-
Trisubstituted 1,3,5-Triazines as Histamine H4 Receptor Antagonists with Promising Activity In Vivo
- Authors:
- Agnieszka Olejarz-Maciej, Szczepan Mogilski, Tadeusz Karcz, Tobias Werner, Katarzyna Kamińska, Jarosław Kupczyk, Ewelina Honkisz-Orzechowska, Gniewomir Latacz, Holger Stark, Katarzyna Kieć-Kononowicz and Dorota Łażewska
- Academic press:
- Molecules (year: 2023, volume: 28, pages: 4199), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/molecules28104199 – link to the publication
Articles in post-conference publications (4)
-
β-arrestin recruitment by histamine H4R ligands from the group of analogues of JNJ7777120
- Authors:
- Agnieszka Olejarz-Maciej, Małgorzata Więcek, Maria Kaleta, Tadeusz Karcz, Jadwiga Handzlik, Katarzyna Kieć-Kononowicz
- Conference:
- X Konwersatorium Chemii Medycznej (year: 2021, pages: 98), Publisher: nie dotyczy
- Date:
- conference 3-5 września 2021
- Status:
- Published
-
Biased activity of novel aryl-1,3,5-triazine derivatives (w Book of Abstracts).
- Authors:
- Agnieszka Olejarz-Maciej, Katarzyna Kamińska, Małgorzata Więcek, Dorota Łażewska, Tadeusz Karcz, Timo Litmann, Armin Buschauer, Katarzyna Kieć-Kononowicz
- Conference:
- VIII Meeting of the Paul Ehrlich Euro-PhD Network (year: 2018, pages: 57), Publisher: nie dotyczy
- Date:
- conference 12-14.07.2018
- Status:
- Published
-
Searching for biased histamine H4R ligands in the group of novel aryl-1,3,5-triazine derivatives. (Poster abstract 23 w Program Abstracts List of Participants)
- Authors:
- Agnieszka Olejarz-Maciej, Katarzyna Kamińska, Małgorzata Więcek, Dorota Łażewska, Tadeusz Karcz, Timo Litmann, Armin Buschauer, Katarzyna Kieć-Kononowicz
- Conference:
- 9th Summer School Medicinal Chemistry (year: 2018, pages: 49), Publisher: nie dotyczy
- Date:
- conference 19-21.09.2018
- Status:
- Published
-
The European Histamine Research Society 48th Annual Meeting, May 15–18th, 2019 Kraków, Poland; Tekst opublikowany w: Inflammation Research 68, 1–49 (2019). https://doi.org/10.1007/s00011-019-01266-4 (Tytuł streszczenia: B-ARRESTIN RECRUITMENT BY HISTAMINE H4 RECEPTOR LIGANDS FROM THE GROUP OF NOVEL ARYL-1,3,5-TRIAZINE DERIVATIVES na stronie 39)
- Authors:
- Agnieszka Olejarz-Maciej, Katarzyna Kamińska, Małgorzata Więcek, Dorota Łażewska, Tadeusz Karcz, Timo Littmann, Armin Buschauer, Katarzyna Kieć-Kononowicz
- Conference:
- The European Histamine Research Society 48th Annual Meeting (year: 2019, pages: 39), Publisher: Springer Nature
- Date:
- conference 2019-05-15 do 2019-05-18
- Status:
- Published