Projects funded by the NCN


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35 projects found matching your search criteria :

  1. Selected antidepressants toxicity assessment based on in vitro studies of rat spermatocytes and mouse cell lines.

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Przemysław Sołek

    Uniwersytet Rzeszowski, Wydział Biotechnologii

  2. Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha...

    Call: PRELUDIUM 7 , Panel: NZ6

    Principal investigator: Katarzyna Curzytek

    Instytut Farmakologii PAN

  3. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  4. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN

  5. Synthesis of pyridopyrimidine derivatives, dual affinity ligands for 5-HT1AR and SERT.

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Franciszek Herold

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  6. Antidepressats as substances that increase the activity of risperidone, an atypical antipsychotic drug in animal models

    Call: PRELUDIUM 5 , Panel: NZ7

    Principal investigator: Katarzyna Kamińska

    Instytut Farmakologii PAN

  7. The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  8. Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Magdalena Sowa-Kućma

    Instytut Farmakologii PAN

  9. Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d...

    Call: OPUS 4 , Panel: NZ4

    Principal investigator: dr Maciej Kuśmider

    Instytut Farmakologii PAN

  10. The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Joanna Solich

    Instytut Farmakologii PAN

  11. Role of the endocannabionoid system in the pathogenesis of depression and in the mechanism of action of antidepressant d...

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: prof. Małgorzata Filip

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  12. Evaluation of the role of subpopulations of T lymphocytes (Treg: CD4+CD25+, CD4+CD25- i Teff: Th2) in depression using p...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Sylwia Kędracka-Krok

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  13. Optogenetic and chemogenetic identification of brain circuits and cellular mechanisms underlying antidepressants resista...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  14. The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Andrzej Pilc

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  15. The role of GPR39 receptor in the mechanism of antidepressant action

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Katarzyna Młyniec

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  16. Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

    Call: OPUS 22 , Panel: HS6

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  17. The role of the immune checkpoints in the pathomechanism of depressive disorders.

    Call: OPUS 22 , Panel: NZ6

    Principal investigator: prof. Marta Kubera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  18. Metabolic stability and inhibition of P450 enzymes in combination with chemometric techniques as a tool for selection of...

    Call: OPUS 2 , Panel: NZ1

    Principal investigator: prof. Tomasz Bączek

    Gdański Uniwersytet Medyczny, Wydział Farmcautyczny z Oddziałem Medycyny Laboratoryjnej

  19. Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Katarzyna Głombik

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  20. The influence of microplastics on the toxicity and fate of selected antidepressants

    Call: OPUS 18 , Panel: NZ8

    Principal investigator: prof. Grzegorz Nałęcz-Jawecki

    Warszawski Uniwersytet Medyczny

  21. Novel pharmacological strategies for the treatment of depression

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Młyniec

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  22. The role of selected metabotropic glutamate receptors in the mechanism of rapid antidepressant effect of RS-ketamine and...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  23. Pharmacological and optogenetic investigation of the mechanism of action of Deep Brain Stimulation of the ventromedial p...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  24. Zinc Deficiency: An essential Variable for the Induction od Resistance to Antidepressants

    Call: PRELUDIUM 13 , Panel: NZ5

    Principal investigator: dr Anna Rafało-Ulińska

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  25. Role of oxidative stress and ceramide in the pathogenesis of depression and in the mechanizm of action of antidepressant...

    Call: PRELUDIUM 12 , Panel: NZ5

    Principal investigator: Justyna Brodowicz

    Instytut Farmakologii Polskiej Akademii Nauk

  26. Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Zofia Rogóż

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  27. Modeling of quantitative structure-metabolic stability relationships as a tool to improve design of potential novel anti...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Tomasz Bączek

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  28. Effect of modulation of the GPR39 zinc receptor on glutamatergic and gabaergic transmission in the context of antidepres...

    Call: PRELUDIUM 11 , Panel: NZ7

    Principal investigator: Gabriela Starowicz

    Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

  29. The importance of interaction between NMDA and AMPA receptors and scaffolding proteins in the excitatory synaptic in the...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: dr hab. Magdalena Sowa-Kućma

    Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

  30. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Karolina Podkowa

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  31. The role of inflammation, oxidative and nitrosative stress, tryptophan catabolites pathway and DNA base excision repair ...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  32. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Irena Nalepa

    Instytut Farmakologii PAN

  33. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  34. The application of a modern chromatographic platform with biodetection: HPLC-DAD/MAO A/ESI-TOF-MS in the antidepressant ...

    Call: SONATA 9 , Panel: NZ7

    Principal investigator: dr hab. Wirginia Kukuła-Koch

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  35. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

    Call: PRELUDIUM 9 , Panel: NZ7

    Principal investigator: dr Ewa Trojan

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk