Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Mitochondrial DNA damage and repair in depression

2014/13/N/NZ7/00232

Keywords:

depression oxidative DNA damage mitochondrial DNA repair and degradation of mtDNA

Descriptors:

  • NZ7_12: Prevention of human diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Piotr Czarny 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 98 904 PLN

Project start date (Y-m-d): 2015-03-05

Project end date (Y-m-d): 2017-03-04

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (1)
  1. Mitochondrial DNA copy number, damage, repair and degradation in depressive disorder
    Authors:
    Czarny P, Wigner P, Strycharz J, Swiderska E, Synowiec E, Szatkowska M, Sliwinska A, Talarowska M, Szemraj J, Su KP, Maes M, Sliwinski T, Galecki P
    Academic press:
    The World Journal of Biological Psychiatry (rok: 2019, tom: bd, strony: 45302), Wydawca: TAYLOR & FRANCIS LTD
    Status:
    Published
    DOI:
    10.1080/15622975.2019.1588993 - link to the publication
  2. Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder
    Authors:
    Czarny P, Kwiatkowski D, Toma M, Galecki P, Orzechowska A, Bobinska K, Bielecka-Kowalska A, Szemraj J, Berk M, Anderson G, Sliwinski T
    Academic press:
    Medical Science Monitor (rok: 2016, tom: 22, strony: 4455-4474), Wydawca: Thomson Reuters
    Status:
    Published
    DOI:
    10.12659/MSM.898091 - link to the publication
  3. The interplay between inflammation, oxidative stress, DNA damage, DNA repair and mitochondrial dysfunction in depression
    Authors:
    Czarny P, Wigner P, Gałecki P, Śliwiński T
    Academic press:
    Progress in Neuro-Psychopharmacology and Biological Psychiatry (rok: 2018, tom: 80, strony: 309-321), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pnpbp.2017.06.036 - link to the publication
  4. Impact of Single Nucleotide Polymorphisms of Base Excision Repair Genes on DNA Damage and Efficiency of DNA Repair in Recurrent Depression Disorder
    Authors:
    Czarny P, Kwiatkowski D, Toma M, Kubiak J, Sliwinska A, Talarowska M, Szemraj J, Maes M, Galecki P, Sliwinski T
    Academic press:
    Molecular Neurobiology (rok: 2017, tom: 54, strony: 4150-4159), Wydawca: Springer
    Status:
    Accepted for publication
    DOI:
    10.1007/s12035-016-9971-6 - link to the publication
  5. Stres oksydacyjny oraz uszkodzenia i naprawa DNA w zaburzeniach depresyjnych
    Authors:
    Czarny P, Gałecki P, Śliwiński T
    Academic press:
    Farmakoterapia w Psychiatrii i Neurologii (rok: 2015, tom: 31, strony: 243-249), Wydawca: Instytut Psychiatrii i Neurologii
    Status:
    Published
    DOI:
    10.17393/fpn.2016.01.006 - link to the publication
  1. Association between single-nucleotide polymorphisms of genes responsible for repair, replication and degradation of mitochondrial DNA, and depression disorder
    Authors:
    Czarny P, Wigner P, Szmeraj J, Sliwinski T
    Conference:
    6th Central European Congress of Life Sciences Eurobiotech 2017 (rok: 2017, ), Wydawca: Targi w Krakowie Ltd.
    Data:
    konferencja 11-14 września 2017
    Status:
    Published