Peroxiredoxins as potential therapeutic targets in glioblastoma.
2017/25/B/NZ7/00388
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN
Voivodeship: mazowieckie
Principal investigator (from the host institution)
dr hab. Monika Paulina Szeliga
Number of co-investigators in the project: 3
Call
OPUS 13 – announced on 2017-03-15
- Amount awarded
- 602 700 PLN
- Project start date
- 2018-01-19
- Project end date
- 2023-01-18
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Inkubator CO2. Cost: 45 000 PLN
Information in the final report
Publication in academic press/journals (3)
-
Comprehensive analysis of the expression levels and prognostic values of PRDX family genes in glioma.
- Authors:
- Szeliga M.
- Academic press:
- Neurochemistry International (year: 2022, volume: 153, pages: 105256), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.neuint.2021.105256 – link to the publication
-
Conoidin A, a covalent inhibitor of peroxiredoxin 2, reduces growth of glioblastoma cells by triggering ROS production.
- Authors:
- Szeliga M., Rola R.
- Academic press:
- Cells (year: 2023, volume: 12, pages: 1934), Publisher: mdpi
- Status:
- Published
- DOI:
- 10.3390/cells12151934. – link to the publication
-
Menadione potentiates auranofin-induced glioblastoma cell death.
- Authors:
- Szeliga M., Rola R.
- Academic press:
- Int J Mol Sci. (year: 2022, volume: 23, pages: 15712), Publisher: mdpi
- Status:
- Published
- DOI:
- 10.3390/ijms232415712. – link to the publication