An elaboration of analytical method for detection of non-steroidal anti-inflammatory drugs in equestrian nutritional and dietary supplements and investigation of these preparations for the presence of doping agents

2016/21/N/ST4/02342

Keywords

Descriptors

  • ST4_6: Chemia analityczna
  • ST4_3: Metody spektroskopowe i spektrometryczne

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Instytut Sportu - Państwowy Instytut Badawczy

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Emilia Waraksa

Number of co-investigators in the project: 3

Call

PRELUDIUM 11 – announced on 2016-03-15

Amount awarded
99 040 PLN
Project start date
2017-04-03
Project end date
2019-04-02
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Koncentrator blokowy. Cost: 27 995 PLN

Information in the final report

Publication in academic press/journals (7)

  1. Determination of bromhexine and its metabolites in equine serum samples by liquid chromatography – tandem mass spectrometry: Applicability to the elimination study after single oral dose

    Authors:
    E. Waraksa, K. Owczarek, P. Kubica, E. Kłodzińska, M. Ozimek, R. Wrzesień, B. Bobrowska-Korczak, J. Namieśnik
    Academic press:
    Journal of Chromatography B (year: 2020, volume: 1151, pages: 122197), Publisher: Springer
    Status:
    Published
    DOI:
    10.1016/j.jchromb.2020.122197 – link to the publication
  2. Nonsteroidal anti-inflammatory drug metabolism studies in horses in view of doping control: Analytical strategies and challenges

    Authors:
    E. Waraksa, W. Filipiak, E. Kłodzińska, M. Ozimek, M. Konop, J. Namieśnik
    Academic press:
    Analytical Methods (year: 2019, volume: 11, pages: 3767), Publisher: Royal Society of Ciemistry
    Status:
    Published
    DOI:
    10.1039/c9ay00692c – link to the publication
  3. A rapid and eco-friendly method for determination of the main components of gamma-oryzanol in equestrian dietary and nutritional supplements by liquid chromatography—tandem mass spectrometry

    Authors:
    E. Waraksa, K. Kowalski, E. Kłodzińska, R. Rola, J. Ciekot, W. Filipiak, T. Bieńkowski, J. Namieśnik
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (year: 2019, volume: 172, pages: 339-348), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2019.04.029 – link to the publication
  4. Determination of free tyrosine in equestrian supplements by LC–MS/MS and comparison of its quantity with total free amino acids content in view of doping control

    Authors:
    E. Waraksa, K. Kowalski, R. Rola, E. Kłodzińska, T. Bieńkowski, J. Namieśnik
    Academic press:
    Microchemical Journal (year: 2019, volume: 146, pages: 56-65), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.microc.2018.12.033 – link to the publication
  5. Comparison of GC–MS and MEKC methods for caffeine determination in preworkout supplements

    Authors:
    E. Waraksa, A. Pokrywka, M. Konop, J. Namieśnik, E. Kłodzińska
    Academic press:
    Electrophoresis (year: 2019, volume: 40, pages: 1540), Publisher: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/elps.201800512 – link to the publication
  6. A rapid and sensitive method for quantitative analysis of ibuprofen and its metabolites in equine urine samples by gas chromatography-tandem mass spectrometry

    Authors:
    E. Waraksa, M.K. Woźniak, E. Kłodzińska, R. Wrzesień, B. Bobrowska-Korczak, J. Namieśnik
    Academic press:
    Journal of Separation Science (year: 2018, volume: 41, pages: 3881), Publisher: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/jssc.201800614 – link to the publication
  7. Quantification of unconjugated and total ibuprofen and its metabolites in equine urine samples by gas chromatography–tandem mass spectrometry: Application to the excretion study

    Authors:
    E. Waraksa, M.K. Woźniak, L. Banaszkiewicz, E. Kłodzińska, M. Ozimek, R. Wrzesień, B. Bobrowska-Korczak, J. Namieśnik
    Academic press:
    Microchemical Journal (year: 2019, volume: 150, pages: 104129), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.microc.2019.104129 – link to the publication

Articles in post-conference publications (2)

  1. Oznaczanie głównych składników gamma-oryzanolu i tyrozyny w odżywkach i suplementach diety z zastosowaniem chromatografii cieczowej sprzężonej z tandemową spektrometrią mas

    Authors:
    E. Waraksa, E. Kłodzińska, J. Namieśnik
    Conference:
    Międzynarodowy Zjazd Naukowego Polskiego Towarzystwa Medycyny Sportowej. Medycyna dla sportu, sport dla medycyny (year: 2018, pages: 40-41), Publisher: Medycyna Sportowa Polish Journal of Sports Medicine
    Date:
    conference 27-29.09.2018
    Status:
    Published
  2. Identyfikacja głównych składników gamma-oryzanolu w suplementach przeznaczonych dla koni

    Authors:
    E. Waraksa, E. Kłodzińska, J. Namieśnik
    Conference:
    III Konferencja Młodych Chemików Sądowych (year: 2018, pages: 28-29), Publisher: Wydział Chemii Uniwersytet Jagielloński w Krakowie
    Date:
    conference 15-16.04.2018 r.
    Status:
    Published

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