Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Modification of cellular aging in vitro by inhibitors of non-enzymatic protein modifications

2015/17/B/NZ3/03731

Keywords:

glycation glycation inhibitors aging fibroblasts

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ3_4: Ageing
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Grzegorz Bartosz 

Number of co-investigators in the project: 7

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 636 600 PLN

Project start date (Y-m-d): 2016-01-18

Project end date (Y-m-d): 2022-07-17

Project duration:: 78 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Aspirator.
  2. pH-metr.
  3. Zamrażarka niskotemperaturowa (45 000 PLN)
  4. Zestaw pipet.

Information in the final report

  • Publication in academic press/journals (6)
  1. Dosing metric in cellular experiments: The mol/cell metric has its limitations.
    Authors:
    Bartosz G, Pieńkowska N, Sadowska-Bartosz I.
    Academic press:
    Toxicology in vitro (rok: 2022, tom: 78, strony: 105272), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tiv.2021.105272 - link to the publication
  2. Effect of Selected Antioxidants on the In Vitro Aging of Human Fibroblasts
    Authors:
    Grzegorz Bartosz , Natalia Pieńkowska,Izabela Sadowska-Bartosz
    Academic press:
    International Journal of Molecular Sciences (rok: 2024, tom: 25, strony: 1529), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms25031529 - link to the publication
  3. Fluorescent Products of Anthocyanidin and Anthocyanin Oxidation
    Authors:
    Bartosz G, Grzesik-Pietrasiewicz M, Sadowska-Bartosz I.
    Academic press:
    J Agric Food Chem. (rok: 2020, tom: 68, strony: 12019-12027), Wydawca: ACS Publications
    Status:
    Published
    DOI:
    10.1021/acs.jafc.0c04755 - link to the publication
  4. Effect of antioxidants on the H2O2-induced premature senescence of human fibroblasts.
    Authors:
    Pieńkowska N, Bartosz G, Pichla M, Grzesik-Pietrasiewicz M, Gruchala M, Sadowska-Bartosz I.
    Academic press:
    Aging (Albany NY) (rok: 2020, tom: 12(2), strony: 1910-1927), Wydawca: Aging (Albany NY)
    Status:
    Published
    DOI:
    10.18632/aging.102730. - link to the publication
  5. Effect of Antioxidants on the Fibroblast Replicative Lifespan In Vitro.
    Authors:
    Sadowska-Bartosz I, Bartosz G.
    Academic press:
    Oxid Med Cell Longev. (rok: 2020, tom: 2020, strony: 6423783), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2020/6423783 - link to the publication
  6. Origin and pathophysiology of protein carbonylation, nitration and chlorination in age-related brain diseases and aging
    Authors:
    Gonos ES, Kapetanou M, Sereikaite J, Bartosz G, Naparło K, Grzesik M, Sadowska-Bartosz I.
    Academic press:
    Aging (Albany NY) (rok: 2018, tom: 10(5), strony: 868-901), Wydawca: Aging
    Status:
    Published
    DOI:
    10.18632/aging.101450 - link to the publication

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