Projects funded by the NCN

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116 projects found matching your search criteria :

  1. Targeted inhibition of STATs and IRFs as a novel treatment strategy in cardiovascular disease

    Call: OPUS 9 , Panel: NZ2

    Principal investigator: prof. Johannes Antonius Bluijssen (Bluyssen)

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  2. Aromatic aminotransferases from Candida albicans as molecular targets for antifungal chemotherapy.

    Call: OPUS 9 , Panel: NZ6

    Principal investigator: dr Iwona Aniela Gabriel

    Politechnika Gdańska, Wydział Chemiczny

  3. Translation elongation as a target for regulation by non-coding RNAs in bacteria

    Call: OPUS 8 , Panel: NZ1

    Principal investigator: dr hab. Mikołaj Olejniczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  4. Identification and structural characterization of the primordial cytotoxic conformers of the amyloidogenic cascade: Idea...

    Call: UNISONO , Panel: NZ1

    Principal investigator: prof. Marek Cieplak

    Instytut Fizyki PAN

  5. Functional Characterization of Non-Collagenous Extracellular Matrix Proteins as a Potential Molecular Target and Novel B...

    Call: SONATA 8 , Panel: NZ5

    Principal investigator: dr Michał Andrzej Pawlak

    Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

  6. Next-generation sequencing of miRNA transcriptome and functional in vitro study: towards unravelling pathomechanisms and...

    Call: OPUS 8 , Panel: NZ2

    Principal investigator: prof. Michał Witt

    Instytut Genetyki Człowieka PAN

  7. Approach to structures of difficult protein targets using new mass spectrometry-based methods

    Call: MAESTRO 6 , Panel: NZ1

    Principal investigator: prof. Michał Lech Dadlez

    Instytut Biochemii i Biofizyki PAN

  8. Design and synthesis of probes for RabGGTase profiling and their application for identification of the site of phosphono...

    Call: SONATA BIS 4 , Panel: ST5

    Principal investigator: dr hab. Katarzyna Błażewska

    Politechnika Łódzka, Wydział Chemiczny

  9. Identification of proline metabolic pathway as a molecular target for experimental regulation of apoptosis/autophagy in ...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Jerzy Aleksander Pałka

    Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  10. Physicochemical characterization of cyclodextrins tailored for pH-dependent targeted therapy with anthracycline drugs

    Call: OPUS 7 , Panel: ST5

    Principal investigator: prof. Renata Bilewicz

    Uniwersytet Warszawski, Wydział Chemii

  11. Combined targeted therapy with the use of PPAR receptor ligands or statins and cytostatics aimed at molecular mechanisms...

    Call: SONATA 1 , Panel: NZ4

    Principal investigator: dr Wojciech Stanisław Placha

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

  12. New drug carriers in targeted anticancer therapy

    Call: OPUS 1 , Panel: ST5

    Principal investigator: prof. Artur Piotr Terzyk

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  13. Inhibition of p21-Activated Kinase (PAK) as a new molecular target in the treatment of chronic myeloid leukemia (CML)

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Sylwia Flis

    Narodowy Instytut Leków

  14. Motor thalamic nuclei as a potential therapeutic target for adenosine in parkinsonian and essential tremor; behavioural,...

    Call: OPUS 6 , Panel: NZ4

    Principal investigator: dr hab. Jadwiga Wardas

    Instytut Farmakologii PAN

  15. Synthesis, biological and biophysical evaluation of mRNA cap-peptide conjugates for targeted delivery of cap analogues t...

    Call: OPUS 6 , Panel: ST5

    Principal investigator: dr hab. Marzena Jankowska-Anyszka

    Uniwersytet Warszawski, Wydział Chemii

  16. BCL11b - Potential Therapeutic Target in T cell Neoplasms

    Call: OPUS 5 , Panel: NZ1

    Principal investigator: dr hab. Grzegorz Przybylski

    Instytut Genetyki Człowieka PAN

  17. The role of poly(ADP-ribose) polymerase and sirtuins in molecular mechanism of cell death. Identification of novel targe...

