Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Tick-borne encephalitis virus - search for mechanisms useful in treatment and prophylaxis.

2015/19/D/NZ6/01717

Keywords:

tick-borne encephalitis glycoprotein glycosylation inhibitors antivirals co-infection

Descriptors:

  • NZ6_5: Virology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewelina Król 

Number of co-investigators in the project: 4

Call: SONATA 10 - announced on 2015-09-15

Amount awarded: 563 650 PLN

Project start date (Y-m-d): 2016-07-22

Project end date (Y-m-d): 2021-01-21

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. System dokumentacji żeli ChemiDoc (109 500 PLN)
  2. Waga analityczna.
  3. Wirówka laboratoryjna z chłodzeniem.
  4. Spektrofluorymetr (8 500 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Anti-Tick-Borne Encephalitis Virus Activity of Novel Uridine Glycoconjugates Containing Amide or/and 1,2,3-Triazole Moiety in the Linker Structure
    Authors:
    Gabriela Brzuska, Gabriela Pastuch-Gawolek, Monika Krawczyk, Boguslaw Szewczyk, Ewelina Krol
    Academic press:
    Pharmaceuticals (rok: 2020, tom: 13(12), strony: 460), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ph13120460 - link to the publication
  2. Antiviral Activity of Uridine Derivatives of 2-Deoxy Sugars against Tick-Borne Encephalitis Virus.
    Authors:
    Krol E., Wandzik I., Brzuska G., Eyer L., Růžek D., Szewczyk B.
    Academic press:
    Molecules (rok: 2019, tom: 24, strony: 1129), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules24061129 - link to the publication
  3. The role of IFITM proteins in tick-borne encephalitis virus infection.
    Authors:
    Chmielewska AM., Gómez-Herranz M., Gach P., Nekulova M., Tyrakowska M., Lipińska AD., Rychłowski M., Hoffmann W., Król E., Vojtesek B., Sloan RD., Bieńkowska-Szewczyk K., Hupp T., Ball K.
    Academic press:
    Journal of Virology (rok: 2021, tom: brak danych, strony: brak danych), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/JVI.01130-21 - link to the publication
  4. Production and Biomedical Application of Flavivirus-like Particles.
    Authors:
    Krol E., Brzuska G., Szewczyk B.
    Academic press:
    Trends in Biotechnology (rok: 2019, tom: 37(11), strony: 1202-1216), Wydawca: Science Direct
    Status:
    Published
    DOI:
    10.1016/j.tibtech.2019.03.013 - link to the publication

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