Reversible modulation of G-quadruplex functions using photoresponsive ligands - in vitro and cellular studies
2021/43/D/ST4/00997
Keywords
Descriptors
- ST4_009: Chemia biologiczna
- ST4_012: Fotochemia
- ST4_002: Metody spektroskopowe i spektrometryczne
Panel
ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution
Politechnika Wrocławska
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
SONATA 17 – announced on 2021-09-15
- Amount awarded
- 1 052 128 PLN
- Project start date
- 2022-07-01
- Project end date
- 2027-05-31
- Project duration
- 59 months (the same as in the proposal)
- Project status
- Pending project
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (4)
-
A Rationally Designed Azobenzene Photoswitch for DNA G-Quadruplex Regulation in Live Cells
- Authors:
- Marta Dudek, Lucía López-Pacios, Nasim Sabouri, Juan J. Nogueira, Lara Martinez-Fernandez, Marco Deiana
- Academic press:
- Angewandte Chemie International Edition (year: 2024, volume: 64, pages: e202413000), Publisher: Wiley-VCH
- Status:
- Published
- DOI:
- 10.1002/anie.202413000 – link to the publication
-
Tunable G-quadruplex ligands: azobenzene derivatives for light-controlled DNA modulation
- Authors:
- Aleksandra A. Matusiak, Mateusz P. Drąg, Marco Deiana, Mikołaj Janicki, Marta M. Dudek
- Academic press:
- Chemistry- A European Journal (year: 2025, volume: 31, pages: e202404365), Publisher: Wiley-VCH
- Status:
- Published
- DOI:
- 10.1002/chem.202404365 – link to the publication
-
Light-Activated Molecules Targeting G-Quadruplex Nucleic Acids
- Authors:
- Marta Dudek, Clément Cabanetos, Marco Deiana
- Academic press:
- Chemistry- A European Journal (year: 2025, volume: 31, pages: e202501545), Publisher: Wiley-VCH
- Status:
- Published
- DOI:
- 10.1002/chem.202501545 – link to the publication
-
Harnessing Light for G‑Quadruplex Modulation: Dual Isomeric Effects of an Ortho-Fluoroazobenzene Derivative
- Authors:
- Marta Dudek, Lucía López-Pacios, Nasim Sabouri, Juan J. Nogueira, Lara Martinez-Fernandez, Marco Deiana
- Academic press:
- The Journal of Physical Chemistry Letters (year: 2024, volume: 15, pages: 9757−9765), Publisher: American Chemical Society
- Status:
- Published
- DOI:
- 10.1021/acs.jpclett.4c02285 – link to the publication