Projects funded by the NCN
Reversible modulation of G-quadruplex functions using photoresponsive ligands - in vitro and cellular studies
2021/43/D/ST4/00997
Keywords:
molecular switches photoisomerization DNA binders G-quadruplex supramolecular chemistry photoswitching DNA regulation spectroscopy
Descriptors:
- ST4_009:
- ST4_012:
- ST4_002:
Panel:
ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development
Host institution :
Politechnika Wrocławska
woj. dolnośląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 4
Call: SONATA 17 - announced on 2021-09-15
Amount awarded: 1 052 128 PLN
Project start date (Y-m-d): 2022-07-01
Project end date (Y-m-d): 2026-06-30
Project duration:: 48 months (the same as in the proposal)
Project status: Pending project
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- A Rationally Designed Azobenzene Photoswitch for DNA G-Quadruplex Regulation in Live CellsAuthors:Marta Dudek, Lucía López-Pacios, Nasim Sabouri, Juan J. Nogueira, Lara Martinez-Fernandez, Marco DeianaAcademic press:Angewandte Chemie International Edition (rok: 2024, tom: 64, strony: e202413000), Wydawca: Wiley-VCHStatus:PublishedDOI:10.1002/anie.202413000 - link to the publication
- Harnessing Light for G‑Quadruplex Modulation: Dual Isomeric Effects of an Ortho-Fluoroazobenzene DerivativeAuthors:Marta Dudek, Lucía López-Pacios, Nasim Sabouri, Juan J. Nogueira, Lara Martinez-Fernandez, Marco DeianaAcademic press:The Journal of Physical Chemistry Letters (rok: 2024, tom: 15, strony: 9757−9765), Wydawca: American Chemical SocietyStatus:PublishedDOI:10.1021/acs.jpclett.4c02285 - link to the publication