Projects funded by the NCN


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208 projects found matching your search criteria :

  1. Chemical effects in targeted drug delivery: The roles of anticancer drugs, carriers and conjugates on biomimetic membran...

    Call: SONATA 12 , Panel: ST4

    Principal investigator: dr Dorota Maria Nieciecka

    Uniwersytet Warszawski, Wydział Chemii

  2. Modeling of quantitative structure-metabolic stability relationships as a tool to improve design of potential novel anti...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Tomasz Bączek

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  3. Evaluation of primary and secondary molecular disorders determinig drug resistance from a group of proteasome inhibitors...

    Call: OPUS 12 , Panel: NZ5

    Principal investigator: prof. Tadeusz Jerzy Robak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  4. Identification of the mechanism of sensitization of human ovarian cancer cells to anticancer drugs by the DNA double str...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Macieja

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  5. Pharmacogenetics of thiopurine drugs in patients with inflammatory bowel disease - application of the newest methods of ...

    Call: SONATA 12 , Panel: NZ2

    Principal investigator: dr Marzena Skrzypczak-Zielińska

    Instytut Genetyki Człowieka PAN

  6. Evaluation of SLC22A5 activity modulation in sensitizing glioma cells to the suppression of fatty acid oxidation by CPT1...

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Barbara Elżbieta Juraszek

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  7. Nanoencapsulated Photosensitizing Drugs for Photodynamic Therapy of Resistant Cancers and Microbes

    Call: SONATA BIS 6 , Panel: NZ7

    Principal investigator: dr Janusz Marcin Dąbrowski

    Uniwersytet Jagielloński, Wydział Chemii

  8. Rescue from bone loss, diminished mineral density and strength in mice after treatment with steroid and nonsteroid anti-...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: prof. Maciej Zbigniew Głowacki

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski

  9. Old drugs - new perspectives: modulation of antibiotics activity by caffeine and pentoxifylline

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Anna Woziwodzka

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  10. Modified borondipyrromethane derivatives (BODIPY) with selective photodynamic activity against cancer and bacterial cell...

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr hab. Jarosław Piskorz

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  11. An elaboration of analytical method for detection of non-steroidal anti-inflammatory drugs in equestrian nutritional and...

    Call: PRELUDIUM 11 , Panel: ST4

    Principal investigator: Emilia Waraksa

    Instytut Sportu - Państwowy Instytut Badawczy

  12. The importance of interaction between NMDA and AMPA receptors and scaffolding proteins in the excitatory synaptic in the...

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: dr hab. Magdalena Jolanta Sowa-Kućma

    Uniwersytet Rzeszowski, Kolegium Nauk Medycznych

  13. The study of the contribution of telomerase regulation to cancer cells resistance to DNA-damaging drugs

    Call: OPUS 11 , Panel: NZ7

    Principal investigator: dr hab. Błażej Rubiś

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  14. Anticancer activity of novel tubulin polymerization inhibitors obtained by the chemical modification of colchicine

    Call: OPUS 11 , Panel: ST5

    Principal investigator: dr hab. Adam Włodzimierz Huczyński

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  15. Pro-nucleotides based on mRNA cap structure - synthesis, biological and biophysical evaluation

    Call: SONATA 11 , Panel: ST5

    Principal investigator: dr Karolina Ewa Piecyk

    Uniwersytet Warszawski, Wydział Chemii

  16. Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa...

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Joanna Gabriela Mika

    Instytut Farmakologii PAN

  17. Assessment of impact heavy metals for mobility and sorption of anticancer drugs residues and their metabolites in enviro...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Katarzyna Mioduszewska

    Uniwersytet Gdański, Wydział Chemii

  18. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Karolina Sylwia Podkowa

    Instytut Farmakologii PAN

  19. The influence of a new hybryd compound derived from 2-(2,5-dioxopyrrolidin-1-yl) propanamide on hippocampal neuroprotect...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Marta Andres-Mach

    Instytut Medycyny Wsi im. Witolda Chodźki

  20. Tick-borne encephalitis virus - search for mechanisms useful in treatment and prophylaxis.

    Call: SONATA 10 , Panel: NZ6

    Principal investigator: dr hab. Ewelina Król

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  21. The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  22. Modified aza-BODIPYs as potential photosensitizers with antibacterial and antifungla activity

    Call: SONATA 10 , Panel: NZ7

    Principal investigator: dr Michał Jakub Kryjewski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  23. The role of inflammation, oxidative and nitrosative stress, tryptophan catabolites pathway and DNA base excision repair ...

    Call: OPUS 10 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  24. Analysis of genetic factors associated with response to glucocorticoid in patient with inflammatory bowel disease

    Call: PRELUDIUM 9 , Panel: NZ5

    Principal investigator: Marcin Gabryel

    Instytut Genetyki Człowieka PAN

  25. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Irena Maria Nalepa

    Instytut Farmakologii PAN

  26. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  27. The application of a modern chromatographic platform with biodetection: HPLC-DAD/MAO A/ESI-TOF-MS in the antidepressant ...

