Projects funded by the NCN

Novel aspects of virulence mechanisms of HopBF1, a bacterial effector that targets host HSP90 protein

Call: OPUS 19 , Panel: NZ1

Principal investigator: dr hab. Magdalena Krzymowska

Instytut Biochemii i Biofizyki PAN

Screening for new therapeutic targets in inherited retinal diseases based on protein-protein interactions analysis

Call: POLS , Panel: NZ4

Principal investigator: dr Xiaonan Liu

Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach

New multifunctional drug-like ligands focusing on molecular targets associated with the symptoms and causes of Alzheimer...

Call: PRELUDIUM 19 , Panel: NZ7

Principal investigator: Anna Marta Pasieka

Uniwersytet Jagielloński, Collegium Medicum

Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

Call: OPUS 19 , Panel: NZ1

Principal investigator: prof. Mariusz Jaskólski

Instytut Chemii Bioorganicznej PAN

Understanding of the mesenchymal stem cells (MSCs)-mediated immune suppression mechanism in the neutrophilic experimenta...

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: dr Marlena Tynecka

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

Call: OPUS 18 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

Instytut Farmakologii PAN

Exploring influence of inorganic cell microenvironment on NO signalling deregulation in age-related disorders. From mole...

Call: OPUS 18 , Panel: ST4

Principal investigator: prof. Grażyna Jolanta Stochel

Uniwersytet Jagielloński, Wydział Chemii

The 'omics' of renal cancer nucleolus: towards identification of new cancer markers and therapeutic targets.

Call: OPUS 18 , Panel: NZ5

Principal investigator: prof. Agnieszka Piekiełko-Witkowska

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO, Szkoła Nauk Medycznych

The importance of the crosstalk between alpha-synuclein and sphingosine-1-phosphate-dependent signalling in experimental...

Call: SONATINA 3 , Panel: NZ4

Principal investigator: dr Joanna Agata Motyl

Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza PAN

Multi-level molecular assessment based on laser microdissection of corneas to reveal biomarkers and therapeutic targets ...

Call: OPUS 16 , Panel: NZ5

Principal investigator: prof. Marzena Magdalena Gajęcka

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

Development of NALDI targets with application of chemically synthesized nanoparticles for detection of natural low molec...

Call: PRELUDIUM 16 , Panel: ST4

Principal investigator: Gulyaim Sagandykova

Uniwersytet Mikołaja Kopernika, Interdyscyplinarne Centrum Nowoczesnych Technologii

Determination of targets for peptidylarginine deiminase type 4 (PAD4) among complement system proteins and assessment of...

Call: HARMONIA 10 , Panel: NZ1

Principal investigator: dr Ewa Izabela Bielecka

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

Call: OPUS 15 , Panel: NZ7

Principal investigator: prof. Barbara Elżbieta Przewłocka

Instytut Farmakologii PAN

New targets for olefin metathesis: organometallic helices from achiral substrates

Call: OPUS 14 , Panel: ST5

Principal investigator: dr hab. Włodzimierz Krzysztof Buchowicz

Politechnika Warszawska, Wydział Chemiczny

Inhibitors of BTLA-HVEM complex formation as potential targets for cancer immunotheraphy

Call: SONATA 13 , Panel: ST5

Principal investigator: dr Marta Marcelina Spodzieja

Uniwersytet Gdański, Wydział Chemii

The enzymes of RNA metabolism, PAP I and PNPase, as targets for new antimycobacterial drugs and their functional charact...

Call: OPUS 13 , Panel: NZ7

Principal investigator: prof. Jarosław Dziadek

Instytut Biologii Medycznej PAN

RNA regulatory networks as novel antimicrobial targets in multidrugs resistant bacteria

Call: OPUS 13 , Panel: NZ6

Principal investigator: dr Marek Żywicki

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Identification of potential microRNA-328 targets and their role in the airway epithelial wound repair

Call: PRELUDIUM 13 , Panel: NZ3

Principal investigator: dr Beata Maria Narożna

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

Peroxiredoxins as potential therapeutic targets in glioblastoma.

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Monika Paulina Szeliga

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Identification and therapeutic use of proteasome machinery targets in human cancer

Call: OPUS 13 , Panel: NZ5

Principal investigator: dr Dawid Walerych

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Novel 2,4-disubstituted pyridine derivatives - synthesis, antimycobacterial activity in vitro, pharmacophore model, mole...

Call: OPUS 13 , Panel: NZ7

Principal investigator: dr hab. Katarzyna Małgorzata Gobis

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

Identification of Mycobacterium tuberculosis ligands binding human serum amyloid A (SAA) and biological function of tube...

Call: OPUS 12 , Panel: NZ7

Principal investigator: dr hab. Bożena Renata Dziadek

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

Call: PRELUDIUM 12 , Panel: NZ7

Principal investigator: Anna Piotrowska-Murzyn

Instytut Farmakologii PAN

Analysis of somatic mutations in miRNA and miRNA-biogenesis genes to identify new therapeutic targets and biomarkers of ...

Call: MAESTRO 8 , Panel: NZ2

Principal investigator: prof. Piotr Kozłowski

Instytut Chemii Bioorganicznej PAN

Conformational epitopes of canine leukocyte antigens DR (DLA-DR) as targets diagnosis and experimental therapy of lympho...

Call: PRELUDIUM 11 , Panel: NZ5

Principal investigator: Marta Lisowska

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Structural studies of signaling receptors HVEM/CD160 as potential targets for immunoterapy against melanoma

Call: SONATA 11 , Panel: NZ1

Principal investigator: dr Marta Orlikowska

Uniwersytet Gdański, Wydział Chemii

New 2(5H)-furanone derivatives with tailored hydrophobicity of substitutents - synthesis, molecular targets, mechanism o...

Call: OPUS 11 , Panel: NZ7

Principal investigator: prof. Krzysztof Zdzisław Walczak

Politechnika Śląska, Wydział Chemiczny

Regulation of energy sector in European Union and in Ukraine. Comparison od targets and legal measures of regulation in ...

Call: OPUS 11 , Panel: HS5

Principal investigator: dr hab. Eryk Kosiński

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Prawa i Administracji

Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa...

Call: OPUS 11 , Panel: NZ4

Principal investigator: prof. Joanna Gabriela Mika

Instytut Farmakologii PAN

Co-dependence of cell-to-cell metabolite shuttles and macromolecular organization of metabolism in norm and pathology. Q...

Call: OPUS 10 , Panel: NZ1

Principal investigator: prof. Dariusz Stanisław Rakus

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Experiment COMPASS - study of the three-dimensional and spin structure of the nucleon

Call: HARMONIA 7 , Panel: ST2

Principal investigator: prof. Andrzej Maciej Sandacz

Narodowe Centrum Badań Jądrowych

Novel pro-oxidative strategies in the treatment of B cell acute lymphoblastic leukemia

Call: SONATA BIS 5 , Panel: NZ5

Principal investigator: dr Małgorzata Firczuk

Warszawski Uniwersytet Medyczny, Wydział Lekarski

A coarse-grained model of protein - nanoparticles interactions for simulating the transport of drug molecules to their t...

Call: PRELUDIUM 9 , Panel: ST4

Principal investigator: dr Magdalena Anna Mozolewska

Uniwersytet Gdański, Wydział Chemii