Projects funded by the NCN

Inhibition of melanoma metastasis afrer proton beam treatment

Call: OPUS 4 , Panel: NZ4

Principal investigator: prof. Krystyna A. Urbańska

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Theoretical model of SH2-dependent STAT1 dimerization as a novel tool to identify specific compounds of functional inhib...

Call: PRELUDIUM 4 , Panel: NZ2

Principal investigator: Małgorzata Szeląg

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Kinases of emerging relevance in cancer - structural characterization.

Call: SONATA BIS 2 , Panel: NZ1

Principal investigator: dr Grzegorz Dubin

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Protein tyrosine phosphatases inhibition as a strategy against infectious diseases and bioterrorism

Call: PRELUDIUM 4 , Panel: NZ1

Principal investigator: dr Alicja Kuban-Jankowska

Gdański Uniwersytet Medyczny, Wydział Lekarski

Synthesis and pharmacological properties of mono- di- and triheterocyclic azole derivatives as a hybrid receptor and PDE...

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Maciej Henryk Pawłowski

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Cognitive Inhibition in Defense Mechanisms.

Call: PRELUDIUM 4 , Panel: HS6

Principal investigator: Marta Barbara Mrozowicz

Uniwersytet Jagielloński, Wydział Filozoficzny

DNA double-stranded break repair proteins as a target for personalized cancer therapy based on synthetic lethality

Call: OPUS 4 , Panel: NZ7

Principal investigator: dr hab. Tomasz Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

The role of dominant controlling functions over stimulation in cognitive performance in anxiety and depression.

Call: SONATA BIS 2 , Panel: HS6

Principal investigator: dr hab. Małgorzata Fajkowska

Instytut Psychologii Polskiej Akademii Nauk

Search of novel multifunctional ligands targeting neurodegereneration processes.

Call: OPUS 4 , Panel: NZ7

Principal investigator: prof. Barbara Antonina Malawska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

New chemical and biological properties of topoizomeraze I inhibitors alkylating DNA oligomers

Call: OPUS 4 , Panel: ST4

Principal investigator: prof. Lech Jan Kozerski

Instytut Chemii Organicznej Polskiej Akademii Nauk

Synthesis and analysis of potential furin inhibitors in the development of the new therapeutic strategies against viral ...

Call: PRELUDIUM 4 , Panel: ST5

Principal investigator: Monika Aleksandra Lewandowska-Goch

Uniwersytet Gdański, Wydział Chemii

In vitro/in vivo characteristics of hydrophilic matrix containing phosphodiesterase-5 inhibitors.

Call: SONATA 4 , Panel: NZ7

Principal investigator: dr Anna Krupa

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Cardioprotective effect of inhibitors of matrix metalloproteinase-2 (MMP-2) and inhibitors of posttanslational modificat...

Call: HARMONIA 3 , Panel: NZ3

Principal investigator: prof. Mieczysław Woźniak

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Effect of deimination of essential arginine residues on the function of protease inhibitors and other components of inna...

Call: OPUS 3 , Panel: NZ6

Principal investigator: dr Tomasz Kantyka

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Plasticity of the primary, the secondary, and the association auditory cortex in patients with partial deafness using th...

Call: PRELUDIUM 3 , Panel: NZ4

Principal investigator: Katarzyna Joanna Cieśla

Instytut Fizjologii i Patologii Słuchu

Impact of combined therapy of non-steroidal anti-inflammatory drugs and selective serotonin reuptake inhibitors on oxida...

Call: OPUS 3 , Panel: NZ5

Principal investigator: dr hab. Piotr Gałecki

Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski; Klinika Psychiatrii Dorosłych

Structure - activity relationship studies of new flavonoids derivatives as the inhibitors of the bacterial tyrosyl-tRNA ...

Call: PRELUDIUM 3 , Panel: NZ7

Principal investigator: dr Mirosława Anna Skupińska

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Neuroethics and Thomas Aquinas. On the Utility of Medieval Philosophy in Contemporary Ethical Debates

Call: OPUS 3 , Panel: HS1

Principal investigator: dr Piotr Lichacz

Instytut Filozofii i Socjologii Polskiej Akademii Nauk

Stilbene and stilbazole derivatives as potential cyclooxygenase-2 (COX-2) inhibitors with probable antitumor and chemopr...

Call: PRELUDIUM 1 , Panel: NZ4

Principal investigator: Miłosz Jakub Regulski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Stimulation of endogenous neurogenesis as a novel therapeutic strategy in neonatal hypoxic-ischemic brain injury.

Call: OPUS 3 , Panel: NZ3

Principal investigator: dr Małgorzata Nałęcz

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

The molecular basis of polyclonal expansion of regulatory T cells stimulated in vitro by retinoic acid

Call: PRELUDIUM 3 , Panel: NZ5

Principal investigator: dr Isaura Joanna Felcenloben

Uniwersytet Przyrodniczy we Wrocławiu, Wydział Medycyny Weterynaryjnej

The role of corticotropin releasing factor (CRF) in low and high anxiety rats, and teh iteraction between of the CRF sys...

Call: OPUS 3 , Panel: NZ7

Principal investigator: dr Anna Karolina Skórzewska

Instytut Psychiatrii i Neurologii

Diaminophosphonates as specific inhibitors of Neisseria meningitidis aminopeptidase N - synthesis and biological activit...

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: Ewelina Marta Węglarz-Tomczak

Politechnika Wrocławska, Wydział Chemiczny

The role of PML protein and PML nuclear bodies in adult mouse brain

Call: SONATA BIS 1 , Panel: NZ4

Principal investigator: prof. Grzegorz Marek Wilczyński

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

Evaluation of pharmacological activity of new, nonselective gamma-aminobutyric acid (GABA) transport inhibitors in some ...

Call: OPUS 3 , Panel: NZ7

Principal investigator: dr hab. Kinga Sałat

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Organometallic inhibitors of tubulin polymerisation. Synthesis, anticancer activities and tubulin affinities.

Call: OPUS 3 , Panel: ST5

Principal investigator: dr hab. Damian Plażuk

Uniwersytet Łódzki, Wydział Chemii

Experimental and simulation studies of advanced control of biotechnological processes stimulation

Call: OPUS 3 , Panel: ST7

Principal investigator: prof. Mieczysław Metzger

Politechnika Śląska, Wydział Automatyki, Elektroniki i Informatyki

Luminescent detectors of ionizing radiation based on silicate crystals

Call: PRELUDIUM 3 , Panel: ST8

Principal investigator: Anna Zuzanna Twardak

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

Modifications of aglycones of leucomycins via Michael addition and Huisgen dipolar cycloaddition as a new routes of synt...

Call: SONATA BIS 1 , Panel: ST5

Principal investigator: dr hab. Piotr Przybylski

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

Identification of amino acid residues located in positions P7 and P8 of model inhibitor of proprotein convertases that d...

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: Izabela Małuch

Uniwersytet Gdański, Wydział Chemii

Synthesis of mononucleotide N2,N2,7-trimethylguanosine cap analogues as translation inhibitors in Ascaris suum

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: dr Karolina Ewa Piecyk

Uniwersytet Warszawski, Wydział Chemii

The influence of metabolic pathway inhibitors on the development and quality of bovine embryos produced in vitro.

Call: OPUS 3 , Panel: NZ9

Principal investigator: dr hab. Dorota Marta Cieślak

Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

Pattern-Specific Inhibitors (PSI) - introduction and basic characteristics of a new class of inhibitors that block recog...

Call: OPUS 3 , Panel: NZ6

Principal investigator: dr Krzysztof Guzik

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

Call: SONATA 1 , Panel: ST5

Principal investigator: dr Joanna Kowalska

Uniwersytet Warszawski, Wydział Fizyki

Role of ruthenium complexes interaction with NO in the context of angiogenesis inhibition.

