Projects funded by the NCN


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96 projects found matching your search criteria :

  1. Assessment of the state and function of the brain cholinergic system in animal models of Alzheimer-type and frontotempor...

    Call: OPUS 8 , Panel: NZ4

    Principal investigator: dr hab. Grażyna Niewiadomska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  2. The physical properties of complexes of antibodies from the lipopolisaccharide form S and R strains of Proteus mirabilis...

    Call: PRELUDIUM 8 , Panel: NZ6

    Principal investigator: Joanna Maria Gleńska-Olender

    Uniwersytet Jana Kochanowskiego w Kielcach, Wydział Matematyczno-Przyrodniczy

  3. Search for early molecular mechanisms and markers of preclinical stage of sporadic form of Alzheimer's disease (SAD) in ...

    Call: SONATA 8 , Panel: NZ4

    Principal investigator: dr Anna Mietelska-Porowska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  4. The role of bioactive sphingolipids: ceramide, ceramide-1-phosphate and sphingosine-1-phosphate in regulation of mitocho...

    Call: OPUS 8 , Panel: NZ3

    Principal investigator: dr hab. Robert Piotr Strosznajder

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  5. Approach to structures of difficult protein targets using new mass spectrometry-based methods

    Call: MAESTRO 6 , Panel: NZ1

    Principal investigator: prof. Michał Lech Dadlez

    Instytut Biochemii i Biofizyki PAN

  6. Normal021falsefalsefalseMicrosoftInternetExplorer4/* Style Definitions */table.MsoNormalTable{mso-style-name:Standardowy...

    Call: PRELUDIUM 1 , Panel: NZ2

    Principal investigator: dr Maciej Suski

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  7. The influence of nanoparticles on beta-amyloid removal by microglia cells

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Katarzyna Sikorska

    Instytut Chemii i Techniki Jądrowej

  8. Inhibitors of ER stress dependant PERK kinase as a novel approach for Alzheimer's therapy

    Call: HARMONIA 5 , Panel: NZ1

    Principal investigator: prof. Ireneusz Jacek Majsterek

    Uniwersytet Medyczny w Łodzi, Wydział Wojskowo-Lekarski

  9. Conjugates of prion protein with dendrimers as inhibitors of Abeta peptide amyloidogenesis and cytotoxicity of potential...

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Krzysztof Nieznański

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  10. Searching for biological functions of APP family of proteins and APP-derived fragments in olfactory system.

    Call: OPUS 5 , Panel: NZ3

    Principal investigator: dr hab. Rafał Tomasz Butowt

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  11. The influence of dimethyl fumarate on the spatial memory, neurogenesis, neurodegeneration and cerebral imflammation in t...

    Call: SONATA 5 , Panel: NZ4

    Principal investigator: dr Irena Maria Majkutewicz

    Uniwersytet Gdański, Wydział Biologii

  12. Structural investigation of the active center of gamma-secretase and its interactions with selected substrates.

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Krzysztof Młynarczyk

    Uniwersytet Warszawski, Wydział Chemii

  13. Infective endocarditis - the in vitro biomedical analysis of the potential therapeutic properties of selected phytochemi...

    Call: PRELUDIUM 5 , Panel: NZ6

    Principal investigator: Bartłomiej Micota

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  14. FUNCTIONAL STUDIES OF RARE GENETIC VARIANTS OF GENES CAUSSALLY CONNECTED WITH ALZHEIMER'S DISEASE IN THE POLISH POPULATI...

    Call: SONATA 5 , Panel: NZ3

    Principal investigator: dr Michalina Maria Wężyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  15. Looking for the same pathological factors in ischemic brain and Alzheimer's disease;Genes

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Ryszard Pluta

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  16. Synthetic cysteine peptides as molecular layers for studies of interactions between copper ions and beta-amyloid

    Call: SONATA 4 , Panel: ST4

    Principal investigator: dr Urszula Elżbieta Wawrzyniak

    Politechnika Warszawska, Wydział Chemiczny

  17. Determination of physicochemical and biochemical propertiess of natural pyridine and piperidine alkaloids and their simp...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: dr Damian Andrzej Szczesny

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  18. Search of novel multifunctional ligands targeting neurodegereneration processes.

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Barbara Antonina Malawska

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  19. Functional, epigenetic and genetic aspects of base excision repair pathway in Alzheimer's disease

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  20. The role of acquired channelopathies in facilitationg post-traumatic epileptogenesis in APP/PS1 transgenic mice - an ani...

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Diana Miszczuk

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  21. An attempt to elucidate the role of clusterin and lipid rafts in Alzheimer's disease etiology.

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: prof. Arkadiusz Bernard Orzechowski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  22. Positioning the aryl hydrocarbon receptor (AhR) as a new target for pharmacotherapy of sporadic Alzheimer disease: verif...

    Call: OPUS 28 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kajta

    Instytut Farmakologii PAN

  23. Factors associated with a modulation of fibrin clot structure and resistance to fibrinolysis in patients with protein C ...

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: dr hab. Michał Tomasz Ząbczyk

    Krakowski Szpital Specjalistyczny im. Jana Pawła II

  24. Analysis of the effects of proteotoxic stress on cholesterol homeostasis and its associations with cardiovascular diseas...

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: prof. Wiesława Elżbieta Widłak

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  25. The first antibody-drug conjugates for Alzheimer's disease therapy

    Call: SONATA BIS 14 , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  26. Autophagy stimulation by genistein to cure Alzheimer disease: mechanisms and effects investigated using genetic (cellula...

