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Modulation of molecular pathways by pharmacological mitochondria-targeting hydrogen sulfide donor in chronic gastric ulcer healing process

2020/37/N/NZ4/04192

Keywords:

hydrogen sulfide mitochondria peptic ulcer disease gastrointestinal pathophysiology and pharmacology

Descriptors:

  • NZ4_004:
  • NZ5_007:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Collegium Medicum

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Dagmara Ewa Wójcik-Grzybek 

Number of co-investigators in the project: 3

Call: PRELUDIUM 19 - announced on 2020-03-16

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2021-02-11

Project end date (Y-m-d): 2026-02-10

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Articles in post-conference publications (3)
  1. Novel approach on peptic ulcer pharmacology: therapeutic effect of mitochondria-targeted hydrogen sulfide molecules
    Authors:
    Dagmara Wójcik-Grzybek, Zbigniew Sliwowski, Aleksandra Danielak, Grzegorz Ginter, Tomasz Futyma, Slawomir Kwiecien, Jakub Cieszkowski, Katarzyna Magierowska, Anna Chmura, Matthew Whiteman, Marcin Magierowski
    Conference:
    Gastroenterology, Volume 164, Issue 6, Supplement, May 2023 (rok: 2023, tom: Digestive Disease Week® 2023, strony: S-595-S-596), Wydawca: Elsevier
    Data:
    konferencja 6-9 maja 2023
    Status:
    Published
    DOI:
    10.1016/S0016-5085(23)02390-9 - link to the publication
  2. Therapeutic effect of mitochondria-targeting hydrogen sulfide prodrug, AP39 in the healing of chronic gastric ulcer
    Authors:
    Dagmara Wójcik-Grzybek, Zbigniew Sliwowski, Grzegorz Ginter, Katarzyna Magierowska, Aleksandra Danielak, Slawomir Kwiecien, Jakub Cieszkowski, Tomasz Futyma, Anna Chmura, Matthew Whiteman, Marcin Magierowski
    Conference:
    Gastroenterology, Volume 162, Issue 7, Supplement, May 2022 (rok: 2022, tom: Digestive Disease Week® 2022, strony: S-315), Wydawca: Elsevier
    Data:
    konferencja 21-24 maja 2022
    Status:
    Published
    DOI:
    10.1016/S0016-5085(22)60756-X - link to the publication
  3. Therapeutic effect of mitochondria-targeting hydrogen sulfide prodrug, AP39 in the healing of chronic gastric ulcer
    Authors:
    Dagmara Wójcik-Grzybek, Zbigniew Sliwowski, Grzegorz Ginter, Katarzyna Magierowska, Aleksandra Danielak, Slawomir Kwiecien, Jakub Cieszkowski, Tomasz Futyma, Anna Chmura, Matthew Whiteman, Marcin Magierowski
    Conference:
    Gastroenterology, Volume 162, Issue 7, Supplement, May 2022 (rok: 2022, tom: Digestive Disease Week® 2022, strony: S-315), Wydawca: Elsevier
    Data:
    konferencja 21-24 maja 2022
    Status:
    Published
    DOI:
    10.1016/S0016-5085(22)60756-X - link to the publication

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