Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Chemo-genetic investigation of the role of inhibitory interneurons containing somatostatin in cerebral cortex plasticity

2015/17/B/NZ4/02016

Keywords:

interneurons neuroplasticity learning barrel cortex inhibition chemogenetics

Descriptors:

  • NZ3_6: Cell neurobiology
  • NZ4_9: Systems neurobiology
  • NZ4_10: Neuroimaging and computational neuroscience

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Małgorzata Kossut 

Number of co-investigators in the project: 6

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 1 311 560 PLN

Project start date (Y-m-d): 2016-03-16

Project end date (Y-m-d): 2020-08-15

Project duration:: 53 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Monitor Dell.
  2. Autoklaw Extender Plus.
  3. Nanoinjektor (25 000 PLN)
  4. Wysokoobrotowa wiertarka stereotaktyczna.
  5. Stymulator wibryss (24 000 PLN)
  6. komputer z monitorem (2 szt.) (10 000 PLN)
  7. Fluovac, ekstraktor środka anestetycznego z powietrza.
  8. Ph-metr/jonometr stołowy Seven Compact.
  9. System do monitorowania stanu zwierzęcia (80 000 PLN)
  10. generator tlenu (6 000 PLN)
  11. oscyloskop (13 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Somatostatin receptors (SSTR1-5) on inhibitory interneurons in the barrel cortex
    Authors:
    Lukomska Agnieszka, Dobrzanski Grzegorz, Liguz-Lecznar Monika, Kossut Malgorzata
    Academic press:
    Brain Structure and Function (rok: 2019, tom: 2259(1), strony: 387-401), Wydawca: Springer Science + Busienss Media
    Status:
    Published
    DOI:
    10.1007/s00429-019-02011-7 - link to the publication
  2. Somatostatin receptors in the brain
    Authors:
    Łukomska Agnieszka,Dobrzański Grzegorz,Liguz -Lęcznar Monika,Kossut Małgorzata
    Academic press:
    Postępy Biochemii (rok: 2018, tom: 64(2-3), strony: 213-221), Wydawca: Polskie Towarzystwo Biochemiczne
    Status:
    Published
    DOI:
    Brak - link to the publication
  3. Application of the DREADD technique in biomedical brain research.
    Authors:
    Dobrzanski G, Kossut M.
    Academic press:
    Pharmacological Reports (rok: 2017, tom: 69(2), strony: 213-221), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.015. - link to the publication
  4. Learning-induced plasticity in the barrel cortex is disrupted by inhibition of layer 4 somatostatin-containing interneurons *
    Authors:
    Dobrzanski G1, Lukomska A1, Zakrzewska R1, Posluszny A1, Kanigowski D2, Urban-Ciecko J2, Liguz-Lecznar M1, Kossut M1*
    Academic press:
    BBA Molecular Cell Research (rok: 2021, tom: 1869(1), strony: 119146), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2021.119146 - link to the publication
  5. Somatostatin and Somatostatin-Containing Neurons in Shaping Neuronal Activity and Plasticity.
    Authors:
    Liguz-Lęcznar M.,Urban-Ciecko J., Kossut M.
    Academic press:
    Frontiers in Neurol Circuits (rok: 2016, tom: 10, strony: 48), Wydawca: Frontiers media SA
    Status:
    Published
    DOI:
    10.3389/fncir.2016.00048. - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy