Search results

51. EFFECTS OF ADENOSINE A2A RECEPTOR LIGANDS ON BEHAVIORAL EFFECTS OF ABUSED DRUG (COCAINE) AND NATURAL REWARD (FOOD) USING…

Principal investigator: Karolina Agnieszka Wydra

Instytut Farmakologii PAN

Call: PRELUDIUM 2, Panel: NZ7

52. New bioinformatics method for predicting ligand-binding sites in RNA structures

Principal investigator: dr Anna Philips

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Call: PRELUDIUM 2, Panel: NZ2

53. Electronic Structure and Electron Transfer Reactions in Selected Molecular Prototypes Involving Non-innocent Ligands: An…

Principal investigator: dr Piotr Paweł Zarzycki

Instytut Chemii Fizycznej Polskiej Akademii Nauk

Call: OPUS 2, Panel: ST5

54. Development of a method for the structure prediction of GPCRs complexes with agonists and antagonists, including the lig…

Principal investigator: dr Michał Koliński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 1, Panel: NZ2

55. Combined targeted therapy with the use of PPAR receptor ligands or statins and cytostatics aimed at molecular mechanisms…

Principal investigator: dr Wojciech Stanisław Placha

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski

Call: SONATA 1, Panel: NZ4

56. New optically active thio- and selenphosphinic acids as chiral solvating agents in NMR spectoscopy , ligands in complexe…

Principal investigator: prof. Józef Drabowicz

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 1, Panel: ST5

57. Reversible modulation of G-quadruplex functions using photoresponsive ligands - in vitro and cellular studies

Principal investigator: dr Marta Maria Dudek

Politechnika Wrocławska

Call: SONATA 17, Panel: ST4

58. Towards novel ZnO quantum dots coated with mixed-ligand shell

Principal investigator: Anna Natalia Wojewódzka

Politechnika Warszawska, Wydział Chemiczny

Call: PRELUDIUM 15, Panel: ST5

59. Functional selectivity of novel histamine H4 receptor ligands

Principal investigator: Agnieszka Urszula Olejarz-Maciej

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 12, Panel: NZ7

60. Theoretical studies on the mechanism of the CO2/epoxide copolimerization with bifunctional catalysts based on Co(III) co…

Principal investigator: prof. Artur Michalak

Uniwersytet Jagielloński, Wydział Chemii

Call: OPUS 6, Panel: ST4

61. New ligands with P-P bond - synthesis and structural investigations

Principal investigator: prof. Jerzy Paweł Pikies

Politechnika Gdańska, Wydział Chemiczny

Call: HARMONIA 3, Panel: ST5

62. Functional nanomaterials based on drug–lipid–ligands as targeted delivery systems for anticancer agents in lung adenocar…

Principal investigator: Piotr Paweł Szyk

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Call: PRELUDIUM 24, Panel: NZ7

63. Acyclic aminocarbenes and acyclic aminooxycarbenes as useful ligands for ruthenium complexes

Principal investigator: dr hab. Anna Sylwia Kajetanowicz

Uniwersytet Warszawski

Call: OPUS 28, Panel: ST4

64. L-SWITCH: towards tailor-made molecular switches for specific applications – understanding of transition-metal coordinat…

Principal investigator: dr hab. Katarzyna Natalia Jarzembska

Uniwersytet Warszawski

Call: OPUS 28, Panel: ST4

65. Cyclic triel carbenoids as auxiliary ligands for ruthenium-based olefin metathesis catalysts

Principal investigator: Tymoteusz Marek Basak

Uniwersytet Warszawski

Call: PRELUDIUM 23, Panel: ST4

66. Cobalt and Iron Complexes With Aminophosphine Ligands: Catalysts Design for Organic and Organometallic Synthesis

Principal investigator: dr Hanna Maria Stachowiak-Dłużyńska

Fundacja Uniwersytetu im. Adama Mickiewicza

Call: SONATINA 8, Panel: ST4

67. Crownphyrins - hybrids of crown ethers and porphyrins, constituting macrocyclic platforms for the construction of two- a…

Principal investigator: dr hab. Bartosz Jakub Szyszko

Uniwersytet Wrocławski, Wydział Chemii

Call: PRELUDIUM BIS 5, Panel: ST4

68. "I like to move it, move it" – molecular dynamics-driven optimization of ligand residence time as an opportunity to impr…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 25, Panel: NZ7

69. Metallocarbaporphyrinoids as ligands in monomeric and oligomeric complexes. Synthesis, interactions, and catalysis.

Principal investigator: prof. Piotr Jan Chmielewski

Uniwersytet Wrocławski, Wydział Chemii

Call: OPUS 23, Panel: ST4

70. Novel tricyclic glycomimetics as DC-SIGN receptor ligands.

Principal investigator: dr Mykhaylo Potopnyk

Instytut Chemii Organicznej Polska Akademia Nauk

Call: OPUS 22, Panel: ST4

71. Development of the knowledge on the role of GPR18 ligands as a microglia-targeted strategy in the regulation of neuroinf…

Principal investigator: dr Ewelina Barbara Honkisz-Orzechowska

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ3

72. Targeting cell surface proteoglycans with high affinity multimeric ligands and their cytotoxic conjugates – towards prec…

Principal investigator: dr hab. Łukasz Opaliński

Uniwersytet Wrocławski, Wydział Biotechnologii

Call: OPUS 22, Panel: NZ1

73. Studies on anti-inflammatory properties of GPR18 ligands and their involvement in modulation of microglia phenotypes – a…

Principal investigator: dr hab. Dorota Justyna Łażewska

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 22, Panel: NZ7

74. The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami…

Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

Call: SONATA 17, Panel: NZ7

75. True Bioisosteres - Structural and Thermodynamic Classification of Molecular Fragments for Ligand Design

Principal investigator: dr Maura Dagmara Malińska

Uniwersytet Warszawski, Wydział Chemii

Call: SONATA BIS 11, Panel: ST4

76. Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors.

Principal investigator: dr hab. Paweł Aleksander Siedlecki

Instytut Biochemii i Biofizyki PAN

Call: OPUS 20, Panel: ST4

77. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan…

Principal investigator: prof. Andrzej Mikołaj Pilc

Instytut Farmakologii PAN

Call: OPUS 19, Panel: NZ7

78. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system…

Principal investigator: dr Katarzyna Anna Szczepańska

Instytut Farmakologii PAN

Call: SONATINA 4, Panel: NZ7

79. Do potential new MRGPRX2 ligands induce mastocytes degranulation in human?

Principal investigator: dr hab. Grzegorz Porębski

Uniwersytet Jagielloński, Collegium Medicum

Call: OPUS 18, Panel: NZ5

80. MXO2-ISOMER: in search of colour-changing photoswitchable materials based on 4th-row transition-metal complexes with sim…

Principal investigator: dr hab. Katarzyna Natalia Jarzembska

Uniwersytet Warszawski, Wydział Chemii

Call: PRELUDIUM BIS 1, Panel: ST4

81. Neuroprotective properties of 5-HT6 receptor ligands in the group of 2-arylpyrrole derivatives – a new insight into neur…

Principal investigator: Marcin Józef Drop

Uniwersytet Jagielloński, Collegium Medicum

Call: PRELUDIUM 17, Panel: NZ7

82. Development of new and more efficient treatment against mesothelioma utilizing oncolytic adenovirus armed with ICOS liga…

Principal investigator: dr Łukasz Kuryk

Narodowy Instytut Zdrowia Publicznego - Państwowy Zakład Higieny (NIZP - PZH)

Call: SONATINA 3, Panel: NZ7

83. Searching for effective strategies to protect neuronal cells against hypoxia and ischemia: Identification of neuroprotec…