    Call: OPUS 27 , Panel: NZ2

    Principal investigator: prof. Grzegorz Władysław Węgrzyn

    Uniwersytet Gdański

  27. Effect of phosphorylation of Aβ peptides on the redox activity oftheir copper complexes and aggregation in the context o...

    Call: SONATA 19 , Panel: ST4

    Principal investigator: dr Nina Ewa Wezynfeld

    Politechnika Warszawska, Wydział Chemiczny

  28. First-in-class dual modulators of necroptosis kinases and 5-HT6 receptors as an innovative approach to develop an effect...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Jadwiga Handzlik

    Uniwersytet Jagielloński, Collegium Medicum

  29. ROS-Scavenging Magnetic Nanozymes with Remote Activation for Alzheimer Disease

    Call: M-ERA.NET 3 Call 2023 , Panel: NZ5

    Principal investigator: dr hab. Anna Ludwika Haduch

    Instytut Farmakologii PAN

  30. Deciphering the Chemoproteomics and Chemotranscriptomics of Anti-Alzheimer Drugs for Novel Druggable Target Identificati...

    Call: JPND Call 2023 , Panel: NZ5

    Principal investigator: prof. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  31. (Micro)RNA and informatics approaches for diagnosis, prognosis and treatment of Alzheimer's disease and Dementia

    Call: JPND Call 2023 , Panel: NZ3

    Principal investigator: dr hab. Agnieszka Fiszer

    Instytut Chemii Bioorganicznej PAN

  32. Synthesis and biological activity evaluation of new hybrid derivatives of tacrine and melatonin as potential cholinester...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr Anna Zawadzka

    Uniwersytet Warszawski, Wydział Chemii

  33. Local molecular changes in amyloid-β altered by green tea's active compounds

    Call: PRELUDIUM 22 , Panel: ST4

    Principal investigator: Michał Andrzej Czaja

    Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  34. Blood plasma microRNA profile as a basis for detecting Alzheimer's disease and dementia risk in pre-symptomatic individu...

    Call: OPUS 24 , Panel: NZ7

    Principal investigator: prof. Urszula Wojda

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  35. Study of the regenerative potential of Stem Cells from Human Exfoliated Deciduous teeth (SHED) in Alzheimer's disease

    Call: POLONEZ BIS 3 , Panel: NZ3

    Principal investigator: dr Leila Elyasi

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  36. The role of CDK5 in inflammatory reaction in experimental model of Alzheimer's disease

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: dr hab. Grzegorz Arkadiusz Czapski

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  37. Defining (sex and age) cell-specific epigenetic mechanisms underlying EnvironmentalEnrichment/Exercise as non-pharmacolo...

    Call: JPND Call 2022 , Panel: NZ2

    Principal investigator: dr hab. Bartosz Zbigniew Wilczyński

    Uniwersytet Warszawski

  38. Selective modulation of PPARγ signaling as a new therapeutic strategy for Alzheimer's disease

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Karolina Barbara Przepiórska-Drońska

    Instytut Farmakologii PAN

  39. Combination of FAAH inhibition with action via serotonin 5-HT6 receptor as pioneering approach to fight with Alzheimer D...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: Kinga Maria Czarnota-Łydka

    Uniwersytet Jagielloński, Collegium Medicum

  40. Effects of activation of cholinergic, noradrenergic, and serotonergic systems on respiratory impairment in Alzheimer's d...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Kaczyńska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  41. Development of the knowledge on the role of GPR18 ligands as a microglia-targeted strategy in the regulation of neuroinf...

    Call: SONATA 17 , Panel: NZ3

    Principal investigator: dr Ewelina Barbara Honkisz-Orzechowska

    Uniwersytet Jagielloński, Collegium Medicum

  42. Bleomycin hydrolase, homocysteine metabolism, epigenetic regulation of mTOR signalling, autophagy, and Alzheimer's disea...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: dr hab. Joanna Perła-Kaján

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

  43. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  44. Research of multifunctional compounds targeting neuroinflammation and cholinergic deficit in Alzheimer's disease

    Call: OPUS 22 (LAP) , Panel: NZ7

    Principal investigator: prof. Kinga Aleksandra Sałat

    Uniwersytet Jagielloński, Collegium Medicum

  45. Presymptomatic synaptic disorders in Alzheimer's disease

    Call: JPco-fuND2 Call 2021 , Panel: NZ5

    Principal investigator: dr Michalina Maria Wężyk

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  46. Role of Amyloid Precursor Protein in the regulation of store-operated calcium entry

    Call: OPUS 2 , Panel: NZ3

    Principal investigator: dr Tomasz Sebastian Węgierski

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  47. Analysis of semaphorin 3 (SEMA3), protocadherin 9 (PCDH9) and S 100 calcium binding proteinA3 (S100A3) expression in pro...

    Call: OPUS 21 , Panel: NZ5

    Principal investigator: dr hab. Radosław Januchowski

    Uniwersytet Zielonogórski, Collegium Medicum

  48. Potential neuroprotective properties of modulators of sphingosine-1-phosphate (S1P) receptors (fingolimod and siponimod)...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Iga Wieczorek

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  49. Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Dawid Marcin Panek

    Uniwersytet Jagielloński, Collegium Medicum

  50. Mechanisms of host-pathogen interaction in the immune response of Galleria mellonella after infection with entomopathoge...

    Call: OPUS 1 , Panel: NZ6

    Principal investigator: dr hab. Iwona Elżbieta Wojda

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii