Search results

1. Age- and tissue-related endogenous breaks in nuclear and mitochondrial DNA, and their link to cytoplasmic DNA - direct i…

Principal investigator: prof. Jerzy Dobrucki

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 26, Panel: NZ3

2. Differential activity of ribonucleotide repair on leading and lagging DNA strand and its consequences for the mechanism …

Principal investigator: Krystian Łazowski

Instytut Biochemii i Biofizyki PAN

Call: PRELUDIUM 18, Panel: NZ1

3. Uracil in DNA and aberrant DNA methylation/hydroxymethylation as a new biomarkers of multiple myeloma development? A sea…

Principal investigator: prof. Ryszard Oliński

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

Call: OPUS 20, Panel: NZ5

4. Double stranded probes, in which both oligonucleotide components hybridize according to the Hoogsteen's interactions, an…

Principal investigator: dr hab. Piotr Jerzy Guga

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 10, Panel: ST5

5. MOLECULES BINDING DNA - SYNTHESIS AND PROPERTIES OF DNA INTERCALATORS CONTAINING BORON CLUSTERS.

Principal investigator: dr hab. Agnieszka Bogusława Olejniczak

Instytut Biologii Medycznej PAN

Call: SONATA BIS 4, Panel: ST5

6. P-Stereodefined phosphorothioate analogs of DNA containing within nucleobases modifications preventing Watson-Crick base…

Principal investigator: dr Anna Maciaszek

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 6, Panel: ST5

7. The role of DNA translocase Irc5 in DNA damage response in Saccharomyces cerevisiae

Principal investigator: dr Ireneusz Bernard Litwin

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: SONATA 6, Panel: NZ2

8. Stereodefined phosphorothioate analogs of DNA with incorporated LNA-type nucleosides - synthesis and properties of compl…

Principal investigator: dr hab. Piotr Jerzy Guga

Centrum Badań Molekularnych i Makromolekularnych PAN

Call: OPUS 2, Panel: ST5

9. Biological functions of Uls1, a member of ATP-dependent DNA translocase from SWI2/SNF2 family, in replication, DNA damag…

Principal investigator: prof. Robert Wysocki

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: OPUS 2, Panel: NZ2

10. Two-photon excited fluorescence microscopy of model DNA systems - dyes and metal nanoparticles as biolabels in DNA imagi…

Principal investigator: dr Joanna Olesiak-Bańska

Politechnika Wrocławska, Wydział Chemiczny

Call: PRELUDIUM 1, Panel: ST5

11. The functional role of non-catalytic Pol32p subunit of DNA polymerase delta at the replication fork.

Principal investigator: dr Katarzyna Anna Grabowski

Instytut Biochemii i Biofizyki PAN

Call: OPUS 2, Panel: NZ1

12. Global and local chromatin reorganisation in cellular response to DNA double-strand breaks, investigated with super-reso…

Principal investigator: prof. Jerzy Dobrucki

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 14, Panel: NZ3

13. Novel factors involved in cell cycle control after DNA damage.

Principal investigator: dr Michał Zbigniew Malewicz

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Call: OPUS 21, Panel: NZ1

14. Functions of post-translational modifications of key proteins involved in DNA repair.

Principal investigator: dr Michał Zbigniew Malewicz

Sieć Badawcza ŁUKASIEWICZ - PORT Polski Ośrodek Rozwoju Technologii

Call: OPUS 20, Panel: NZ3

15. Nanospectroscopic investigation into DNA local structural transitions upon oxidative damage and its repair

Principal investigator: dr hab. Ewelina Lipiec

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: PRELUDIUM BIS 2, Panel: NZ1

16. Local structural transitions in DNA molecule upon damage and repair

Principal investigator: prof. Marek Leszek Szymoński

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Call: OPUS 16, Panel: ST4

17. Mechanisms of activation of Short-Patch and Long-Patch DNA repair pathways in different phases of the cell cycle

Principal investigator: Oskar Mateusz Szelest

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 14, Panel: NZ1

18. Contribution of DNA polymerase delta in the leading strand replication in Saccharomyces cerevisiae cells

Principal investigator: prof. Iwona Jadwiga Fijałkowska

Instytut Biochemii i Biofizyki PAN

Call: OPUS 9, Panel: NZ1

19. Quantitative analysis of spontaneous single-strand DNA breaks and ensuing replication stress in human cells.

Principal investigator: Magdalena Maria Kordon

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 5, Panel: NZ3

20. DNA double-stranded break repair proteins as a target for personalized cancer therapy based on synthetic lethality

Principal investigator: dr hab. Tomasz Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 4, Panel: NZ7

21. Role of mitochondrial DNA damage and repair in the resistance of BCR/ABL-expressing cells to imatinib

Principal investigator: prof. Janusz Błasiak

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 2, Panel: NZ2

22. Mechanistic and structural studies of adenoviral DNA replication

Principal investigator: prof. Marcin Piotr Nowotny

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Call: OPUS 28, Panel: NZ1

23. The association between the repair of oxidative DNA lesions and Th17/Treg cell homeostasis in Patients with Rheumatoid A…

Principal investigator: Gabriela Filipowicz

Instytut Reumatologii im. prof. dr hab. med. Eleonory Reicher

Call: PRELUDIUM 23, Panel: NZ5

24. New insight into the structure and function of the DNA segregation systems of alphaproteobacterial repABC plasmids and s…

Principal investigator: Elvira Krakowska

Uniwersytet Warszawski, Wydział Biologii

Call: PRELUDIUM 22, Panel: NZ2

25. Atlantification of the European Arctic across geological times: new insights from sedimentary ancient DNA.

Principal investigator: dr Joanna Pawłowska

Instytut Oceanologii PAN

Call: OPUS 24, Panel: ST10

26. Genomic landscape of arsenic-induced DNA damage and repair

Principal investigator: dr Ireneusz Bernard Litwin

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: OPUS 24, Panel: NZ2

27. The effects of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors on changes in selected epigenetic mechan…

Principal investigator: Agnieszka Magdalena Woźniak

Uniwersytet Medyczny w Łodzi, Wydział Lekarski

Call: PRELUDIUM 21, Panel: NZ7

28. Radiosensitization by the combined use of modified nucleosides and inhibitors of DNA repair to improve the efficacy of r…

Principal investigator: dr Magdalena Danuta Zdrowowicz-Żamojć

Uniwersytet Gdański, Wydział Chemii

Call: SONATA 17, Panel: ST4

29. Photodamage and self-healing of primordial forms of DNA and RNA.

Principal investigator: dr Rafał Kazimierz Szabla

Politechnika Wrocławska

Call: OPUS 19, Panel: ST4

30. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

Principal investigator: prof. Tomasz Adam Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 19, Panel: NZ7

31. Deciphering the role of putative protein factors involved in the mycobacterial DNA strand break repairs

Principal investigator: dr Przemysław Adam Płociński

Instytut Biologii Medycznej PAN

Call: OPUS 17, Panel: NZ1

32. Identification and functional characterization of long non-coding RNAs involved in the ATM-dependent response to DNA dam…

Principal investigator: dr hab. Agnieszka Dzikiewicz-Krawczyk

Instytut Genetyki Człowieka PAN

Call: OPUS 14, Panel: NZ1

33. Adaptation of electrophoretic methods for the determination of the impact of food components on global DNA methylation.

Principal investigator: Monika Baranowska

Politechnika Gdańska, Wydział Chemiczny

Call: PRELUDIUM 14, Panel: NZ9

34. The CMGE helicase-polimerase complex a factor integrating the regulation of cell cyle progression and DNA replication

Principal investigator: dr Michał Jerzy Dmowski

Instytut Biochemii i Biofizyki PAN

Call: HARMONIA 9, Panel: NZ3

35. Functional, genetic and epigenetic aspects of DNA repair in Rheumatoid arthritis

Principal investigator: dr hab. Tomasz Popławski

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 13, Panel: NZ6

36. Influence of (5'R) and (5'S) 5',8-cyclo-2'-deoxypurines on clustered DNA lesions repair

Principal investigator: dr hab. Bolesław Tomasz Karwowski

Uniwersytet Medyczny w Łodzi, Wydział Farmaceutyczny

Call: OPUS 12, Panel: NZ7

37. Precision medicine-guided synthetic lethality targeting DNA repair to eradicate solid tumors

Principal investigator: dr hab. Tomasz Śliwiński

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: HARMONIA 8, Panel: NZ7

38. RNA-directed DNA methylation under heat stress in Arabidopsis thaliana

Principal investigator: dr Urszula Korotko

UNIWERSYTET ŚLĄSKI, Wydział Biologii i Ochrony Środowiska

Call: PRELUDIUM 11, Panel: NZ2

39. Heterochromatin protein 1 as a structure-stabilizing factor in repair of DNA double-strand breaks.

Principal investigator: dr Krzysztof Łukasz Berniak

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: PRELUDIUM 10, Panel: NZ1

40. Products of DNA demethylation and deamination pathways as new biomarkers of development and predictors of the outcome in…

Principal investigator: dr hab. Daniel Stefan Gackowski

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

Call: OPUS 10, Panel: NZ5

41. Embryotoxicity and teratogenicity as a result of response to DNA damage in iPS cells: the effect of methylmercury chlori…

Principal investigator: Justyna Augustyniak

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

Call: PRELUDIUM 9, Panel: NZ7

42. Mitochondrial DNA damage and repair in depression

Principal investigator: Piotr Lech Czarny

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: PRELUDIUM 7, Panel: NZ7

43. Super-resolution optical imaging of higher order chromatin structures in nuclei of human cells, during DNA replication a…

Principal investigator: prof. Jerzy Dobrucki

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Call: OPUS 6, Panel: NZ3

44. Sensitization of cancer cells to chemotherapy by novel DNA repair inhibitors

Principal investigator: dr hab. Tomasz Popławski

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

Call: OPUS 6, Panel: NZ7

45. A search for a link between epigenetical changes - active DNA demethylation and oxidative stress based on cell culture s…

Principal investigator: prof. Ryszard Oliński

Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy; Wydział Farmaceutyczny

Call: OPUS 4, Panel: NZ1

46. New chemical and biological properties of topoizomeraze I inhibitors alkylating DNA oligomers

Principal investigator: prof. Lech Jan Kozerski

Instytut Chemii Organicznej Polska Akademia Nauk

Call: OPUS 4, Panel: ST4

47. Association between genetic polimorphisms in selected antioxidant enzymes genes and DNA repair genes and oxidative damag…

Principal investigator: Elżbieta Marta Olewińska

Instytut Medycyny Pracy i Zdrowia Środowiskowego

Call: PRELUDIUM 2, Panel: NZ7

48. Novel DNA Minor Groove Helix Alkylating Agents - Design, Synthesis and Antitumor Activity Screening

Principal investigator: dr Adam Józef Mieczkowski

Instytut Biochemii i Biofizyki PAN

Call: OPUS 1, Panel: NZ4

49. Role of DNA translocase in replication stress response in the yeast Saccharomyces cerevisiae

Principal investigator: Magdalena Cal-Bąkowska

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

Call: PRELUDIUM 1, Panel: NZ1

50. Is ADP-ribosylation involved in the response to DNA double-strand breaks? An investigation employing the CRISPR-Cas9 sys…

Principal investigator: Weronika Justyna Pawluś

Uniwersytet Jagielloński

Call: PRELUDIUM 24, Panel: NZ3

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