Principal investigator: prof. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ7

84. Biased multi-target ligands as tools for activity pattern analysis of G protein-coupled receptors in cancer cells

Principal investigator: dr Artur Wnorowski

Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny z Oddziałem Analityki Medycznej

Call: SONATA 14, Panel: NZ7

85. Synthesis and physicochemical properties of novel functional metal-organic compounds based on hypophosphite ligands

Principal investigator: prof. Mirosław Robert Mączka

Instytut Niskich Temperatur i Badań Strukturalnych im. Włodzimierza Trzebiatowskiego PAN

Call: OPUS 16, Panel: ST5

86. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st…

Principal investigator: dr hab. Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: OPUS 16, Panel: NZ2

87. Thymol-derived 1,3,5-triazines, the non-indole and non-sulfone 5-HT6 receptor ligands, as a starter in search for an inn…

Principal investigator: prof. Jadwiga Handzlik

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 16, Panel: NZ7

88. Modeling of glycosaminoglycan-induced formation of protein structure and enhancement of biologically relevant protein-li…

Principal investigator: dr Sergey Samsonov

Uniwersytet Gdański, Wydział Chemii

Call: SONATA BIS 8, Panel: ST4

89. Multifunctional ligands - TRPA1 channel antagonists and phosphodiesterases inhibitors as a new approach for the treatmen…

Principal investigator: prof. Grażyna Chłoń-Rzepa

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 15, Panel: NZ7

90. NCN-cyklometalujące ligandy pirenowe oraz ligandy tridentne w syntezie mono- i binuklearnych związków kompleksowych

Principal investigator: Dawid Mariusz Zych

UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

Call: ETIUDA 6, Panel: ST5

91. The effect of peroxisome proliferator-activated receptor gamma (PPARy) ligands on the transrciptome and proteome profile…

Principal investigator: Zuzanna Kunicka

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

Call: PRELUDIUM 14, Panel: NZ9

92. Small-molecule inhibitors for characterization of the interaction between extracellular domains of Programmed Cell Death…

Principal investigator: prof. Tadeusz Andrzej Holak

Uniwersytet Jagielloński, Wydział Chemii

Call: MAESTRO 9, Panel: ST5

93. Predicting affinity of ligands to RNA. The case of an aminoglycoside-sensing riboswitch.

Principal investigator: prof. Joanna Dominika Trylska

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Call: HARMONIA 9, Panel: NZ1

94. Intracellular cross-talk between ligands and Notch receptors determine signalling response

Principal investigator: prof. Adolfo Rivero-Muller

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

Call: OPUS 13, Panel: NZ4

95. Novel ligands of histamine receptor H4 as potential anti-allergic and anti-inflammatory drugs

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 13, Panel: NZ7

96. Development of an NK1 receptor homology model based on the data concerning interspecies differences in ligand binding.

Principal investigator: dr Piotr Jakub Lipiński

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: SONATA 12, Panel: NZ7

97. Structural determinants of optical control of insulin and neuroligin release by photoactive protein ligands.

Principal investigator: prof. Wiesław Nowak

Uniwersytet Mikołaja Kopernika, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: OPUS 12, Panel: ST4

98. New perspective in Alzheimer's disease therapy - multifunctional histamine H3 receptor ligands?

Principal investigator: dr hab. Dorota Łażewska

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: OPUS 12, Panel: NZ7

99. Study of mechanism of proteolysis and a selective ligand binding to gamma-secretase complex

Principal investigator: prof. Sławomir Hubert Filipek

Uniwersytet Warszawski, Wydział Chemii

Call: OPUS 12, Panel: NZ2

100. New mulitple target-directed ligands - A1/A2A adenosine receptors antagonists and monoamine oxidase B inhibitors - searc…

Principal investigator: Michał Karol Załuski

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Call: PRELUDIUM 12, Panel: NZ7

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