Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Drug transporters and their regulation in liver pathology

2015/18/M/NZ7/00410

Keywords:

drug transporters liver pathology

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Pomorski Uniwersytet Medyczny w Szczecinie, Wydział Medycyny i Stomatologii

woj. zachodniopomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marek Droździk 

Number of co-investigators in the project: 5

Call: HARMONIA 7 - announced on 2015-06-15

Amount awarded: 1 103 964 PLN

Project start date (Y-m-d): 2016-04-11

Project end date (Y-m-d): 2021-04-10

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. The reference liver – ABC and SLC drug transporters in healthy donor and metastatic livers
    Authors:
    Kurzawski M., Szeląg-Pieniek S., Łapczuk-Romańska J., Wrzesiński M., Sieńko J., Oswald S., Droździk M
    Academic press:
    Pharmacol Rep. (rok: 2019, tom: 71, strony: 738-745), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1016/j.pharep.2019.04.001 - link to the publication
  2. Extrahepatic drug transporters in liver failure: focus on kidney and gastrointestinal tract
    Authors:
    Droździk M., Oswald S., Drozdzik A
    Academic press:
    Int. J. Mol. Sci. (rok: 2020, tom: 21, strony: 5737), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21165737 - link to the publication
  3. Identifying differentially expressed microRNAs, target genes and key pathways deregulated in patients with liver diseases
    Authors:
    Gholizadeh M., Szelag-Pieniek S., Post M., Kurzawski M., Prieto J., Argemi J., Drozdzik M., Kaderali L
    Academic press:
    Int. J. Mol. Sci. (rok: 2020, tom: 21, strony: 7368), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21197368 - link to the publication
  4. Protein abundance of hepatic drug transporters in patients with different forms of liver damage
    Authors:
    Marek Drozdzik, Sylwia Szelag-Pieniek, Mariola Post, Samir Zeair, Maciej Wrzesinski, Mateusz Kurzawski, Jesus Prieto, Stefan Oswald
    Academic press:
    Clinical Pharmacology and Therapeutics (rok: 2020, tom: 107, strony: 1138-1148), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/cpt.1717 - link to the publication