Call: PRELUDIUM 3 , Panel: ST5

Principal investigator: dr Maria Józefa Oszajca

Uniwersytet Jagielloński, Wydział Chemii

Peptide splicing - the mechanism and its application for designing compounds with potential use in medicinal practice

Call: OPUS 1 , Panel: ST5

Principal investigator: prof. Krzysztof Rolka

Uniwersytet Gdański, Wydział Chemii

Research into the understanding of a defense mechanism of wheat (Triticum aestivum) in response to feeding Oulema spp. -...

Call: OPUS 2 , Panel: NZ9

Principal investigator: dr hab. Aleksandra Julia Obrępalska-Stęplowska

Instytut Ochrony Roślin - Państwowy Instytut Badawczy

Solution NMR investigations of human cystatin C - structure, dynamics and protein-ligand interactions.

Call: PRELUDIUM 2 , Panel: ST4

Principal investigator: Martyna Ewa Maszota-Zieleniak

Uniwersytet Gdański, Wydział Chemii

Identifying of novel virus-encoded GW proteins that inhibit plant and animal RNAi-based defense systems.

Call: PRELUDIUM 2 , Panel: NZ2

Principal investigator: Andrzej Zieleziński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Hydrogen exchange mass spectrometry (HXMS) for studying human serum amyloid A fibril formation.

Call: PRELUDIUM 2 , Panel: NZ5

Principal investigator: Marta Sosnowska

Uniwersytet Gdański, Wydział Chemii

Mechanisms of anti-aterosclerotic action of Mas receptor stimulation for angiotensin 1-7 in mouse model of atheroscleros...

Call: PRELUDIUM 2 , Panel: NZ4

Principal investigator: Dominik Stanisław Skiba

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

New approaches towards modulating selective and functional activities of antisense oligonucleotides

Call: OPUS 2 , Panel: ST5

Principal investigator: prof. Ryszard Kierzek

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

Inter- and intracellular signalling in innate immune response: experimental and mathematical analysis

Call: OPUS 2 , Panel: NZ2

Principal investigator: prof. Tomasz Lipniacki

Instytut Podstawowych Problemów Techniki Polskiej Akademii Nauk

Novel urease inhibitors as means to control ureolytic microbial pathogens

Call: OPUS 2 , Panel: NZ6

Principal investigator: dr Agnieszka Grabowiecka

Politechnika Wrocławska

Developing histone deacetylase-inhibiting hybrid analogs of pleurocidin and their potential in the treatment of HPV-indu...

Call: SONATA 20 , Panel: NZ7

Principal investigator: dr hab. Ewelina Piktel

Uniwersytet Medyczny w Białymstoku

Novel insights into inhibition of PD-L1/PD-1 immune checkpoint – discovery and optimization of covalent PD-L1 inhibitors...

Call: SONATA 20 , Panel: ST5

Principal investigator: dr Radosław Dariusz Kitel

Uniwersytet Jagielloński

A new feature of the yeast Kazachstania humilis species: Growth-inhibitory properties against a broad spectrum of bacter...

Call: OPUS 28 , Panel: NZ9

Principal investigator: dr hab. Anna Sikora

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

Environmental modulation of CDK4/6 inhibitor efficacy: Impact of mycotoxin alternariol exposure on anti-cancer therapies

Call: SONATA 20 , Panel: NZ5

Principal investigator: dr Anna Dominika Walczak-Szeffer

Uniwersytet Medyczny w Łodzi

Advanced fiber-optic detectors based on the composite epitaxial structures of oxide compounds for radiation monitoring a...

Call: OPUS 28 , Panel: ST7

Principal investigator: prof. Yuriy Zorenko

Uniwersytet Kazimierza Wielkiego

Phytochemicals as inhibitors of polylactide's photooxidation and thermooxidation

Call: SONATA 20 , Panel: ST11

Principal investigator: dr Aleksander Mateusz Hejna

Politechnika Poznańska