Projects funded by the NCN

Discovery and development of small-molecule inhibitors of USP2 for targeted, non-genotoxic therapy of cancer

Call: OPUS 1 , Panel: ST5

Principal investigator: prof. Tadeusz Andrzej Holak

Uniwersytet Jagielloński, Wydział Chemii

Selective inhibition of NMDAR activity during epileptogenesis as a therapeutic approach to cure epilepsy

Call: SONATA 10 , Panel: NZ7

Principal investigator: dr Adam Gorlewicz

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

The influence of emotion on perceptual processing, response inhibition and error monitoring. An event-related potential ...

Call: OPUS 10 , Panel: HS6

Principal investigator: dr hab. Magdalena Senderecka

Uniwersytet Jagielloński, Wydział Filozoficzny

Design, synthesis and biological evaluation of the new steroid sulfatase (STS) inhibitors based on sulfamate analogs con...

Call: PRELUDIUM 10 , Panel: NZ7

Principal investigator: Mateusz Daśko

Politechnika Gdańska, Wydział Chemiczny

New hydrids of tetrahydroacridine derivatives as a acetylocholinesterase with multifunctional activity

Call: OPUS 10 , Panel: NZ7

Principal investigator: prof. Paweł Bartosz Szymański

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

In vivo and in vitro structure of influenza virus RNA. The structural determinants behind the inhibition of influenza vi...

Call: OPUS 10 , Panel: NZ1

Principal investigator: prof. Elżbieta Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

The role of cognitive inhibition in the involuntary mental time travel.A comprehensive investigation of involuntary auto...

Call: SONATA 10 , Panel: HS6

Principal investigator: dr Krystian Barzykowski

Uniwersytet Jagielloński, Wydział Filozoficzny

Modification of cellular aging in vitro by inhibitors of non-enzymatic protein modifications

Call: OPUS 9 , Panel: NZ3

Principal investigator: prof. Grzegorz Bartosz

Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

Using X-ray crystallography for localization of the sites of binding of allosteric inhibitors and activators within the ...

Call: PRELUDIUM 9 , Panel: NZ1

Principal investigator: Julia Witkowska

Uniwersytet Gdański, Wydział Chemii

Impact of the engineered mono-dispersed Fe3O4@SiO2 nanoparticles on a fungal enzyme inhibition in vitro

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: Ahmet Kertmen

Politechnika Gdańska, Wydział Chemiczny

Quantitative model for predicting CYP inhibition parameters for novel arylpiperazine derivatives.

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: dr Szymon Ulenberg

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

Investigation of the antitumor potential of stimulator of interferon genes (STING) - an adaptor protein in innate immune...

Call: PRELUDIUM 9 , Panel: NZ6

Principal investigator: Olga Sokołowska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Synthesis of new glutamate receptors antagonists and extensive investigation of their effect on tumor cells in the prese...

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Maria Wanda Bretner

Politechnika Warszawska, Wydział Chemiczny

New MOF compounds as degradable nanocontainers of tyrosine kinases inhibitors in novel anti-cancer therapy

Call: OPUS 9 , Panel: ST5

Principal investigator: prof. Artur Piotr Terzyk

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

The use of microRNA inhibitors for restoration of the expression of tumor suppressor, gene SLC5A8, and establishing of t...

Call: PRELUDIUM 9 , Panel: NZ2

Principal investigator: Wojciech Gierlikowski

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Targeting histone deacetylases as an approach to treat neonatal asphyxia.

Call: PRELUDIUM 9 , Panel: NZ7

Principal investigator: Joanna Jaworska

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

The role of DNA methylation in enhancing the sensitivity of colorectal cancer cells to topoisomerase inhibitors.

Call: PRELUDIUM 9 , Panel: NZ3

Principal investigator: Alicja Patrycja Pawlak

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Insight into biochemistry, structure, evolution and biology of bacterial serpins on example of miropin from human pathog...

Call: OPUS 9 , Panel: NZ1

Principal investigator: dr Mirosław Książek

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

New approach in bisubstrate analogs inhibitors designing.

Call: PRELUDIUM 9 , Panel: NZ1

Principal investigator: dr Maria Izabella Winiewska-Szajewska

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Protein and gene expression analysis in the course of renal cancer stem-like cells' primary resistance to sorafenib in h...

Call: PRELUDIUM 9 , Panel: NZ5

Principal investigator: Zofia Felicja Bielecka

Wojskowy Instytut Medyczny

Chemo-genetic investigation of the role of inhibitory interneurons containing somatostatin in cerebral cortex plasticity

Call: OPUS 9 , Panel: NZ4

Principal investigator: prof. Małgorzata Maria Kossut

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Covalent inhibiors of bacterial ureases - design, activity and mode of binding

Call: PRELUDIUM 9 , Panel: NZ1

Principal investigator: dr Katarzyna Magdalena Macegoniuk

Politechnika Wrocławska, Wydział Chemiczny