    Call: SONATA 9 , Panel: NZ7

    Principal investigator: dr hab. Wirginia Anna Kukuła-Koch

    Uniwersytet Medyczny w Lublinie, Wydział Farmaceutyczny

  28. Interactions between commonly used antiarrhythmic and antiepileptic drugs in the model of generalized tonic-clonic convu...

    Call: OPUS 9 , Panel: NZ4

    Principal investigator: prof. Kinga Katarzyna Borowicz - Reutt

    Uniwersytet Medyczny w Lublinie, Wydział Lekarski

  29. Optimization of systemic infections treatment in patients receiving parenteral nutrition - stability and compatibility s...

    Call: SONATA 9 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Dettlaff

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Farmaceutyczny

  30. The role of DNA methylation in enhancing the sensitivity of colorectal cancer cells to topoisomerase inhibitors.

    Call: PRELUDIUM 9 , Panel: NZ3

    Principal investigator: Alicja Patrycja Pawlak

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  31. Comparative mRNA expression, protein abundance and regulatory mechanisms of drug metabolising eznymes and transporters i...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Marek Droździk

    Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Lekarski z Oddziałem Nauczania w Języku Angielskim

  32. Effect of physical processes and excipients on properties of poorly water-soluble active pharmaceutical ingredients

    Call: SYMFONIA 3 , Panel: NZ7

    Principal investigator: prof. Marian Wilhelm Paluch

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Ścisłych i Technicznych

  33. Abeta 4-x peptides as copper binding molecules resistant to chelating drugs, promoting the formation of amyloid oligomer...

    Call: OPUS 8 , Panel: ST5

    Principal investigator: prof. Wojciech Bal

    Instytut Biochemii i Biofizyki PAN

  34. Functionalized carbohydrates pharmacophores as a putative antituberculosis drugs - the mechanism of action.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: prof. Jarosław Dziadek

    Instytut Biologii Medycznej PAN

  35. New anti-leukemia drugs - advanced preclinical studies.

    Call: OPUS 8 , Panel: NZ7

    Principal investigator: prof. Urszula Wojda

    Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

  36. Late Neolithic/Early Bronze Age developments in the south-west Baltic Area (2500-1500 BC): Why did the Bruszczewo-Łęki M...

    Call: BEETHOVEN 1 , Panel: HS3

    Principal investigator: prof. Janusz Czebreszuk

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Archeologii

  37. Legal tools used to delay the entry of generic drugs into market

    Call: OPUS 8 , Panel: HS5

    Principal investigator: dr hab. Marek Krzysztof Kolasiński

    Uniwersytet Mikołaja Kopernika, Wydział Prawa i Administracji

  38. Molecular mechanism of epigenetic drugs action to prevent multi-organ injury in a mouse model of sepsis

    Call: HARMONIA 6 , Panel: NZ5

    Principal investigator: dr Michał Marek Mikula

    Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

  39. Characteristics of neuropilin-1 (NRP1) as a target of antiangiogenic activity of immunomodulatory drugs in multiple myel...

    Call: OPUS 7 , Panel: NZ6

    Principal investigator: prof. Krzysztof Giannopoulos

    Uniwersytet Medyczny w Lublinie, II Wydział Lekarski z Oddziałem Anglojęzycznym

  40. The search for innovative solutions in terms of the determination of antibacterial agents in agricultural soils

    Call: PRELUDIUM 7 , Panel: ST4

    Principal investigator: Paulina Łukaszewicz

    Uniwersytet Gdański, Wydział Chemii

  41. Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha...

    Call: PRELUDIUM 7 , Panel: NZ6

    Principal investigator: Katarzyna Curzytek

    Instytut Farmakologii PAN

  42. Study on improving the selectivity and activity of selected drugs and natural compounds with anticancer properties due t...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Włodzimierz Wiktor Lewandowski

    POLITECHNIKA BIAŁOSTOCKA, Wydział Budownictwa i Inżynierii Środowiska

  43. Applications of High Resolution Magic Angle Spinning Spectroscopy in research of selected anticancer drug embedded in me...

    Call: PRELUDIUM 7 , Panel: ST5

    Principal investigator: Ewa Agnieszka Skorupska

    Centrum Badań Molekularnych i Makromolekularnych PAN

  44. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  45. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap...

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

    Instytut Farmakologii PAN

  46. Design and synthesis of the porous materials based on biopolymers and their composites with magnetite as potential sorbe...

    Call: OPUS 7 , Panel: ST8

    Principal investigator: dr Anna Daria Kaczmarek-Kędziera

    Uniwersytet Mikołaja Kopernika, Wydział Chemii

  47. New potential immunosuppressing drug based on the structures of adenosine and mycophenolic acid - synthesis and biologic...

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Krystyna Jolanta Dzierzbicka

    Politechnika Gdańska, Wydział Chemiczny

  48. Synthesis of pyridopyrimidine derivatives, dual affinity ligands for 5-HT1AR and SERT.

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Franciszek Herold

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  49. Endogenous enkephalinase inhibitors and their novel synthetic analogs as potential new therapeutics for the treatment of...

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: dr hab. Jakub Jerzy Fichna

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  50. Novel peptide inhibitors of dipeptidyl peptidase IV (DPP IV) as novel approach for diabetes type 2 and inflammatory bowe...

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Maciej Stanisław Sałaga

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski