Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Design of enzyme systems for the study of chiral drugs with the use of superparamagnetic nanoparticles as carriers for biocatalysts

2013/09/N/NZ7/03557

Keywords:

chiral drugs enzymes superparamagnetic nanoparticles biocatalysis

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Tomasz Siódmiak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 139 996 PLN

Project start date (Y-m-d): 2014-02-21

Project end date (Y-m-d): 2017-02-20

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Termostat do kolumn do HPLC (13 000 PLN)
  2. Inkubator (28 000 PLN)
  3. Pompa dwutłokowa do HPLC.

Information in the final report

  • Publication in academic press/journals (2)
  1. High Enantioselective Novozym 435-Catalyzed Esterification of (R,S)-Flurbiprofen Monitored with a Chiral Stationary Phase
    Authors:
    Tomasz Siódmiak, Debby Mangelings, Yvan Vander Heyden, Marta Ziegler-Borowska, Michał Piotr Marszałł
    Academic press:
    Applied Biochemistry and Biotechnology (rok: 2015, tom: 175, strony: 2769-2785), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12010-014-1455-4 - link to the publication
  2. Synthesis of new chitosan coated magnetic nanoparticles with surface modified with long-distanced amino groups as a support for bioligands binding
    Authors:
    Marta Ziegler-Borowska, Dorota Chełminiak, Tomasz Siódmiak, Adam Sikora, Michał Piotr Marszałł, Halina Kaczmarek
    Academic press:
    Materials Letters (rok: 2014, tom: 132, strony: 63–65), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.matlet.2014.06.020 - link to the publication

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