Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Investigation of the antitumor potential of stimulator of interferon genes (STING) - an adaptor protein in innate immune signaling

2015/17/N/NZ6/04260

Keywords:

STING antitumor therapy proteasome inhibitor

Descriptors:

  • NZ6_1: Adaptive and innate immunity
  • NZ5_7: Human disease treatment

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Olga Sokołowska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 97 800 PLN

Project start date (Y-m-d): 2016-02-17

Project end date (Y-m-d): 2018-02-16

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  1. Immune checkpoint inhibition improves antimyeloma activity of bortezomib and STING agonist combination in Vk*MYC preclinical model
    Authors:
    Olga Sokolowska, Anna Rodziewicz-Lurzynska, Zofia Pilch, Hanna Kedzierska, Justyna Chlebowska-Tuz, Anna Sosnowska, Anna Szumera-Cieckiewicz, Kamil Sokol, Joanna Barankiewicz, Aleksander Salomon-Perzynski, Olga Ciepiela, Ewa Lech-Maranda, Jakub Golab, Dominika Nowis
    Academic press:
    Clinical and Experimental Medicine , Wydawca: Springer Nature
    Status:
    Accepted for publication
  2. STING Signaling in Cancer Cells: Important or Not?
    Authors:
    Olga Sokołowska, Dominika Nowis
    Academic press:
    Archivum Immunologiae et Therapiae Experimentalis (rok: 2018, tom: 66, strony: 125-132), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00005-017-0481-7 - link to the publication