    Call: OPUS 5 , Panel: NZ3

    Principal investigator: prof. Joanna Benigna Strosznajder

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  18. High throughput determination of RNA targets for MBNL1 splicing factor - Implication for myotonic dystrophy

    Call: OPUS 1 , Panel: NZ1

    Principal investigator: dr hab. Krzysztof Sobczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  19. Evaluation of peroxiredoxins 1 and 2 along with the thioredoxin-thioredoxin reductase system as new therapeutic targets ...

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: dr hab. Radosław Zagożdżon

    Warszawski Uniwersytet Medyczny, I Wydział Lekarski

  20. Characterization of CD44/p53 signaling involved in the CD44-dependent cancer stem cells: small molecules and peptides, t...

    Call: MAESTRO 3 , Panel: ST5

    Principal investigator: prof. Tadeusz Andrzej Holak

    Uniwersytet Jagielloński, Wydział Chemii

  21. Identification of potential therapeutic targets in melanoma stem-like cells

    Call: HARMONIA 3 , Panel: NZ2

    Principal investigator: prof. Małgorzata Ewa Czyż

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski z Oddziałem Stomatologicznym

  22. Carbon nanotubes as magnetic nanocariers in the targeted chemotherapy

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr hab. Sławomir Boncel

    Politechnika Śląska, Wydział Chemiczny

  23. Steady states in confined microscopic systems: auxetic micro-slits and stimuli sensitive microgel particles in microchan...

    Call: OPUS 3 , Panel: ST3

    Principal investigator: dr hab. Arkadiusz Cezary Brańka

    Instytut Fizyki Molekularnej PAN

  24. Multitasking polymeric lattices included selected DNA oligonucleotide sequences - synthesis, modifications and physioche...

    Call: SONATA 3 , Panel: ST5

    Principal investigator: dr Ewelina Zabost

    Uniwersytet Warszawski, Wydział Chemii

  25. Studies on non-linear laser-plasma interactions and generation of shocks in plasma for shock ignition of inertially conf...

    Call: HARMONIA 2 , Panel: ST2

    Principal investigator: prof. Jan Bronisław Badziak

    Instytut Fizyki Plazmy i Laserowej Mikrosyntezy im. Sylwestra Kaliskiego

  26. Pathogenesis of ovarian cancer survival in non-adhesion conditions: transcriptomic assessment and studies of molecular t...

    Call: PRELUDIUM 2 , Panel: NZ1

    Principal investigator: dr Anna Stachurska

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  27. Targeted Degradation of the MLL Complex in Leukemia: A PROTAC-Based Therapeutic Strategy

    Call: SONATINA 9 , Panel: ST5

    Principal investigator: dr Natalia Anna Skrzypczak

    Fundacja Uniwersytetu im. Adama Mickiewicza

  28. Identifying early biomarkers and molecular targets for therapeutic intervention in right ventricular dysfunction

    Call: OPUS 28 , Panel: NZ5

    Principal investigator: prof. Przemysław Błyszczuk

    Uniwersytet Jagielloński

  29. Tick-borne encephalitis virus protease as a molecular target for novel inhibitors and activity-based probes

    Call: OPUS 28 , Panel: NZ6

    Principal investigator: dr Renata Grzywa

    Politechnika Wrocławska

  30. Application of bioconjugation strategy to the synthesis of anticancer Trojan horses

    Call: OPUS 28 , Panel: ST5

    Principal investigator: dr hab. Michał Piotr Antoszczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu

  31. The H3K27M oncohistone-centred molecular mechanisms as therapeutic targets in pediatric malignant diffuse midline glioma...

    Call: SONATA BIS 14 , Panel: NZ3

    Principal investigator: dr Katarzyna Leszczyńska

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  32. Quad-TNT: Quadruplex-Targeted Photo-Therapy for Triple-Negative Tumors

    Call: SONATA BIS 14 , Panel: NZ5

    Principal investigator: dr Marco Deiana

    Politechnika Wrocławska

  33. Cellular effects in the tumor microenvironment and the potential for targeted delivery of molecules associated with the ...

    Call: OPUS 27 , Panel: NZ4

    Principal investigator: prof. Magdalena Maria Staniszewska

    Katolicki Uniwersytet Lubelski Jana Pawła II

  34. Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Tadeusz Holak

    Uniwersytet Gdański

  35. CD147 as a novel multifunctional modulator of podocyte metabolism and exosome biogenesis: Identification of new molecula...

    Call: OPUS 27 , Panel: NZ4

    Principal investigator: dr hab. Agnieszka Piwkowska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  36. Two-body currents in the electron and neutrino scattering off few-nucleon targets

    Call: IMPRESS-U , Panel: ST2

    Principal investigator: prof. Jacek Golak

    Uniwersytet Jagielloński

  37. Radiolabelled up-converting nanoparticles as theranostic agents for multimodal imaging and targeted therapy

    Call: SONATINA 8 , Panel: ST5

    Principal investigator: dr Karolina Kinga Zajdel

    Narodowe Centrum Badań Jądrowych

  38. Stimuli-responsive anion transporters for targeted drug delivery

    Call: OPUS 26 , Panel: ST5

    Principal investigator: dr hab. Michał Jan Chmielewski

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  39. Activation of Staphylococcus aureus LytM autolysin as a potential target for antimicrobials development.

    Call: OPUS 26 , Panel: NZ1

    Principal investigator: dr hab. Izabela Sabała

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  40. Restoring Beta-cell Integrity through Targeted SPOP Inhibition and PDX-1 Preservation

    Call: OPUS 26 (LAP) , Panel: NZ7

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  41. Integrated multi-omics approach to accelerate anticancer drug discovery by targeting metabolic reprogramming in human co...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Danuta Dudzik

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  42. Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Izabela Siekierska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  43. Senolytic nanoplatform to target and eliminate skin cancer Zombie cells

    Call: M-ERA.NET 2022 , Panel: ST5

    Principal investigator: dr hab. Anna Karolina Lewińska

    Uniwersytet Rzeszowski, Kolegium Nauk Przyrodniczych

  44. Targeted drug delivery systems - synthesis and functionalization of nanocarriers

    Call: SONATA 2 , Panel: ST5

    Principal investigator: dr Krzysztof Szczepanowicz

    Instytut Katalizy i Fizykochemii Powierzchni im. Jerzego Habera PAN

  45. Molecular insights into hypoxic tumors – for development of targeted cancer therapeutics

    Call: POLONEZ BIS 3 , Panel: NZ5

    Principal investigator: dr Marco Deiana

    Politechnika Wrocławska

  46. Modifiers of Muscleblind-like genes expression in health and disease.

    Call: SONATA BIS 12 , Panel: NZ5

    Principal investigator: dr hab. Ewa Agnieszka Stępniak-Konieczna

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Rolnictwa, Ogrodnictwa i Biotechnologii

  47. Computational deciphering of pro-ferroptotic cell death protein machinery as a fundamental step in the search for therap...

    Call: SONATA BIS 12 , Panel: ST4

    Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  48. Early-life programming for neurodevelopmental disorders: search for a prodrome target within the vascular network in a r...

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  49. Yeast DNA topoisomerase II as a model molecular target for novel antifungalcompounds

    Call: OPUS 23 , Panel: NZ6

    Principal investigator: dr hab. Iwona Aniela Gabriel

    Politechnika Gdańska, Wydział Chemiczny

  50. Synthesis of new phthalocyanines for targeted photodynamic cancer therapy.

    Call: SONATA 2 , Panel: ST5

    Principal investigator: dr Łukasz Andrzej Łapok

    Uniwersytet Jagielloński, Wydział Chemii; Zespół Nanotechnologii Polimerów i Biomateriałów

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